Cell Biology

Organization of the yeast Seipin complex reveals differential recruitment of regulatory proteins

1. Yoel A. Klug
2. Pedro Carvalho

Reviewed by Review Commons

Fertilization triggers cytosolic functions and P-body recruitment of the RNA-binding protein Mei2 to drive fission yeast zygotic development

1. Ayokunle Araoyinbo
2. Clàudia Salat-Canela
3. Aleksandar Vještica

Reviewed by Review Commons

Optogenetic control of mechanotransduction based on light-induced homodimerization of talin

1. Ryosuke Nishimura
2. Samuel F. H. Barnett
3. Kashish Jain
4. Zengxin Huang
5. Benjamin T. Goult
6. Pakorn Kanchanawong

Reviewed by preLights

Live-cell imaging reveals nutrient-dependent dynamics of ER-mitochondria contact formation via PDZD8

1. Saeko Aoyama-Ishiwatari
2. Koki Nakamura
3. Takahiro Nagao
4. Yusuke Hirabayashi

Reviewed by Review Commons

G1 and G2 ApolipoproteinL1 modulate macrophage inflammation and lipid accumulation through the polyamine pathway

1. Esther Liu
2. Matthew Wright
3. Andrew O Kearney
4. Tiffany Caza
5. Johnson Y Yang
6. Valerie Garcia
7. Amal O Dadi
8. Shuta Ishibe
9. Navdeep S Chandel
10. Hanrui Zhang
11. Edward B Thorp
12. Jennie Lin

• Curated by eLife

  eLife Assessment

  The authors study how apolipoprotein L1 variants impact inflammation and lipid accumulation in macrophages. The findings will be useful for researchers investigating macrophage metabolism and inflammation. The discovery that the polyamine spermidine in part mediates such effects is interesting, but the supporting evidence for a physiologically relevant role is currently incomplete due to the lack of relevant in vivo studies.

Reviewed by eLife