Cell Biology

IFT20 regulates lymphatic endothelial cell-cell junctions via endocytic trafficking of VE-cadherin

1. Delayna Paulson
2. Ahana Majumder
3. Zachary Lehmann
4. Luke Knutson
5. Jacob Paulson
6. Shannon Lasey
7. Darci M. Fink

Reviewed by Review Commons

Treacle’s ability to form liquid-like phase condensates is essential for nucleolar fibrillar center assembly, efficient rRNA transcription and processing, and rRNA gene repair

1. Artem K Velichko
2. Nadezhda V Petrova
3. Dmitry A Deriglazov
4. Anastasia P Kovina
5. Artem V Luzhin
6. Eugene P Kazakov
7. Igor I Kireev
8. Sergey Razin
9. Omar L Kantidze

• Curated by eLife

  eLife Assessment

  This important study reveals that the nucleolar protein Treacle undergoes liquid-liquid phase separation in vitro and in vivo. It provides convincing evidence that the ability of Treacle to form phase-separated condensates is necessary for the proper formation of the fibrillar center of the nucleolus, rRNA transcription, and rDNA repair. These findings will be of interest to the communities studying biomolecular condensates, nucleolar organization, and ribosome biogenesis.

Reviewed by eLife

Teach your microscope how to print: Low-cost and rapid-iteration microfabrication for biology

1. Lucien Hinderling
2. Remo Hadorn
3. Moritz Kwasny
4. Joël Frei
5. Benjamin Grädel
6. Sacha Psalmon
7. Yannick Blum
8. Rémi Berthoz
9. Alex Landolt
10. Benjamin D. Towbin
11. Daniel Riveline
12. Olivier Pertz

Reviewed by Arcadia Science

Membrane microdomains are crucial for Mycobacterium marinum EsxA-dependent membrane damage, escape to the cytosol and infection

1. Cristina Bosmani
2. Angélique Perret
3. Florence Leuba
4. Aurélie Guého
5. Nabil Hanna
6. Thierry Soldati

Reviewed by Review Commons

Intestinal fibroblast heterogeneity: unifying RNA-seq studies and introducing consensus-driven nomenclature

1. Neda Glisovic
2. Aleksandra Chikina
3. Noémie Robil
4. Sonia Lameiras
5. Danijela Matic Vignjevic

Reviewed by Review Commons

Chromatin organization controls nuclear stiffness

1. Hector Romero
2. Anahid Amiri
3. Maruthi K. Pabba
4. Hui Zhang
5. Veronika Berg
6. Maria Arroyo
7. Paulina Prorok
8. Nina Trautwein
9. Bodo Laube
10. Christian Dietz
11. Robert W. Stark
12. M. Cristina Cardoso

Reviewed by Life Science Editors Foundation

SUMOylation regulates protein cargo in Astrocyte-derived small extracellular vesicles

1. Anllely Fernández
2. Maxs Méndez
3. Octavia Santis
4. Katherine Corvalan
5. Maria-Teresa Gomez
6. Peter Landgraf
7. Thilo Kahne
8. Alejandro Rojas-Fernandez
9. Ursula Wyneken

Reviewed by PREreview

Interferon-Induced PARP14-Mediated ADP-Ribosylation in p62 Bodies Requires an Active Ubiquitin-Proteasome System

1. Rameez Raja
2. Banhi Biswas
3. Rachy Abraham
4. Hongrui Liu
5. Che-Yuan Chang
6. Hien Vu
7. Anthony K. L. Leung

Reviewed by PREreview, Review Commons

Chromokinesin Klp-19 regulates microtubule overlap and dynamics during anaphase in C. elegans

1. Vitaly Zimyanin
2. Magdalena Magaj
3. Nadia Ingabire Manzi
4. Che-Hang Yu
5. Theresa Gibney
6. Yu-Zen Chen
7. Mustafa Basaran
8. Xavier Horton
9. Karsten Siller
10. Ariel Pani
11. Daniel Needleman
12. Daniel J. Dickinson
13. Stefanie Redemann

Reviewed by Review Commons

IDH1 regulates human erythropoiesis by eliciting chromatin state reprogramming

1. Mengjia Li
2. Hengchao Zhang
3. Xiuyun Wu
4. Mengqi Yu
5. Qianqian Yang
6. Lei Sun
7. Wei Li
8. Zhongxing Jiang
9. Fumin Xue
10. Ting Wang
11. Xiuli An
12. Lixiang Chen

• Curated by eLife

  eLife Assessment

  This study by Li et al. presents important findings on the metabolism-independent role of nuclear IDH1 in chromatin regulation during erythropoiesis. The authors provide convincing evidence that IDH1 deficiency disrupts H3K79 methylation and nuclear architecture, contributing to dyserythropoiesis. Their findings offer invaluable mechanistic insights with potential therapeutic implications for erythroid disorders and hematologic malignancies.

Reviewed by eLife