1. Intestinal fibroblast heterogeneity: unifying RNA-seq studies and introducing consensus-driven nomenclature

    This article has 5 authors:
    1. Neda Glisovic
    2. Aleksandra Chikina
    3. Noémie Robil
    4. Sonia Lameiras
    5. Danijela Matic Vignjevic

    Reviewed by Review Commons

    This article has 3 evaluationsAppears in 1 listLatest version Latest activity
  2. Chromatin organization controls nuclear stiffness

    This article has 12 authors:
    1. Hector Romero
    2. Anahid Amiri
    3. Maruthi K. Pabba
    4. Hui Zhang
    5. Veronika Berg
    6. Maria Arroyo
    7. Paulina Prorok
    8. Nina Trautwein
    9. Bodo Laube
    10. Christian Dietz
    11. Robert W. Stark
    12. M. Cristina Cardoso

    Reviewed by Life Science Editors Foundation

    This article has 1 evaluationAppears in 1 listLatest version Latest activity
  3. SUMOylation regulates protein cargo in Astrocyte-derived small extracellular vesicles

    This article has 9 authors:
    1. Anllely Fernández
    2. Maxs Méndez
    3. Octavia Santis
    4. Katherine Corvalan
    5. Maria-Teresa Gomez
    6. Peter Landgraf
    7. Thilo Kahne
    8. Alejandro Rojas-Fernandez
    9. Ursula Wyneken

    Reviewed by PREreview

    This article has 1 evaluationAppears in 1 listLatest version Latest activity
  4. Interferon-Induced PARP14-Mediated ADP-Ribosylation in p62 Bodies Requires an Active Ubiquitin-Proteasome System

    This article has 7 authors:
    1. Rameez Raja
    2. Banhi Biswas
    3. Rachy Abraham
    4. Hongrui Liu
    5. Che-Yuan Chang
    6. Hien Vu
    7. Anthony K. L. Leung

    Reviewed by PREreview, Review Commons

    This article has 5 evaluationsAppears in 2 listsLatest version Latest activity
  5. Chromokinesin Klp-19 regulates microtubule overlap and dynamics during anaphase in C. elegans

    This article has 13 authors:
    1. Vitaly Zimyanin
    2. Magdalena Magaj
    3. Nadia Ingabire Manzi
    4. Che-Hang Yu
    5. Theresa Gibney
    6. Yu-Zen Chen
    7. Mustafa Basaran
    8. Xavier Horton
    9. Karsten Siller
    10. Ariel Pani
    11. Daniel Needleman
    12. Daniel J. Dickinson
    13. Stefanie Redemann

    Reviewed by Review Commons

    This article has 4 evaluationsAppears in 1 listLatest version Latest activity
  6. IDH1 regulates human erythropoiesis by eliciting chromatin state reprogramming

    This article has 12 authors:
    1. Mengjia Li
    2. Hengchao Zhang
    3. Xiuyun Wu
    4. Mengqi Yu
    5. Qianqian Yang
    6. Lei Sun
    7. Wei Li
    8. Zhongxing Jiang
    9. Fumin Xue
    10. Ting Wang
    11. Xiuli An
    12. Lixiang Chen
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      This study by Li et al. presents important findings on the metabolism-independent role of nuclear IDH1 in chromatin regulation during erythropoiesis. The authors provide convincing evidence that IDH1 deficiency disrupts H3K79 methylation and nuclear architecture, contributing to dyserythropoiesis. Their findings offer invaluable mechanistic insights with potential therapeutic implications for erythroid disorders and hematologic malignancies.

    Reviewed by eLife

    This article has 9 evaluationsAppears in 1 listLatest version Latest activity
  7. MARK2 regulates Golgi apparatus reorientation by phosphorylation of CAMSAP2 in directional cell migratio

    This article has 11 authors:
    1. Peipei Xu
    2. Rui Zhang
    3. Zhengrong Zhou
    4. Honglin Xu
    5. Yuejia Li
    6. Mengge Yang
    7. Ruifan Lin
    8. Yingchun Wang
    9. Xiahe Huang
    10. Qi Xie
    11. Wenxiang Meng
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      The authors propose that the kinase MARK2 regulates the Golgi's reorientation towards the cell's leading edge through the regulation of microtubule binding protein CAMSAP2 and its binding to USO1. While the model is interesting and the study is useful, the quantification of an insufficient number of cells and insufficient description of the methods and biological replicates mean the results are inadequate to support the model.

      [Editors' note: this paper was reviewed by Review Commons.]

    Reviewed by eLife

    This article has 4 evaluationsAppears in 1 listLatest version Latest activity
  8. Periosteal skeletal stem cells can migrate into the bone marrow and support hematopoiesis after injury

    This article has 11 authors:
    1. Tony Marchand
    2. Kemi E Akinnola
    3. Shoichiro Takeishi
    4. Maria Maryanovich
    5. Sandra Pinho
    6. Julien Saint-Vanne
    7. Alexander Birbrair
    8. Thierry Lamy
    9. Karin Tarte
    10. Paul Frenette
    11. Kira Gritsman
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      The study presents valuable insights into the role of periosteal stem cells in bone marrow regeneration. The evidence is convincing. The data broadly support their claims and in line with state-of-art methodology. Future study on their model will help to strengthen their discovery further.

    Reviewed by eLife

    This article has 9 evaluationsAppears in 1 listLatest version Latest activity
  9. Identification and comparison of orthologous cell types from primate embryoid bodies shows limits of marker gene transferability

    This article has 10 authors:
    1. Jessica Jocher
    2. Philipp Janssen
    3. Beate Vieth
    4. Fiona C Edenhofer
    5. Tamina Dietl
    6. Anita Térmeg
    7. Paulina Spurk
    8. Johanna Geuder
    9. Wolfgang Enard
    10. Ines Hellmann
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      The authors have generated important resources such as a reference dataset of early primate development by utilizing single-cell transcriptomic technology together with induced pluripotent stem cells (iPSCs) from four primate species: humans, orangutans, cynomolgus macaques, and rhesus macaques. By analyzing marker gene expression and cell types across species during undirected differentiation of iPSCs, the authors provide solid evidence that the transferability of marker genes decreases as the evolutionary distance between species increases. This work demonstrates the extended usage of iPSCs for broader fields, which will benefit several scientific communities including anthropology, comparative biology, and evolutionary biology.

    Reviewed by eLife

    This article has 4 evaluationsAppears in 1 listLatest version Latest activity
  10. Rudhira-mediated microtubule stability controls TGFβ signaling during mouse vascular development

    This article has 4 authors:
    1. Divyesh Joshi
    2. Preeti Jindal
    3. Ronak K Shetty
    4. Maneesha S Inamdar
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      This important work provides another layer of regulatory mechanism for TGF-beta signaling activity. The evidence convincingly supports the involvement of microtubules as a reservoir of Smad2/3, and association of Rudhira with microtubules is critical for this process. The work will be of board interest to developmental biologists in general and molecular biologists in the field of growth factor signaling.

    Reviewed by eLife

    This article has 11 evaluationsAppears in 1 listLatest version Latest activity
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