1. Chronic stress antagonizes formation of Stress Granules

    This article has 6 authors:
    1. Yuichiro Adachi
    2. Allison M. Williams
    3. Masashi Masuda
    4. Yutaka Taketani
    5. Paul J. Anderson
    6. Pavel Ivanov

    Reviewed by preLights

    This article has 1 evaluationAppears in 1 listLatest version Latest activity
  2. Functional redundancy and formin-independent localization of tropomyosin isoforms in Saccharomyces cerevisiae

    This article has 8 authors:
    1. Anubhav Dhar
    2. VT Bagyashree
    3. Sudipta Biswas
    4. Jayanti Kumari
    5. Amruta Sridhara
    6. B Jeevan Subodh
    7. Shashank Shekhar
    8. Saravanan Palani

    Reviewed by Review Commons

    This article has 8 evaluationsAppears in 1 listLatest version Latest activity
  3. Reprograming gene expression in ‘hibernating’ C. elegans involves the IRE-1/XBP-1 pathway

    This article has 5 authors:
    1. Melanie Lianne Engelfriet
    2. Yanwu Guo
    3. Andreas Arnold
    4. Eivind Valen
    5. Rafal Ciosk
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      This useful study reveals that as C. elegans, a poikilothermic ("cold-blooded") animal, adapt to cold (4ºC), they display a drastic reduction in translation (assessed by polysome profiling and SUNSET). The remaining translation (by ribo-seq) correlates with mRNA levels (by RNA-seq), and the changes in gene expression at least partially require IRE-1, an established endoplasmic reticulum stress sensor. The reviewers consider the data assessing global translation and RNA expression upon cold exposure and the data demonstrating the requirement of ire-1 to be solid, but the conclusion that "transcription" is the major regulatory step and "lipid changes" can be a signal for IRE-1 activation in cold adapted worms needs substantially more evidence. Overall, this study demonstrated a good correlation between translation and RNA levels and yielded an inventory of gene changes as C. elegans adapt to cold, and will be of general interest to researchers interested in stress response and cold adaptation.

    Reviewed by eLife

    This article has 8 evaluationsAppears in 1 listLatest version Latest activity
  4. Nucleoporin Nup153 docks the splicing machinery to the nuclear pore for efficient mRNA processing

    This article has 19 authors:
    1. IJ de Castro
    2. L Schuster
    3. C Patiño-Gomez
    4. D Glavas
    5. A Udupa
    6. M Ríos Vázquez
    7. T Symens
    8. G Tulcan
    9. J Heinze
    10. Heras J de las
    11. Robert Reinhardt
    12. Jorge Trojanowski
    13. H Harz
    14. G Stumberger
    15. H Leonhardt
    16. E Schirmer
    17. S Saka
    18. V Laketa
    19. M Lusic

    Reviewed by Review Commons

    This article has 4 evaluationsAppears in 1 listLatest version Latest activity
  5. Optogenetic and chemical genetic tools for rapid repositioning of vimentin intermediate filaments

    This article has 5 authors:
    1. Milena Pasolli
    2. Joyce C. M. Meiring
    3. James P. Conboy
    4. Gijsje H. Koenderink
    5. Anna Akhmanova

    Reviewed by Review Commons

    This article has 4 evaluationsAppears in 1 listLatest version Latest activity
  6. IFT20 regulates lymphatic endothelial cell-cell junctions via endocytic trafficking of VE-cadherin

    This article has 7 authors:
    1. Delayna Paulson
    2. Ahana Majumder
    3. Zachary Lehmann
    4. Luke Knutson
    5. Jacob Paulson
    6. Shannon Lasey
    7. Darci M. Fink

    Reviewed by Review Commons

    This article has 4 evaluationsAppears in 1 listLatest version Latest activity
  7. Treacle’s ability to form liquid-like phase condensates is essential for nucleolar fibrillar center assembly, efficient rRNA transcription and processing, and rRNA gene repair

    This article has 9 authors:
    1. Artem K Velichko
    2. Nadezhda V Petrova
    3. Dmitry A Deriglazov
    4. Anastasia P Kovina
    5. Artem V Luzhin
    6. Eugene P Kazakov
    7. Igor I Kireev
    8. Sergey Razin
    9. Omar L Kantidze
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      This important study reveals that the nucleolar protein Treacle undergoes liquid-liquid phase separation in vitro and in vivo. It provides convincing evidence that the ability of Treacle to form phase-separated condensates is necessary for the proper formation of the fibrillar center of the nucleolus, rRNA transcription, and rDNA repair. These findings will be of interest to the communities studying biomolecular condensates, nucleolar organization, and ribosome biogenesis.

    Reviewed by eLife

    This article has 9 evaluationsAppears in 1 listLatest version Latest activity
  8. Teach your microscope how to print: Low-cost and rapid-iteration microfabrication for biology

    This article has 12 authors:
    1. Lucien Hinderling
    2. Remo Hadorn
    3. Moritz Kwasny
    4. Joël Frei
    5. Benjamin Grädel
    6. Sacha Psalmon
    7. Yannick Blum
    8. Rémi Berthoz
    9. Alex Landolt
    10. Benjamin D. Towbin
    11. Daniel Riveline
    12. Olivier Pertz

    Reviewed by Arcadia Science

    This article has 2 evaluationsAppears in 1 listLatest version Latest activity
  9. Membrane microdomains are crucial for Mycobacterium marinum EsxA-dependent membrane damage, escape to the cytosol and infection

    This article has 6 authors:
    1. Cristina Bosmani
    2. Angélique Perret
    3. Florence Leuba
    4. Aurélie Guého
    5. Nabil Hanna
    6. Thierry Soldati

    Reviewed by Review Commons

    This article has 4 evaluationsAppears in 1 listLatest version Latest activity
  10. Intestinal fibroblast heterogeneity: unifying RNA-seq studies and introducing consensus-driven nomenclature

    This article has 5 authors:
    1. Neda Glisovic
    2. Aleksandra Chikina
    3. Noémie Robil
    4. Sonia Lameiras
    5. Danijela Matic Vignjevic

    Reviewed by Review Commons

    This article has 3 evaluationsAppears in 1 listLatest version Latest activity
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