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10.1101/2025.04.23.647902
The Rab7-Epg5 and Rab39-ema modules cooperatively position autophagosomes for efficient lysosomal fusions

This article has 10 authors:
1. Attila Boda
2. Villő Balázs
3. Anikó Nagy
4. Dávid Hargitai
5. Mónika Lippai
6. Zsófia Simon-Vecsei
7. Márton Molnár
8. Fanni Fürstenhoffer
9. Gábor Juhász
10. Péter Lőrincz
This article has been curated by 1 group:
- Curated by eLife
  
  eLife Assessment
  
  This paper presents valuable findings on how autophagosomes are positioned along microtubules for their efficient fusion with lysosomes, providing significant insights into the mechanism. The evidence supporting the conclusions is solid, with high-quality fluorescence microscopy combined with Drosophila genetics. This work will be of broad interest to cell biologists interested in autophagy and related cell biology fields.
Reviewed by eLife

This article has 10 evaluationsAppears in 1 listLatest version Oct 28, 2025Latest activity Sep 24, 2025
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Cell Biology

The Rab7-Epg5 and Rab39-ema modules cooperatively position autophagosomes for efficient lysosomal fusions

Curated by eLife