Bioengineering

Human skeletal muscle organoids model fetal myogenesis and sustain uncommitted PAX7 myogenic progenitors

1. Lampros Mavrommatis
2. Hyun-Woo Jeong
3. Urs Kindler
4. Gemma Gomez-Giro
5. Marie-Cecile Kienitz
6. Martin Stehling
7. Olympia E Psathaki
8. Dagmar Zeuschner
9. M Gabriele Bixel
10. Dong Han
11. Gabriela Morosan-Puopolo
12. Daniela Gerovska
13. Ji Hun Yang
14. Jeong Beom Kim
15. Marcos J Arauzo-Bravo
16. Jens C Schwamborn
17. Stephan A Hahn
18. Ralf H Adams
19. Hans R Schöler
20. Matthias Vorgerd
21. Beate Brand-Saberi
22. Holm Zaehres

• Curated by eLife

  eLife assessment

  The authors develop a cell culture system for studies of muscle tissue development and homeostasis. They convincingly validate a novel 3D cell model. Their thorough molecular and functional characterization will make this useful for future workers in the field.

Reviewed by eLife

Acidic Nanoparticles Restore Lysosomal Acidification and Rescue Metabolic Dysfunction in Pancreatic β-Cells under Lipotoxic Conditions

1. Chih Hung Lo
2. Lance M. O’Connor
3. Gavin Wen Zhao Loi
4. Eka Norfaishanty Saipuljumri
5. Jonathan Indajang
6. Kaitlynn M. Lopes
7. Orian S. Shirihai
8. Mark W. Grinstaff
9. Jialiu Zeng

Reviewed by PREreview

Production of extracellular polymeric substances in granular sludge under selection for Accumulibacter and Competibacter

1. Lorena B. Guimarães
2. Nina R. Gubser
3. Yuemei Lin
4. Jure Zlópasa
5. Simon Felz
6. Sergio Tomás Martínez
7. Mario Pronk
8. Thomas R. Neu
9. Morten K. D. Dueholm
10. Mads Albertsen
11. Rejane H. R. da Costa
12. Per Halkjær Nielsen
13. Mark C. M. van Loosdrecht
14. David G. Weissbrodt

Reviewed by Arcadia Science

Bio-friendly long-term subcellular dynamic recording by self-supervised image enhancement microscopy

1. Guoxun Zhang
2. Xiaopeng Li
3. Yuanlong Zhang
4. Xiaofei Han
5. Xinyang Li
6. Jinqiang Yu
7. Boqi Liu
8. Jiamin Wu
9. Li Yu
10. Qionghai Dai

Reviewed by Arcadia Science

Precise transcript targeting by CRISPR-Csm complexes

1. David Colognori
2. Marena Trinidad
3. Jennifer A. Doudna

Reviewed by Arcadia Science

Quantifying the relationship between spreading depolarization and perivascular cerebrospinal fluid flow

1. Saikat Mukherjee
2. Mahsa Mirzaee
3. Jeffrey Tithof

Reviewed by Arcadia Science

An in vitro model for vitamin A transport across the human blood–brain barrier

1. Chandler B Est
2. Regina M Murphy

• Curated by eLife

  eLife assessment

  This fundamental work substantially advances our understanding of retinol transport through the blood-brain barrier. The evidence supporting the conclusions is compelling, with rigorous biochemical assays. In general, the work is of broad interest to cell biologists, biochemists and neuroscientists.

Reviewed by eLife

One-step rapid quantification of SARS-CoV-2 virus particles via low-cost nanoplasmonic sensors in generic microplate reader and point-of-care device

1. Liping Huang
2. Longfei Ding
3. Jun Zhou
4. Shuiliang Chen
5. Fang Chen
6. Chen Zhao
7. Jianqing Xu
8. Wenjun Hu
9. Jiansong Ji
10. Hao Xu
11. Gang L. Liu

Reviewed by ScreenIT

Targeted intracellular degradation of SARS-CoV-2 via computationally optimized peptide fusions

1. Pranam Chatterjee
2. Manvitha Ponnapati
3. Christian Kramme
4. Alexandru M. Plesa
5. George M. Church
6. Joseph M. Jacobson

Reviewed by ScreenIT

Synergistic effects of anionic surfactants on coronavirus (SARS-CoV-2) virucidal efficiency of sanitizing fluids to fight COVID-19

1. Reza Jahromi
2. Vahid Mogharab
3. Hossein Jahromi
4. Arezoo Avazpour

Reviewed by ScreenIT