Evaluated articles

Evaluation of Machine Learning-Assisted Directed Evolution Across Diverse Combinatorial Landscapes

1. Francesca-Zhoufan Li
2. Jason Yang
3. Kadina E. Johnston
4. Emre Gürsoy
5. Yisong Yue
6. Frances H. Arnold

Reviewed by Arcadia Science

Biophysical limits of ultrafast cellular motility

1. Ray Chang
2. Manu Prakash

Reviewed by Arcadia Science

Genetic predisposition towards multicellularity in Chlamydomonas reinhardtii

1. I-Chen Kimberly Chen
2. Shania Khatri
3. Matthew D. Herron
4. Frank Rosenzweig

Reviewed by Arcadia Science

BioFunctional: A Comprehensive App for Interpreting and Visualizing Functional Analysis of KEGG Pathways and Gene Ontologies

1. Alejandro Rodriguez
2. Antonio Monleon Getino

Reviewed by Arcadia Science

FLIMPA: A versatile software for Fluorescence Lifetime Imaging Microscopy Phasor Analysis

1. Sofia Kapsiani
2. Nino F. Läubli
3. Edward N. Ward
4. Mona Shehata
5. Clemens F. Kaminski
6. Gabriele S. Kaminski Schierle

Reviewed by Arcadia Science

Establishing the green algae Chlamydomonas incerta as a platform for recombinant protein production

1. Kalisa Kang
2. Évellin do Espirito Santo
3. Crisandra Jade Diaz
4. Aaron Oliver
5. Lisa Saxton
6. Lauren May
7. Stephen Mayfield
8. João Vitor Dutra Molino

Reviewed by Arcadia Science

Generative Models Validation via Manifold Recapitulation Analysis

1. Nicolo’ Lazzaro
2. Gianluca Leonardi
3. Raffaele Marchesi
4. Massimiliano Datres
5. Anna Saiani
6. Jacopo Tessadori
7. Alejandro Granados
8. Johan Henriksson
9. Marco Chierici
10. Giuseppe Jurman
11. Toma Tebaldi
12. Gabriele Sales

Reviewed by Arcadia Science

Multi-color fluorescence live-cell imaging in Dictyostelium discoideum

1. Hidenori Hashimura
2. Satoshi Kuwana
3. Hibiki Nakagwa
4. Kenichi Abe
5. Tomoko Adachi
6. Toyoko Sugita
7. Shoko Fujishiro
8. Gen Honda
9. Satoshi Sawai

Reviewed by Arcadia Science

Phosphorylation regulated conformational diversity and topological dynamics of an intrinsically disordered nuclear receptor

1. Vasily Akulov
2. Alba Jiménez Panizo
3. Eva Estébanez-Perpiñá
4. John van Noort
5. Alireza Mashaghi

Reviewed by Arcadia Science

InteracTor: A new integrative feature extraction toolkit for improved characterization of protein structural properties

1. Jose Cleydson F. Silva
2. Layla Schuster
3. Nick Sexson
4. Matias Kirst
5. Marcio F. R. Resende
6. Raquel Dias

Reviewed by Arcadia Science

Evaluation of tick salivary and midgut extracellular vesicles as anti-tick vaccines in White-tailed deer ( Odocoileus virginianus )

1. Julia Gonzalez
2. Cristina Harvey
3. Cárita de Souza Ribeiro-Silva
4. Brenda Leal-Galvan
5. Kelly A. Persinger
6. Pia U. Olafson
7. Tammi L. Johnson
8. Adela Oliva Chavez

Reviewed by Arcadia Science

Unveiling the Functional Connectivity of Astrocytic Networks with AstroNet, a Graph Reconstruction Algorithm Coupled to Image Processing

1. L. Zonca
2. F.C. Bellier
3. G. Milior
4. P. Aymard
5. J. Visser
6. A. Rancillac
7. N. Rouach
8. D. Holcman

Reviewed by Arcadia Science

Trim7 does not have a role in the restriction of murine norovirus infection in vivo

1. Mridula Annaswamy Srinivas
2. Linley R. Pierce
3. Mikayla C. Olson
4. Shelly J. Roberston
5. Gail L. Sturdevant
6. Sonja M. Best
7. Robert C. Orchard

Reviewed by Arcadia Science

Mast cells promote pathology and susceptibility in tuberculosis

1. Ananya Gupta
2. Vibha Taneja
3. Javier Rangel Moreno
4. Abhimanyu
5. Mushtaq Ahmed
6. Nilofer Naqvi
7. Kuldeep S Chauhan
8. Daniela Trejo-Ponce de León
9. Gustavo Ramírez-Martínez
10. Luis Jiménez-Alvarez
11. Cesar Luna-Rivero
12. Joaquin Zuniga
13. Deepak Kaushal
14. Shabaana A Khader

• Curated by eLife

  eLife Assessment

  In this useful study, the authors use published scRNA-seq data to highlight the importance of mast cells (MCs) in TB granulomas, reporting a comparative assessment of chymase- and tryptase-expressing MCs in the lungs of tuberculosis-infected individuals and non-human primates, with MC-deficient mice showing reduced lung bacterial burden and pathology during infection. Whilst the findings are helpful, the evidence to support conclusions is inconsistent across models and thus incomplete. Specifically, the data supporting a role for MCs in coordinating cytokine responses to modulate pathology, susceptibility to tuberculosis, and dissemination during infection are weak.

Reviewed by eLife, Arcadia Science

Population genomics reveals strong impacts of genetic drift without purging and guides conservation of bull and giant kelp

1. Jordan B. Bemmels
2. Samuel Starko
3. Brooke L. Weigel
4. Kaede Hirabayashi
5. Alex Pinch
6. Cassandra Elphinstone
7. Megan N. Dethier
8. Loren H. Rieseberg
9. Jonathan E. Page
10. Christopher J. Neufeld
11. Gregory L. Owens

Reviewed by Arcadia Science

Cigarette smoke impairs the endocytotic process in Saccharomyces cerevisiae

1. Aditya Shukla
2. Srimonti Sarkar
3. Alok Kumar Sil

Reviewed by Arcadia Science

BFVD - a large repository of predicted viral protein structures

1. Rachel Seongeun Kim
2. Eli Levy Karin
3. Martin Steinegger

Reviewed by Arcadia Science

Mechanical Centrosome Fracturing during Cell Navigation

1. Madeleine T. Schmitt
2. Mauricio J.A. Ruiz-Fernandez
3. Kasia Stefanowski
4. Janina Kroll
5. Robert Hauschild
6. Jack Merrin
7. Thomas Penz
8. Eva Kiermaier
9. Christoph Bock
10. Tobias Straub
11. Jörg Renkawitz

Reviewed by Arcadia Science

An automated microfluidic platform for toxicity testing based on Caenorhabditis elegans

1. Jiaying Wu
2. Jing Xi
3. Zhouhai Zhu
4. Wei Zhao
5. Qiyuan Peng
6. Chunbo Liu
7. Ziqian Wan
8. Yiyi Cao
9. Xiang Chen
10. Yang Luan

Reviewed by Arcadia Science

Microgravity and low muon radiation affect viral pathogenesis and physiology in Caenorhabditis elegans

1. Ana Villena-Giménez
2. Victoria G. Castiglioni
3. Esmeralda G. Legarda
4. Juan C. Muñoz-Sánchez
5. Rubén González
6. Santiago F. Elena

Reviewed by Arcadia Science