Evaluated articles

Abnormal behavior is reversible in a chromatin mutant

1. Juan D. Rodriguez
2. Monica N. Reeves
3. Hsiao-Lin V. Wang
4. Jaely Z. Chavez
5. Rhea Rastogi
6. Sindy R. Chavez
7. Elicia A Preston
8. Madhav S. Chadha
9. Liyang Sun
10. Emily J. Hill
11. Victor G. Corces
12. Karen L. Schmeichel
13. John I. Murray
14. David J. Katz

Reviewed by Arcadia Science

cellPLATO: an unsupervised method for identifying cell behaviour in heterogeneous cell trajectory data

1. Michael J. Shannon
2. Shira E. Eisman
3. Alan R. Lowe
4. Tyler Sloan
5. Emily M. Mace

Reviewed by Arcadia Science

Exploring the genetic architecture of ecophysiological traits in microbial ecology using statistical analysis of the properties of protein sequences: application to the glycogen accumulating organism (GAO) phenotype

1. Rohan B. H. Williams
2. Irina Bessarab
3. Michael J. Wise
4. Krithika Arumugam

Reviewed by Arcadia Science

Sophocarpine inhibits TRP channels to produce anti-pruritic and analgesic effects in a mouse model of inflammatory itch and pain

1. Hekun Zeng
2. Peiyang Li
3. Dan Zhou
4. Zhe Zhang
5. Alexei Verkhratsky
6. Hong Nie

Reviewed by Arcadia Science

Actin-based deformations of the nucleus control multiciliated ependymal cell differentiation

1. Marianne Basso
2. Alexia Mahuzier
3. Syed Kaabir Ali
4. Anaïs Marty
5. Marion Faucourt
6. Ana-Maria Lennon-Duménil
7. Ayush Srivastava
8. Michella Khoury Damaa
9. Alexia Bankole
10. Alice Meunier
11. Ayako Yamada
12. Julie Plastino
13. Nathalie Spassky
14. Nathalie Delgehyr

Reviewed by preLights, Arcadia Science

Venom diversity in Naja mossambica : Insights from proteomic and immunochemical analyses reveal intraspecific differences

1. Konrad K. Hus
2. Justyna Buczkowicz
3. Monika Pietrowska
4. Vladimír Petrilla
5. Monika Petrillová
6. Jaroslav Legáth
7. Thea Litschka-Koen
8. Aleksandra Bocian

Reviewed by Arcadia Science

Microtubule reorganization during mitotic cell division in the dinoflagellate Ostreospis cf. ovata

1. David Velasquez-Carvajal
2. Flavie Garampon
3. Rodolphe Lemée
4. Sebastian Schaub
5. Stefania Castagnetti

Reviewed by Arcadia Science

Rational Prediction of PROTAC-Compatible Protein–Protein Interfaces by Molecular Docking

1. Gilberto P. Pereira
2. Brian Jiménez-García
3. Riccardo Pellarin
4. Guillaume Launay
5. Sangwook Wu
6. Juliette Martin
7. Paulo C. T. Souza

Reviewed by Arcadia Science

Tunneling nanotubes enable intercellular transfer in zebrafish embryos

1. Olga Korenkova
2. Shiyu Liu
3. Inès Prlesi
4. Anna Pepe
5. Shahad Albadri
6. Filippo Del Bene
7. Chiara Zurzolo

Reviewed by Arcadia Science

An Ultrasensitive Genetically Encoded Voltage Indicator Uncovers the Electrical Activity of Non‐Excitable Cells

1. Philipp Rühl
2. Anagha G. Nair
3. Namrata Gawande
4. Sassrika N. C. W. Dehiwalage
5. Lukas Münster
6. Roland Schönherr
7. Stefan H. Heinemann

Reviewed by Arcadia Science

Zero-shot learning enables instant denoising and super-resolution in optical fluorescence microscopy

1. Chang Qiao
2. Yunmin Zeng
3. Quan Meng
4. Xingye Chen
5. Haoyu Chen
6. Tao Jiang
7. Rongfei Wei
8. Jiabao Guo
9. Wenfeng Fu
10. Huaide Lu
11. Di Li
12. Yuwang Wang
13. Hui Qiao
14. Jiamin Wu
15. Dong Li
16. Qionghai Dai

Reviewed by Arcadia Science

Two-Photon Targeted, Quad Whole-Cell Patch-Clamping Robot

1. Gema I Vera Gonzalez
2. Phatsimo O Kgwarae
3. Simon R Schultz

Reviewed by Arcadia Science

Capitella teleta gets left out: Possible evolutionary shift causes loss of left tissues rather than increased neural tissue from dominant-negative BMPR1

1. Nicole B. Webster
2. Néva P. Meyer

Reviewed by Arcadia Science

Bsp1, a fungal CPI motif protein, regulates actin filament capping in endocytosis and cytokinesis

1. Daniel R. Hummel
2. Markku Hakala
3. Christopher P. Toret
4. Marko Kaksonen

Reviewed by Arcadia Science

The embryonic role of juvenile hormone in the firebrat, Thermobia domestica, reveals its function before its involvement in metamorphosis

1. James W Truman
2. Lynn M Riddiford
3. Barbora Konopova
4. Marcela Nouzova
5. Fernando G Noriega
6. Michelle Herko

• Curated by eLife

  eLife assessment

  This important study presents findings regarding the role of Juvenile Hormone in development and cell differentiation in the ametabolous insect Thermobia domestica, providing an in-depth analysis of JH's roles in a member of this basally branching group. The evidence supporting the claims of the authors is convincing, drawing on a broad range of approaches and variety of experimental techniques. While the interpretation of this work in the wider context - its relevance for the evolution of metamorphosis - is in some places somewhat speculative, the work will be of interest to evolutionary developmental biologists studying the evolution of metamorphosis, and the evolution of insects in general.

Reviewed by eLife, Arcadia Science

A phylogenetic method linking nucleotide substitution rates to rates of continuous trait evolution

1. Patrick Gemmell
2. Timothy B. Sackton
3. Scott V. Edwards
4. Jun S. Liu

Reviewed by Arcadia Science

Molecular de-extinction of antibiotics enabled by deep learning

1. Fangping Wan
2. Marcelo D. T. Torres
3. Jacqueline Peng
4. Cesar de la Fuente-Nunez

Reviewed by Arcadia Science

The commensal protist Tritrichomonas musculus exhibits a dynamic life cycle that induces extensive remodeling of the gut microbiota

1. Ana Popovic
2. Eric Yixiao Cao
3. Joanna Han
4. Nirvana Nursimulu
5. Eliza V.C. Alves-Ferreira
6. Kyle Burrows
7. Andrea Kennard
8. Noor Alsmadi
9. Michael E. Grigg
10. Arthur Mortha
11. John Parkinson

Reviewed by Arcadia Science

Discovery of a new activator of Slack potassium channels with robust efficacy in models of histamine-independent and chronic itch

1. Annika Balzulat
2. W. Felix Zhu
3. Cathrin Flauaus
4. Victor Hernandez-Olmos
5. Jan Heering
6. Sunesh Sethumadhavan
7. Mariam Dubiel
8. Annika Frank
9. Amelie Menge
10. Maureen Hebchen
11. Katharina Metzner
12. Ruirui Lu
13. Robert Lukowski
14. Peter Ruth
15. Stefan Knapp
16. Susanne Müller
17. Dieter Steinhilber
18. Inga Hänelt
19. Holger Stark
20. Ewgenij Proschak
21. Achim Schmidtko

Reviewed by Arcadia Science

Diverse prey capture strategies in teleost larvae

1. Duncan S Mearns
2. Sydney A Hunt
3. Martin W Schneider
4. Ash V Parker
5. Manuel Stemmer
6. Herwig Baier

• Curated by eLife

  eLife Assessment

  This important body of work uses state-of-the-art quantitative methods to characterize and compare behaviors across five different fish species to understand which features are conserved and which ones are differentiated. The convincing results from this study will be of interest to ethologists and also have potential utility in understanding the neural mechanisms leading to these behaviors.

Reviewed by eLife, Arcadia Science