Showing page 21 of 38 pages of list content

  1. Mast cell activation disrupts interactions between endothelial cells and pericytes during early life allergic asthma

    This article has 16 authors:
    1. Régis Joulia
    2. Franz Puttur
    3. Helen Stölting
    4. William J. Traves
    5. Lewis J. Entwistle
    6. Anastasia Voitovich
    7. Minerva Garcia MartĂ­n
    8. May Al-Sahaf
    9. Katie Bonner
    10. Elizabeth Scotney
    11. Philip L. Molyneaux
    12. Richard J. Hewitt
    13. Simone A. Walker
    14. Laura Yates
    15. Sejal Saglani
    16. Clare M. Lloyd

    Reviewed by Arcadia Science

    This article has 8 evaluationsAppears in 1 listLatest version Latest activity
  2. Evolution of novel sensory organs in fish with legs

    This article has 11 authors:
    1. Corey A.H. Allard
    2. Amy L. Herbert
    3. Stephanie P. Krueger
    4. Qiaoyi Liang
    5. Brittany L. Walsh
    6. Andrew L. Rhyne
    7. Allex N. Gourlay
    8. Agnese Seminara
    9. Maude W. Baldwin
    10. David M. Kingsley
    11. Nicholas W. Bellono

    Reviewed by Arcadia Science

    This article has 2 evaluationsAppears in 1 listLatest version Latest activity
  3. Recording Îł-secretase activity in living mouse brains

    This article has 9 authors:
    1. Steven S Hou
    2. Yuya Ikegawa
    3. Yeseo Kwon
    4. Natalia Wieckiewicz
    5. Mei CQ Houser
    6. Brianna Lundin
    7. Brian J Bacskai
    8. Oksana Berezovska
    9. Masato Maesako
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      Hou and colleagues describe the the use of a previously characterized FRET sensor for use in determining gamma secretase activity in the brain of living mice. In an approach that targeted the sensor to neurons, they observe patterns of fluorescent sensor readout suggesting clustered regions of secretase activity. These results once validated would be valuable in the field of Alzheimer's Disease research, yet further validation of the approach is required, as the current evidence provided is inadequate to support the conclusions.

    Reviewed by eLife, Arcadia Science

    This article has 20 evaluationsAppears in 2 listsLatest version Latest activity
  4. Staphylococcus aureus counters organic acid anion-mediated inhibition of peptidoglycan cross-linking through robust alanine racemase activity

    This article has 11 authors:
    1. Sasmita Panda
    2. Yahani P Jayasinghe
    3. Dhananjay D Shinde
    4. Emilio Bueno
    5. Amanda Stastny
    6. Blake P Bertrand
    7. Sujata S Chaudhari
    8. Tammy Kielian
    9. Felipe Cava
    10. Donald R Ronning
    11. Vinai C Thomas
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      In this useful study, the authors present convincing evidence linking the enzyme D-alanine-D-alanine ligase (Ddl), crucial for cell wall fortification, to organic acid exposure in Staphylococcus aureus. While it's established that organic acids impede bacterial growth, the researchers reveal a novel coping mechanism where S. aureus maintains elevated levels of D-alanine, the substrate for Ddl, to counteract this inhibition. This discovery illuminates a bacterial strategy for organic acid tolerance, offering new insights for microbiologists and potentially informing future antimicrobial approaches.

    Reviewed by eLife, Arcadia Science

    This article has 8 evaluationsAppears in 3 listsLatest version Latest activity
  5. Revealing global stoichiometry conservation architecture in cells from Raman spectral patterns

    This article has 6 authors:
    1. Ken-ichiro F Kamei
    2. Koseki J Kobayashi-Kirschvink
    3. Takashi Nozoe
    4. Hidenori Nakaoka
    5. Miki Umetani
    6. Yuichi Wakamoto
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      This paper reports the fundamental finding of how Raman spectral patterns correlate with proteome profiles. The authors then go further to show that this can be used to infer global stochiometric regulation of the proteomes. These findings are likely general and the authors provide compelling evidence by analyzing bacterial and human cells but there are some suggestions provided below to make the work clearer and more accessible for it to reach a broader audience.

    Reviewed by eLife, Arcadia Science

    This article has 5 evaluationsAppears in 2 listsLatest version Latest activity
  6. Phylogenomics reveals coincident divergence between giant host sea anemones and the clownfish adaptive radiation

    This article has 16 authors:
    1. Aurelien De Jode
    2. Andrea M. Quattrini
    3. Tommaso Chiodo
    4. Marymegan Daly
    5. Catherine S. McFadden
    6. Michael L. Berumen
    7. Christopher P. Meyer
    8. Suzanne Mills
    9. Ricardo Beldade
    10. Aaron Bartholomew
    11. Anna Scott
    12. James D Reimer
    13. Kensuke Yanagi
    14. Takuma Fuji
    15. EstefanĂ­a RodrĂ­guez
    16. Benjamin M. Titus

    Reviewed by Arcadia Science

    This article has 7 evaluationsAppears in 1 listLatest version Latest activity