Evaluated articles

Direct inference of the distribution of fitness effects of spontaneous mutations from recombinant inbred C. elegans mutation accumulation lines

1. Timothy A. Crombie
2. Moein Rajaei
3. Ayush S. Saxena
4. Lindsay M. Johnson
5. Sayran Saber
6. Robyn E. Tanny
7. José Miguel Ponciano
8. Erik C. Andersen
9. Juannan Zhou
10. Charles F. Baer

Reviewed by Arcadia Science

Ciliary biology intersects autism and congenital heart disease

1. Nia Teerikorpi
2. Kate E. McCluskey
3. Ethel Bader
4. Micaela C. Lasser
5. Sheng Wang
6. Catherine H. Nguyen
7. James D. Schmidt
8. Elina Kostyanovskaya
9. Nawei Sun
10. Jeanselle Dea
11. Tomasz J. Nowakowski
12. A. Jeremy Willsey
13. Helen Rankin Willsey

Reviewed by Arcadia Science

The Rich Evolutionary History of the Reactive Oxygen Species Metabolic Arsenal Shapes Its Mechanistic Plasticity at the Onset of Metazoan Regeneration

1. Aurore Vullien
2. Aldine R Amiel
3. Loeiza Baduel
4. Dilara Diken
5. Cécile Renaud
6. Gabriel Krasovec
7. Michel Vervoort
8. Eric Röttinger
9. Eve Gazave

Reviewed by Arcadia Science

Development of a highly active engineered PETase enzyme for polyester degradation

1. Shapla Bhattacharya
2. Rossella Castagna
3. Hajar Estiri
4. Toms Upmanis
5. Andrea Ricci
6. Alfonso Gautieri
7. Emilio Parisini

Reviewed by Arcadia Science

Rapid protein evolution by few-shot learning with a protein language model

1. Kaiyi Jiang
2. Zhaoqing Yan
3. Matteo Di Bernardo
4. Samantha R. Sgrizzi
5. Lukas Villiger
6. Alisan Kayabolen
7. Byungji Kim
8. Josephine K. Carscadden
9. Masahiro Hiraizumi
10. Hiroshi Nishimasu
11. Jonathan S. Gootenberg
12. Omar O. Abudayyeh

Reviewed by Arcadia Science

Programming Aliphatic Polyester Degradation by Engineered Bacterial Spores

1. Ziyu Cui
2. Masamu Kawada
3. Yue Hui
4. Seunghyun Sim

Reviewed by Arcadia Science

Competition and cooperation: The plasticity of bacterial interactions across environments

1. Josephine Solowiej-Wedderburn
2. Jennifer T. Pentz
3. Ludvig Lizana
4. Bjoern O. Schroeder
5. Peter A. Lind
6. Eric Libby

Reviewed by Arcadia Science

Cell type-specific immune regulation under symbiosis in a facultatively symbiotic coral

1. Maria Valadez-Ingersoll
2. Hanny E Rivera
3. Jeric Da-Anoy
4. Matthew R Kanke
5. Kelly Gomez-Campo
6. M Isabel Martinez Rugerio
7. Sebastian Metz
8. Michael Sweet
9. Julian Kwan
10. Ryan Hekman
11. Andrew Emili
12. Thomas D Gilmore
13. Sarah W Davies

Reviewed by Arcadia Science

Slowest possible replicative life at frigid temperatures for yeast

1. Diederik S. Laman Trip
2. Théo Maire
3. Hyun Youk

Reviewed by Arcadia Science

Multiple protein structure alignment at scale with FoldMason

1. Cameron L. M. Gilchrist
2. Milot Mirdita
3. Martin Steinegger

Reviewed by Arcadia Science

Macroscopic label-free biomedical imaging with shortwave infrared Raman scattering

1. Bernardo A. Arús
2. Joycelyn Yiu
3. Jakob G. P. Lingg
4. Anja Hofmann
5. Amy R. Fumo
6. Honglei Ji
7. Carolin Jethwa
8. Roy K. Park
9. James Henderson
10. Kanuj Mishra
11. Iuliia Mukha
12. Andre C. Stiel
13. Donato Santovito
14. Christian Weber
15. Christian Reeps
16. Maria Rohm
17. Alexander Bartelt
18. Tulio A. Valdez
19. Andriy Chmyrov
20. Oliver T. Bruns

Reviewed by Arcadia Science

Genomic localization bias of secondary metabolite gene clusters and association with histone modifications in Aspergillus

1. Xin Zhang
2. Iseult Leahy
3. Jérȏme Collemare
4. Michael F. Seidl

Reviewed by Arcadia Science

Secondary metabolite profiling of Pseudomonas aeruginosa isolates reveals rare genomic traits

1. Rachel L. Neve
2. Emily Giedraitis
3. Madeline S. Akbari
4. Shirli Cohen
5. Vanessa V. Phelan

Reviewed by Arcadia Science

Experimental bleaching of photosymbiotic amoeba revealed strain-dependent differences in algal symbiosis ability

1. Daisuke Yamagishi
2. Ryo Onuma
3. Sachihiro Matsunaga
4. Shin-ya Miyagishima
5. Shinichiro Maruyama

Reviewed by Arcadia Science

Amidase and lysozyme dual functions in TseP reveal a new family of chimeric effectors in the type VI secretion system

1. Zeng-Hang Wang
2. Ying An
3. Ting Zhao
4. Tong-Tong Pei
5. Dora Yuping Wang
6. Xiaoye Liang
7. Wenming Qin
8. Tao Dong

• Curated by eLife

  eLife Assessment

  This important study describes how a single effector of the Type Six Secretion System (T6SS) has two distinct functions, which may contribute to bacterial survival and the development of novel antibacterials. The authors utilized various methods in biochemistry, microbiology, and microscopy to produce convincing data supporting their claims about the protein's function; however, they could clarify the implications for non-experts to enhance the accessibility of this work. This manuscript is of interest to those studying T6SS, particularly those interested in effectors and bacterial enzymes.

Reviewed by eLife, Arcadia Science

Effective structure-aware protein alignment via residue-level contrastive learning

1. Ronghui You
2. Ziye Wang
3. Kunpeng Liu
4. Wei Zheng
5. Qiqige Wuyun
6. Yuhao Yi
7. Shanfeng Zhu

Reviewed by Arcadia Science

Inference of Gene Regulatory Networks for Overcoming Low Performance in Real-World Data

1. Yusuke Hiki
2. Yuta Tokuoka
3. Takahiro G. Yamada
4. Akira Funahashi

Reviewed by Arcadia Science

Protein Set Transformer: a protein-based genome language model to power high-diversity viromics

1. Cody Martin
2. Anthony Gitter
3. Karthik Anantharaman

Reviewed by Arcadia Science

Lepidopteran scale cells derive from sensory organ precursors through a canonical lineage

1. Ling S. Loh
2. Kyle A. DeMarr
3. Martina Tsimba
4. Christa Heryanto
5. Alejandro Berrio
6. Nipam H. Patel
7. Arnaud Martin
8. W. Owen McMillan
9. Gregory A. Wray
10. Joseph J. Hanly

Reviewed by Arcadia Science

Peptide-enabled ribonucleoprotein delivery for CRISPR engineering (PERC) in primary human immune cells and hematopoietic stem cells

1. Srishti U. Sahu
2. Madalena Castro
3. Joseph J. Muldoon
4. Kunica Asija
5. Stacia K. Wyman
6. Netravathi Krishnappa
7. Lorena de Oñate
8. Justin Eyquem
9. David N. Nguyen
10. Ross C. Wilson

Reviewed by Arcadia Science