Latest Irish Research & Discoveries

Interpretation of murine models of cardiac disease is enhanced by consideration of divergently expressed human-mouse orthologous genes

1. Oisín Cappa
2. Chris Watson
3. David Simpson

A genetic perspective on the recent demographic history of Ireland and Britain

1. Ashwini Shanmugam
2. Michael Merrigan
3. Seamus O’Reilly
4. Anne M. Molloy
5. Lawrence Brody
6. Orla Hardiman
7. Russell McLaughlin
8. Gianpiero L. Cavalleri
9. Ross Byrne
10. Edmund Gilbert

Multiperiod vaccination facility planning

1. Grace Tacadao
2. Helmut Simonis
3. Luis Quesada
4. Barry O'Sullivan

Study Protocol- The impact of social deprivation on development and progression of diabetic kidney disease

1. Caoimhe Casey
2. Claire M Buckley
3. Patricia M Kearney
4. Matthew D Griffin
5. Sean F Dinneen
6. Tomás P Griffin

Exploring the sugar-sweetened beverage tax (SSBT) pass-through rate in the Irish hospitality sector

1. Frank Houghton
2. J. Moran Stritch
3. J. Auerbach
4. M. Daly
5. D. Houghton

Oysters, a sustainable bluefood?

1. Paula Costa Domech
2. Ronan Cooney
3. Alexandre Tahar
4. Alan Kennedy
5. Alex H L Wan
6. Eoghan Clifford

The gut microbiome associated with LGI1- and CASPR2-antibody encephalitis

1. Edmund Gilbert
2. Sophie Binks
3. Valentina Damato
4. Christopher Uy
5. Paula Colmenero
6. Mohamed Ibrahim Khalil
7. Marcus O’Brien
8. Marcus Claesson
9. John F Cryan
10. Norman Delanty
11. Sarosh R Irani
12. Gianpiero L Cavalleri

Weather window analysis for the deployment, operation, and maintenance of marine renewable energy devices in Irish coastal waters

1. Dylan Moore
2. Alireza Eftekhari
3. Stephen Nash

A positive feedback loop between germ cells and gonads induces and maintains cnidarian sexual reproduction

1. Camille Curantz
2. Ciara Doody
3. Helen R Horkan
4. Gabriel Krasovec
5. Paris K Weavers
6. Timothy Q DuBuc
7. Uri Frank

Developing Consensus for an Upper and Lower Limb Athlete Pain Assessment Framework – A Real-time Delphi Study with International Sports Physiotherapists

1. Ciarán Purcell
2. Brona M Fullen
3. Tomás Ward
4. Brian M Caulfield

Rising Clindamycin Resistance in Group A Streptococcus in an Irish Healthcare Institution

1. Susan Lapthorne
2. Robert McWade
3. Nuala Scanlon
4. Saoirse Ní Bhaoill
5. Aoife Page
6. Clare O'Donnell
7. Gabriela Dornikova
8. Margaret Hannan
9. Breda Lynch
10. Maureen Lynch
11. Deirdre Brady

Inhibitors of methane (CH4 ) producing bacteria: Development of hydrolysates and fermentates from brown seaweeds and identification of biomolecules with enteric CH4 abatement potential

1. Goldy Bhowmick
2. Dilip K. Rai
3. Oyenike Olatunji
4. Kieran Kilcawley
5. Iwona Skibinska
6. E. Shannon
7. Deirdre Kennedy
8. Desmond Walsh
9. Leticia Mora
10. Maria Hayes

Natural forgetting reversibly modulates engram expression

1. James D O’Leary
2. Rasmus Bruckner
3. Livia Autore
4. Tomás J Ryan

• Curated by eLife

  eLife assessment

  This is an important paper on the role of engrams and relevant conditions that influence memory and forgetting. The variety of methods used, namely, behavioural, labeling, interrogation, immunohistochemistry, microscopy, pharmacology, computational, are exemplary and provide convincing evidence for the role of engrams in the dentate gyrus in memory retrieval and forgetting. This examination will be of interest broadly across behavioural and neural science communities.

Reviewed by eLife

Dominant negative effects on H3K27 methylation by Weaver syndrome-associated EZH2 variants

1. Orla Deevy
2. Craig Monger
3. Francesca Matrà
4. Ellen Tuck
5. Eric Conway
6. Mihaly Badonyi
7. Darragh Nimmo
8. Simona Rodighiero
9. Qi Zhang
10. Chen Davidovich
11. Joseph A. Marsh
12. Diego Pasini
13. Adrian P. Bracken

Reviewed by PREreview

Prior probability cues bias sensory encoding with increasing task exposure

1. Kevin Walsh
2. David P McGovern
3. Jessica Dully
4. Simon P Kelly
5. Redmond G O'Connell

• Curated by eLife

  eLife assessment

  This important paper sheds light on the role of expectations in perceptual decision-making. Sophisticated analyses of human EEG data provide convincing evidence that both motor preparation and sensory processing were affected by expectations, albeit with different time courses. These findings will be of interest to scientists interested in perception and decision-making.

Reviewed by eLife

Iron Is Critical for Mucosal-Associated Invariant T Cell Metabolism and Effector Functions

1. Eimear K. Ryan
2. Christy Clutter
3. Conor De Barra
4. Benjamin J. Jenkins
5. Simon O’Shaughnessy
6. Odhrán K. Ryan
7. Chloe McKenna
8. Helen M. Heneghan
9. Fiona Walsh
10. David K. Finlay
11. Linda V. Sinclair
12. Nicholas Jones
13. Daniel T. Leung
14. Donal O’Shea
15. Andrew E. Hogan

Iron deficiency in people with obesity drives defective Natural Killer cell mitochondrial fitness and function

1. Conor De Barra
2. Eimear Ryan
3. Michelle Sugrue
4. Odhran Ryan
5. Evelyn Lynn
6. Helen M. Heneghan
7. Cormac McCarthy
8. Paul N. Moynagh
9. Linda V. Sinclair
10. Nicholas Jones
11. Andrew E. Hogan
12. Donal O’Shea

Human coronavirus 229E infection inactivates pyroptosis executioner gasdermin D but ultimately leads to lytic cell death partly mediated by gasdermin E

1. Xavier Martiáñez-Vendrell
2. Jonna Bloeme
3. Roy Hutchinson
4. Coralie Guy
5. Andrew Bowie
6. Marjolein Kikkert

Treatment with lipoxin A4 improves influenza A infection outcome, induces macrophage reprogramming, anti-inflammatory and pro-resolutive responses

1. Flavia Rago
2. Eliza Mathias Melo
3. Leigh M. Miller
4. Alexis M. Duray
5. Franciel Batista Felix
6. Juliana Priscila Vago
7. Ana Paula de Faria Gonçalves
8. Ana Luiza Pessoa Mendonça Angelo
9. Geovanni D. Cassali
10. Monica de Gaetano
11. Eoin Brennan
12. Benjamin Owen
13. Patrick Guiry
14. Catherine Godson
15. John F. Alcorn
16. Mauro Martins Teixeira

Ancient genomics reveals a genetic continuum with dual structure in the Classic Copan

1. Madeleine Murray
2. Seiichi Nakamura
3. Melvin Fuentes
4. Masahiro Ogawa
5. Lara M. Cassidy
6. Takashi Gakuhari
7. Shigeki Nakagome