Reading List

Temperature Sensitive Glutamate Gating of AMPA-subtype iGluRs

1. Anish Kumar Mondal
2. Elisa Carrillo
3. Vasanthi Jayaraman
4. Edward C. Twomey

Resolving the conformational ensemble of a membrane protein by integrating small-angle scattering with AlphaFold

1. Samuel Eriksson Lidbrink
2. Rebecca J. Howard
3. Nandan Haloi
4. Erik Lindahl

Multiple LPA3 Receptor Agonist Binding Sites Evidenced Under Docking and Functional Studies

1. K. Helivier Solís
2. M. Teresa Romero-Ávila
3. Ruth Rincón-Heredia
4. Sergio Romero-Romero
5. José Correa-Basurto
6. J. Adolfo García-Sáinz

Transport of herbicides by PIN-FORMED auxin transporters

1. Lukas Schulz
2. Kien Lam Ung
3. Sarah Koutnik-Abele
4. David L Stokes
5. Bjørn Panyella Pedersen
6. Ulrich Z. Hammes

Molecular Insights into Single-Chain Lipid Modulation of Acid-Sensing Ion Channel 3

1. Ramya Bandarupalli
2. Rebecca Roth
3. Robert C Klipp
4. John R Bankston
5. Jing Li

Reviewed by Arcadia Science

Structural basis of inhibition of human NaV1.8 by the tarantula venom peptide Protoxin-I

1. Bryan Neumann
2. Stephen McCarthy
3. Shane Gonen

Diarylamidine activation of a brachiopod DEG/ENaC/ASIC channel

1. Josep Martí-Solans
2. Aina Børve
3. Andreas Hejnol
4. Timothy Lynagh

Comparative analysis of STP6 and STP10 unravels molecular selectivity in sugar transport proteins

1. Camilla Gottlieb Andersen
2. Laust Bavnhøj
3. Søren Brag
4. Anastasiia Bohush
5. Adriana Chrenková
6. Jan Heiner Driller
7. Bjørn Panyella Pedersen

High-resolution structures of the UapA purine transporter reveal unprecedented aspects of the elevator-type transport mechanism

1. George Broutzakis
2. Yiannis Pyrris
3. Ifigeneia Akrani
4. Alexander Neuhaus
5. Emmanuel Mikros
6. George Diallinas
7. Christos Gatsogiannis

Mammalian PIEZO channels rectify anionic currents

1. Tharaka D. Wijerathne
2. Aashish Bhatt
3. Wenjuan Jiang
4. Yun L. Luo
5. Jerome J. Lacroix

Structural basis of phosphate export by human XPR1

1. Qixian He
2. Ran Zhang
3. Sandrine Tury
4. Valérie Courgnaud
5. Fenglian Liu
6. Jean-luc Battini
7. Baobin Li
8. Qingfeng Chen

Atomic-Level Free Energy Landscape Reveals Cooperative Symport Mechanism of Melibiose Transporter

1. Ruibin Liang
2. Lan Guan

• Curated by eLife

  eLife Assessment

  In this potentially important study, the authors employed advanced computational techniques to explore a detailed atomistic description of the mechanism and energetics of substrate translocation in the MelB transporter. The overall approach is solid and reveals the coupling between sodium binding and melibiose transport through a series of conformational transitions, and the results for a mutant are also in qualitative agreement with the experiment, providing further support to the computational analyses. Nevertheless, the level of evidence is considered incomplete since there are concerns regarding the convergence and initial guess of the string calculations, leaving doubts that the computed pathway does not reflect the most energetically favorable mechanism.

Reviewed by eLife

Cryo‐EM structures of multiple‐peptide resistance factor ( MprF ) from Pseudomonas aeruginosa

1. Shaileshanand Jha
2. Kutti R. Vinothkumar

Reviewed by Review Commons

MAASTY: a (dis)ordered copolymer for structural determination of human membrane proteins in native nanodiscs

1. Ciara F. Pugh
2. Lukas P. Feilen
3. Dušan Živković
4. Kaia F. Præstegaard
5. Charalampos Sideris
6. Neil J. Borthwick
7. Casper de Lichtenberg
8. Jani R. Bolla
9. Anton A. A. Autzen
10. Henriette E. Autzen

Finding the E-channel proton loading sites by calculating the ensemble of protonation microstates

1. Md. Raihan Uddin
2. Umesh Khaniya
3. Chitrak Gupta
4. Junjun Mao
5. Gehan A. Ranepura
6. Rongmei Judy Wei
7. Jose Ortiz-Soto
8. Abhishek Singharoy
9. M.R. Gunner

Nernst equilibrium, rectification, and saturation: Insights into ion channel behavior

1. Ryan Carlsen
2. Hannah Weckel-Dahman
3. Jessica M.J. Swanson

A range of voltage-clamp protocol designs for rapid capture of hERG kinetics

1. Chon Lok Lei
2. Dominic J Whittaker
3. Monique J Windley
4. Matthew D Perry
5. Adam P Hill
6. Gary R Mirams

Functional investigation of a putative calcium-binding site involved in the inhibition of inositol 1,4,5-trisphosphate receptor activity

1. Vikas Arige
2. Larry E. Wagner
3. Sundeep Malik
4. Mariah R. Baker
5. Guizhen Fan
6. Irina I. Serysheva
7. David I. Yule

Aerolysin Nanopore Structures Revealed at High Resolution in a Lipid Environment

1. Jana S. Anton
2. Ioan Iacovache
3. Juan F. Bada Juarez
4. Luciano A. Abriata
5. Louis W. Perrin
6. Chan Cao
7. Maria J. Marcaida
8. Benoît Zuber
9. Matteo Dal Peraro