ScreenIT

Latest preprint reviews

1. The unmitigated profile of COVID-19 infectiousness

   This article has 6 authors:

   1. Ron Sender
   2. Yinon Bar-On
   3. Sang Woo Park
   4. Elad Noor
   5. Jonathan Dushoff
   6. Ron Milo

   This article has been curated by 1 group:

   • Curated by eLife

     Evaluation Summary:

     A pathogen's generation interval directly affects estimates of its transmissibility (R), and the period of self-isolation or quarantine needed to prevent transmission. This study shows that the unmitigated generation interval of the original variant of SARS-CoV-2 is several days longer than previously estimated and that interventions have substantially decreased the effective generation interval. These findings improve our ability to model counterfactual intervention-free scenarios. Overall technically sound analyses support the conclusions, and extensive sensitivity analyses show that the findings are robust. However, sampling or ascertainment bias in this relatively small pre-intervention dataset or biased inputs could affect the accuracy of the reported estimates.

     (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #3 agreed to share their name with the authors.)

   Reviewed by eLife, ScreenIT

2. Germinal centre-driven maturation of B cell response to SARS-CoV-2 vaccination

   This article has 21 authors:

   1. Wooseob Kim
   2. Julian Q. Zhou
   3. Alexandria J. Sturtz
   4. Stephen C. Horvath
   5. Aaron J. Schmitz
   6. Tingting Lei
   7. Elizaveta Kalaidina
   8. Mahima Thapa
   9. Wafaa B. Alsoussi
   10. Alem Haile
   11. Michael K. Klebert
   12. Teresa Suessen
   13. Luis Parra-Rodriguez
   14. Philip A. Mudd
   15. William D. Middleton
   16. Sharlene A. Teefey
   17. Iskra Pusic
   18. Jane A. O’Halloran
   19. Rachel M. Presti
   20. Jackson S. Turner
   21. Ali H. Ellebedy

   Reviewed by ScreenIT

3. Multiple spillovers from humans and onward transmission of SARS-CoV-2 in white-tailed deer

   This article has 18 authors:

   1. Suresh V. Kuchipudi
   2. Meera Surendran-Nair
   3. Rachel M. Ruden
   4. Michele Yon
   5. Ruth H. Nissly
   6. Kurt J. Vandegrift
   7. Rahul K. Nelli
   8. Lingling Li
   9. Bhushan M. Jayarao
   10. Costas D. Maranas
   11. Nicole Levine
   12. Katriina Willgert
   13. Andrew J. K. Conlan
   14. Randall J. Olsen
   15. James J. Davis
   16. James M. Musser
   17. Peter J. Hudson
   18. Vivek Kapur

   Reviewed by ScreenIT

4. Global Mutational Sweep of SARS-CoV-2: From Chaos to Order

   This article has 8 authors:

   1. Xin Wang
   2. Mingda Hu
   3. Yuan Jin
   4. Boqian Wang
   5. Yunxiang Zhao
   6. Long Liang
   7. Junjie Yue
   8. Hongguang Ren

   Reviewed by ScreenIT

5. Modelling the response to vaccine in non-human primates to define SARS-CoV-2 mechanistic correlates of protection

   This article has 23 authors:

   1. Marie Alexandre
   2. Romain Marlin
   3. Mélanie Prague
   4. Severin Coleon
   5. Nidhal Kahlaoui
   6. Sylvain Cardinaud
   7. Thibaut Naninck
   8. Benoit Delache
   9. Mathieu Surenaud
   10. Mathilde Galhaut
   11. Nathalie Dereuddre-Bosquet
   12. Mariangela Cavarelli
   13. Pauline Maisonnasse
   14. Mireille Centlivre
   15. Christine Lacabaratz
   16. Aurelie Wiedemann
   17. Sandra Zurawski
   18. Gerard Zurawski
   19. Olivier Schwartz
   20. Rogier W Sanders
   21. Roger Le Grand
   22. Yves Levy
   23. Rodolphe Thiébaut

   This article has been curated by 1 group:

   • Curated by eLife

     Evaluation Summary:

     This work should be of interest to a broad readership in infectious diseases, especially those people interested in modeling of infections. It combines statistical and mechanistic modeling to find assayable correlates of immunity for vaccines. This method could be relevant to many diseases or vaccines, although the particular markers identified here likely will be limited in their generalizability.

     (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. The reviewers remained anonymous to the authors.)

   Reviewed by eLife, ScreenIT

6. Profiling RT-LAMP tolerance of sequence variation for SARS-CoV-2 RNA detection

   This article has 3 authors:

   1. Esta Tamanaha
   2. Yinhua Zhang
   3. Nathan A. Tanner

   Reviewed by ScreenIT

7. Predicting SARS-CoV-2 epitope-specific TCR recognition using pre-trained protein embeddings

   This article has 2 authors:

   1. Youngmahn Han
   2. Aeri Lee

   Reviewed by ScreenIT

8. Coronavirus RNA Synthesis Takes Place within Membrane-Bound Sites

   This article has 4 authors:

   1. Nicole Doyle
   2. Jennifer Simpson
   3. Philippa C. Hawes
   4. Helena J. Maier

   Reviewed by ScreenIT

9. SARS-CoV-2 triggered excessive inflammation and abnormal energy metabolism in gut microbiota

   This article has 18 authors:

   1. Tuoyu Zhou
   2. Yufei Zeng
   3. Jingyuan Wu
   4. Junfeng Li
   5. Jun Yan
   6. Wenbo Meng
   7. Hawen Han
   8. Fengya Feng
   9. Jufang He
   10. Shuai Zhao
   11. Ping Zhou
   12. Ying Wu
   13. Yanling Yang
   14. Rong Han
   15. Weiling Jin
   16. Xun Li
   17. Yunfeng Yang
   18. Xiangkai Li

   Reviewed by ScreenIT

10. Variations in Cell Surface ACE2 Levels Alter Direct Binding of SARS-CoV-2 Spike Protein and Viral Infectivity: Implications for Measuring Spike Protein Interactions with Animal ACE2 Orthologs

    This article has 6 authors:

    1. Soheila Kazemi
    2. Alberto Domingo López-Muñoz
    3. Jaroslav Hollý
    4. Ling Jin
    5. Jonathan W. Yewdell
    6. Brian P. Dolan

    Reviewed by ScreenIT