ScreenIT

Latest preprint reviews

1. Comprehensive fitness landscape of SARS-CoV-2 Mpro reveals insights into viral resistance mechanisms

   This article has 9 authors:

   1. Julia M Flynn
   2. Neha Samant
   3. Gily Schneider-Nachum
   4. David T Barkan
   5. Nese Kurt Yilmaz
   6. Celia A Schiffer
   7. Stephanie A Moquin
   8. Dustin Dovala
   9. Daniel NA Bolon

   This article has been curated by 1 group:

   • Curated by eLife

     Evaluation Summary:

     The main protease of SARS-CoV-2 (Mpro) is a leading target for drug design due to its conserved and indispensable role in the life cycle. This study used cutting-edge molecular and statistical methods to generate a detailed genotype-phenotype map of this protein, also called a "fitness landscape." This fitness landscape is impressive in its detail and resolution and offers new insight that can be used to potentially generate new anti-viral drugs. This study was original in conception, precise in execution, and impressive in design. In sum, this constitutes a very meaningful addition to scientific literature.

     (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #1 and Reviewer #2 agreed to share their name with the authors.)

   Reviewed by eLife, ScreenIT

2. Anti-SARS-CoV-2 swine glyco-humanized polyclonal antibody XAV-19 retains neutralizing activity against SARS-CoV-2 B.1.1.529 (Omicron)

   This article has 15 authors:

   1. Bernard Vanhove
   2. Stéphane Marot
   3. Gwénaëlle Evanno
   4. Isabelle Malet
   5. Gaëtane Rouvray
   6. Françoise Shneiker
   7. Edwige Mevel
   8. Carine Ciron
   9. Juliette Rousse
   10. Pierre-Joseph Royer
   11. Elsa Lheriteau
   12. François Raffi
   13. Odile Duvaux
   14. Anne-Geneviève Marcelin
   15. Vincent Calvez

   Reviewed by ScreenIT

3. Structural diversity of the SARS-CoV-2 Omicron spike

   This article has 25 authors:

   1. Sophie M.-C. Gobeil
   2. Rory Henderson
   3. Victoria Stalls
   4. Katarzyna Janowska
   5. Xiao Huang
   6. Aaron May
   7. Micah Speakman
   8. Esther Beaudoin
   9. Kartik Manne
   10. Dapeng Li
   11. Rob Parks
   12. Maggie Barr
   13. Margaret Deyton
   14. Mitchell Martin
   15. Katayoun Mansouri
   16. Robert J. Edwards
   17. Amanda Eaton
   18. David C. Montefiori
   19. Gregory D. Sempowski
   20. Kevin O. Saunders
   21. Kevin Wiehe
   22. Wilton Williams
   23. Bette Korber
   24. Barton F. Haynes
   25. Priyamvada Acharya

   Reviewed by ScreenIT

4. Comparative immunogenicity of heterologous versus homologous 3rd SARS-CoV-2 vaccine doses in kidney transplant recipients

   This article has 16 authors:

   1. Tina Thomson
   2. Maria Prendecki
   3. Sarah Gleeson
   4. Paul Martin
   5. Katrina Spensley
   6. Charlotte Seneschall
   7. Jaslyn Gan
   8. Candice L. Clarke
   9. Shanice Lewis
   10. Graham Pickard
   11. David Thomas
   12. Stephen P. McAdoo
   13. Liz Lightstone
   14. Alison Cox
   15. Peter Kelleher
   16. Michelle Willicombe

   Reviewed by PREreview, ScreenIT

5. Seroepidemiological and genomic investigation of COVID-19 spread in North East region of India

   This article has 19 authors:

   1. Romi Wahengbam
   2. Pankaj Bharali
   3. Prasenjit Manna
   4. Tridip Phukan
   5. Moirangthem Goutam Singh
   6. Gayatri Gogoi
   7. Yasmin Begam Tapadar
   8. Anil Kumar Singh
   9. Rituraj Konwar
   10. Channakeshavaiah Chikkaputtaiah
   11. Natarajan Velmurugan
   12. Selvaraman Nagamani
   13. Hridoy Jyoti Mahanta
   14. Himakshi Sarma
   15. Ravi Kumar Sahu
   16. Prachurjya Dutta
   17. Sawlang Borsingh Wann
   18. Jatin Kalita
   19. G Narahari Sastry

   Reviewed by ScreenIT

6. Comparison of Vaccine Effectiveness Against the Omicron (B.1.1.529) Variant in Hemodialysis Patients

   This article has 14 authors:

   1. Katrina J. Spensley
   2. Sarah Gleeson
   3. Paul Martin
   4. Tina Thomson
   5. Candice L. Clarke
   6. Graham Pickard
   7. David Thomas
   8. Stephen P. McAdoo
   9. Paul Randell
   10. Peter Kelleher
   11. Rachna Bedi
   12. Liz Lightstone
   13. Maria Prendecki
   14. Michelle Willicombe

   Reviewed by ScreenIT

7. Comparative diagnostic performance of the new chromatographic Affimer ^® -based rapid antigen detection against SARS-CoV-2 and other standard antigen tests for COVID-19 in a clinical setting

   This article has 7 authors:

   1. A.I. Gil-Garcia
   2. A. Lopez-Lopez
   3. J.M. Rubio
   4. J.J. Montoya
   5. Y. Ouahid
   6. A. Madejon
   7. P. Castan

   Reviewed by ScreenIT

8. Assessment of Neutralizing Antibody Response Against SARS-CoV-2 Variants After 2 to 3 Doses of the BNT162b2 mRNA COVID-19 Vaccine

   This article has 7 authors:

   1. Koichi Furukawa
   2. Lidya Handayani Tjan
   3. Yukiya Kurahashi
   4. Silvia Sutandhio
   5. Mitsuhiro Nishimura
   6. Jun Arii
   7. Yasuko Mori

   Reviewed by ScreenIT

9. Adverse events following COVISHIELD (ChAdOx1nCoV-19) vaccination among health care workers in Sri Lanka; a multi-centre cross sectional survey

   This article has 17 authors:

   1. S.R. Manilgama
   2. N.M. Hettiarachchi
   3. I.K. Jayasinghe
   4. S.T. De Silva
   5. T. Jayalath
   6. T. Wanigaratne
   7. R.P. Bandusiri
   8. N. Suganthan
   9. P. Sudarshan
   10. M. Pathirage
   11. N. Rajaratnam
   12. G. Senaratne
   13. V. Rajapaksha
   14. A. Wickramasinghe
   15. S.P.A.L. Ranaweera
   16. H.M.A. Thilakarathna
   17. M.T.D. Kulaweera

   Reviewed by ScreenIT

10. Neutralizing immunity in vaccine breakthrough infections from the SARS-CoV-2 Omicron and Delta variants

    This article has 24 authors:

    1. Venice Servellita
    2. Abdullah M. Syed
    3. Mary Kate Morris
    4. Noah Brazer
    5. Prachi Saldhi
    6. Miguel Garcia-Knight
    7. Bharath Sreekumar
    8. Mir M. Khalid
    9. Alison Ciling
    10. Pei-Yi Chen
    11. G. Renuka Kumar
    12. Amelia S. Gliwa
    13. Jenny Nguyen
    14. Alicia Sotomayor-Gonzalez
    15. Yueyuan Zhang
    16. Edwin Frias
    17. John Prostko
    18. John Hackett
    19. Raul Andino
    20. Debra A. Wadford
    21. Carl Hanson
    22. Jennifer Doudna
    23. Melanie Ott
    24. Charles Y. Chiu

    Reviewed by ScreenIT