eLife

Latest preprint reviews

1. Megabouts: a flexible pipeline for zebrafish locomotion analysis

   This article has 9 authors:

   1. Adrien Jouary
   2. Pedro TM Silva
   3. Alexandre Laborde
   4. J Miguel Mata
   5. João C Marques
   6. Elena MD Collins
   7. Randall T Peterson
   8. Christian K Machens
   9. Michael B Orger

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This study introduces Megabouts, a transformer-based classifier for larval zebrafish movement bouts. This useful tool is thoughtfully implemented and has clear potential to unify analyses across labs. However, the evidence supporting its robustness is incomplete. How the method generalizes across datasets, how sensitive it is to noise, and the specific sources of misclassification are unclear. The method would also be strengthened by providing options for users to fine-tune the clusters under different experimental conditions, which would further enhance reliability and flexibility.

   Reviewed by eLife

2. We couldn't get details of this article at this time:
   10.1101/2025.08.19.671164

3. We couldn't get details of this article at this time:
   10.1101/2025.07.28.667319

4. We couldn't get details of this article at this time:
   10.1101/2025.06.02.657382

5. We couldn't get details of this article at this time:
   10.1101/2025.01.15.633288

6. We couldn't get details of this article at this time:
   10.1101/2025.09.18.677143

7. Endogenous Real Time Imaging Reveals Dynamic Chromosomal Mobility During Ligand-Mediated Transcriptional Burst Events

   This article has 11 authors:

   1. Susan Wang
   2. Thomas Suter
   3. Amir Gamliel
   4. Yeeun Kim
   5. Sreejith J Nair
   6. Soohwan Oh
   7. Feng Yang
   8. Kenneth A Ohgi
   9. Tobias Wagner
   10. Steven Gan
   11. Michael G Rosenfeld

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This manuscript presents significant and important work that advances single-molecule imaging technology of transcription with simultaneous analysis of several parameters. However, currently, the evidence is incomplete and requires further quantitation/description of the technologies used, further controls, and additional analysis of the data by other methods.

   Reviewed by eLife

8. We couldn't get details of this article at this time:
   10.1101/2025.04.18.649578

9. Molecular Architecture and Function Mechanism of Tri-heteromeric GluN1-N2-N3A NMDA Receptors

   This article has 7 authors:

   1. Zengwei Kou
   2. Fenyong Yao
   3. Tongtong Zhang
   4. Nan Song
   5. Chun Xie
   6. Boshuang Wang
   7. Yidi Sun

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This important work advances our understanding of NMDAR diversity in the brain by providing evidence into the subunit arrangement, architecture, and activation mechanism of GluN1-N2-N3A tri-NMDAR. However, the evidence supporting the conclusions provides incomplete proof for the presence and functional properties of this NMDA receptor subtype. The work will be of broad interest to neuroscientists and biophysicists.

   Reviewed by eLife

10. We couldn't get details of this article at this time:
    10.1101/2025.05.26.25328345