eLife

Latest preprint reviews

1. How Occam’s razor guides human decision-making

   This article has 5 authors:

   1. Eugenio Piasini
   2. Shuze Liu
   3. Pratik Chaudhari
   4. Vijay Balasubramanian
   5. Joshua I Gold

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This study presents an important new approach to quantifying parsimony preferences in human inference. The work provides convincing evidence that humans are sensitive to specific formalizations of parsimony, such as the dimensionality of perceptual shapes. The work is considered timely, well-written, and technically sophisticated, effectively bridging concepts from statistical inference and human decision-making.

   Reviewed by eLife

2. EEG decodability of facial expressions and their stereoscopic depth cues in immersive virtual reality

   This article has 7 authors:

   1. Felix Klotzsche
   2. Ammara Nasim
   3. Simon M Hofmann
   4. Arno Villringer
   5. Vadim Nikulin
   6. Werner Sommer
   7. Michael Gaebler

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This valuable study successfully decoded visual representations of facial expressions and stereoscopic depth information from electroencephalogram (EEG) signals recorded in an immersive virtual reality (VR) environment. The evidence is solid in demonstrating the technical feasibility of integrating state-of-the-art EEG decoding and VR with eye tracking. This work will interest neuroscience researchers, as well as engineers developing brain-machine interfaces and/or virtual reality displays.

   Reviewed by eLife

3. Persistent contacts between Climp63 and microtubules cause mitotic defects and nuclear fragmentation

   This article has 2 authors:

   1. Jelmi uit de Bos
   2. Ulrike Kutay

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This important study reveals that mitotic release of an ER-microtubule tether is critical for normal mitotic progression. Manipulating CLIMP63 phosphorylation, the authors provide convincing evidence that persistent microtubule-ER contacts activate the spindle assembly checkpoint and, if mitosis is forced to proceed, drive severe micronucleation. While the study provides new mechanistic insights, some evidence is indirect, and additional experiments would further refine the model.

   Reviewed by eLife

4. We couldn't get details of this article at this time:
   10.1101/2025.08.27.672541

5. We couldn't get details of this article at this time:
   10.1101/2025.08.21.671527

6. We couldn't get details of this article at this time:
   10.1101/2025.08.01.668093

7. We couldn't get details of this article at this time:
   10.1101/2025.01.21.633929

8. We couldn't get details of this article at this time:
   10.1101/2025.09.03.673942

9. Atovaquone/proguanil use and zoster vaccination are associated with reduced Alzheimer’s disease risk in two cohorts: implications for a latent Toxoplasma gondii mechanism

   This article has 7 authors:

   1. Ariel Israel
   2. Abraham Weizman
   3. Sarah Israel
   4. Shai Ashkenazi
   5. Shlomo Vinker
   6. Eli Magen
   7. Eugene Merzon

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This useful study raises interesting questions but provides inadequate evidence of an association between atovaquone-proguanil use (as well as toxoplasmosis seropositivity) and reduced Alzheimer's dementia risk. The findings are intriguing but they are correlative and hypothesis-generating with the strong possibility of residual confounding.

     [Note: The final version has been published in Brain, Behavior, and Immunity: https://doi.org/10.1016/j.bbi.2026.106473]

   Reviewed by eLife

10. Serratia marcescens Outer Membrane Vesicles rapidly paralyze Drosophila melanogaster through triggering apoptosis in the nervous system

    This article has 11 authors:

    1. Bechara Sina Rahme
    2. Roberto E Bruna
    3. Marion Draheim
    4. Chuping Cai
    5. Maria Victoria Molino
    6. Yaotang Wu
    7. Miriam Wennida Yamba
    8. Gisela Di Venanzio
    9. Matthieu Lestradet
    10. Eleonora García Véscovi
    11. Dominique Ferrandon

    This article has been curated by 1 group:

    • Curated by eLife

      eLife Assessment

      This study offers important insights into how outer membrane vesicles (OMVs) secreted by Serratia marcescens, which carry various virulence factors, contribute to pathogenicity. The experiments provide solid preliminary support for OMV-mediated pathogenic effects, with a critical role for the metalloprotease virulence factor PrtA. However, the evidence remains incomplete, and the current level of validation limits confidence in the strength of the conclusions.

    Reviewed by eLife