eLife

Latest preprint reviews

1. We couldn't get details of this article at this time:
   10.1101/2025.11.12.687966

2. We couldn't get details of this article at this time:
   10.1101/2025.11.04.686631

3. Multi-Scale Anti-Correlated Neural States Dominate Naturalistic Whole-Brain Activity

   This article has 4 authors:

   1. Dora Gözükara
   2. Djamari Oetringer
   3. Nasir Ahmad
   4. Linda Geerligs

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This manuscript presents a novel investigation of organizational principles governing brain activity at both global and local scales during naturalistic viewing paradigms, an important advance for theoretical neuroscience, functional neuroimaging, and neurology. The authors demonstrate that brain activity during naturalistic viewing is dominated by two anti-correlated states that toggle between each other with a third transitional state mediating between them. The evidence supporting this finding is compelling, with the successful replication across three independent datasets (StudyForrest, NarrattenTion, and CamCAN) a particular strength.

   Reviewed by eLife

4. Improved sensory representations as a result of temporal adaptation

   This article has 5 authors:

   1. Amber Marijn Brands
   2. Zilan Oz
   3. Nikolina Vukšić
   4. Paulo Ortiz
   5. Iris Isabelle Anna Groen

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This valuable study examined how sensory adaptation supports visual perception in the presence of noise. The authors used a combination of human psychophysics, electroencephalography (EEG), and deep neural networks to show that adaptation to noise can improve perception. The results are solid but are, at present, weakened by a number of concerns, including some related to the experimental design and some regarding the interpretation of the results in terms of particular mechanisms. With these concerns adequately addressed, the study and conclusions would be likely to be of broad interest to the neuroscience community.

   Reviewed by eLife

5. We couldn't get details of this article at this time:
   10.64898/2025.12.02.691784

6. Conformational Changes of the ABC Transporter BmrA Depend on Membrane Curvature

   This article has 13 authors:

   1. Alicia Damm
   2. Kemil Belhadji
   3. Raj Kumar Sadhu
   4. Su-Jin Paik
   5. Aurélie Di-Cicco
   6. John Manzi
   7. Michele Castellana
   8. Raju Regmi
   9. Emmanuel Margeat
   10. Maxime Dahan
   11. Pierre Sens
   12. Daniel Lévy
   13. Patricia Bassereau

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This valuable study investigates whether the activity of an ABC transporter, BmrA, can be modulated by mechanical stimuli. The authors develop a single-molecule experimental system to address this question, although aspects of the methodological framework are incomplete. This work also develops a convincing theoretical model to explain the effect of membrane curvature on the conformational transitions observed during the activity cycle of this membrane protein. This study is of interest to the fields of membrane biophysics and membrane transport.

   Reviewed by eLife

7. We couldn't get details of this article at this time:
   10.1101/2025.11.25.690450

8. Bone marrow hemogenic endothelial cells contribute multilineage hematopoietic progenitors in adult mice

   This article has 7 authors:

   1. Jing-Xin Feng
   2. Mei-Ting Yang
   3. Caiyi C. Li
   4. Ferenc Livák
   5. Abdalla Abdelmaksoud
   6. Dunrui Wang
   7. Giovanna Tosato

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     The study proposed hemogenic endothelium in adult BM using lineage tracing. Though the study is potentially valuable, the data is incomplete due to the lack of control and insufficient analysis. There is potential for the study to be improved by further revision.

   Reviewed by eLife

9. FRG1 Regulates Nonsense-Mediated mRNA Decay by Modulating UPF1 Levels

   This article has 7 authors:

   1. Ananya Palo
   2. Talina Mohapatra
   3. Anamika Singh
   4. Shithij Thalakkat
   5. Suryasikha Mohanty
   6. Rajeeb Kumar Swain
   7. Manjusha Dixit

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This useful study by Palo et al proposes that FRG1 functions as a negative regulator of Nonsense-Mediated mRNA decay (NMD) by associating with the exon junction complex (EJC) and destabilizing UPF1 independently of DUX4. The authors present solid evidence to dissect the relationship between FRG1 and DUX4 in NMD. However, the evidence to support the claim that FRG1 is a component of the EJC or the NMD machinery is incomplete.

   Reviewed by eLife

10. We couldn't get details of this article at this time:
    10.1101/2025.10.07.680892