eLife

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1. We couldn't get details of this article at this time:
   10.1101/2024.09.10.612215

2. We couldn't get details of this article at this time:
   10.1101/2024.02.15.580498

3. We couldn't get details of this article at this time:
   10.1101/2022.11.07.515494

4. We couldn't get details of this article at this time:
   10.1101/2022.07.19.500665

5. Predestined neutrophil heterogeneity in homeostasis varies in transcriptional and phenotypic response to Candida

   This article has 16 authors:

   1. Allison K. Scherer
   2. Alex Hopke
   3. Shuying Xu
   4. Adam Viens
   5. Natalie J. Alexander
   6. Kyle D. Timmer
   7. Dakota Archambault
   8. Daniel Floyd
   9. Natalie J. Atallah
   10. Catherine Rhee
   11. Murat Cetinbas
   12. David T. Scadden
   13. Daniel Irimia
   14. David B. Sykes
   15. Ruslan I. Sadreyev
   16. Michael K. Mansour

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     In their study, Scherer and colleagues aim to use analyses of single-cell clones of murine granulocyte monocyte progenitors that are conditionally immortalized, and analyses of neutrophils derived from those clones to characterize an experimental system for studying neutrophil heterogeneity. The multi-omic and functional analyses reported are valuable but the strength of the evidence presented in support of them is incomplete because the study lacks a rigorous demonstration that the neutrophil-like cells that they derive are fully mature neutrophils.

   Reviewed by eLife

6. End-to-end proteogenomics for discovery of cryptic and non-canonical cancer proteoforms using long-read transcriptomics and multi-dimensional proteomics

   This article has 8 authors:

   1. Katarzyna Kulej
   2. Asher Preska Steinberg
   3. Jinxin Zhang
   4. Gabriella Casalena
   5. Eli Havasov
   6. Sohrab P Shah
   7. Andrew McPherson
   8. Alex Kentsis

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This manuscript describes a useful integrated proteogenomics pipeline to enable the discovery of novel peptides in cancer cell lines. The method combines long-read RNA sequencing with a multi-protease digestion and proteomics approach. The method is a further development of the authors' previous approaches to identify cancer-specific peptides; however, the current study focuses on a single cell line, and the characterization remains incomplete and lacks validation for candidate alterations. The manuscript will be of interest to scientists focusing on identifying unique alterations in cancer cells.

   Reviewed by eLife

7. We couldn't get details of this article at this time:
   10.64898/2025.12.31.697193

8. A mediterranean-mimicking diet harnesses gut microbiota–derived 3-IAA to rejuvenate T cell

   This article has 9 authors:

   1. Xin Yu
   2. Wenge Li
   3. Hongfang Feng
   4. Zhiyu Li
   5. Hongmei Zheng
   6. Shengrong Sun
   7. Juanjuan Li
   8. Bei Li
   9. Qi Wu

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This fundamental study advances our understanding of how dietary patterns shape cancer immunity by identifying a link between a Mediterranean-mimicking diet, gut bacteria, and a metabolite that enhances anti-tumor immune responses. The evidence supporting the main conclusions is solid, based on carefully controlled diet experiments, measurements of gut-derived molecules, and functional immune analyses across multiple models, together with supportive observations in human data. The work will be of broad interest to biologists working on microbiota and cancer. However, there are several issues that the authors should address to improve the manuscript.

   Reviewed by eLife

9. We couldn't get details of this article at this time:
   10.1101/2025.11.18.688992

10. Depletion of rRNA Methyltranferase METTL5 Enhances Anti-Tumor Immune Response via Neoantigen Generated from Cryptic Translation

    This article has 8 authors:

    1. Yangyi Zhang
    2. Xiaoyan Shi
    3. Yuci Wang
    4. Ruiqi Wang
    5. Folan Lin
    6. Yanlan Cao
    7. Wanqiu Li
    8. Hao Chen

    This article has been curated by 1 group:

    • Curated by eLife

      eLife Assessment

      This study presents a valuable finding that depletion of the rRNA methyltransferase METTL5 enhances anti-tumor immunity through a novel mechanism involving neoantigen generation from non-canonical translation. The evidence supporting the central conclusions is solid, with comprehensive multi-omics data including ribosome profiling, immunopeptidomics, TCR sequencing, and multiple in vivo tumor models demonstrating synergy with immune checkpoint blockade.

    Reviewed by eLife