Latest preprint reviews

  1. ROM1 is redundant to PRPH2 as a molecular building block of photoreceptor disc rims

    This article has 9 authors:
    1. Tylor R Lewis
    2. Mustafa S Makia
    3. Carson M Castillo
    4. Ying Hao
    5. Muayyad R Al-Ubaidi
    6. Nikolai P Skiba
    7. Shannon M Conley
    8. Vadim Y Arshavsky
    9. Muna I Naash
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      This valuable study is focused on the requirement of the photoreceptor-specific tetraspanins, ROM1 and PRPH2, for the formation of light-sensitive membrane discs. The evidence supporting the claim that deficiency in one of the proteins can be compensated by the other is convincing, with both established and advanced techniques yielding results that will be of interest to those studying photoreceptor development and membrane curvature.

    Reviewed by eLife

    This article has 8 evaluationsAppears in 1 listLatest version Latest activity
  2. The reciprocal regulation between mitochondrial-associated membranes and Notch signaling in skeletal muscle atrophy

    This article has 6 authors:
    1. Yurika Ito
    2. Mari Yamagata
    3. Takuya Yamamoto
    4. Katsuya Hirasaka
    5. Takeshi Nikawa
    6. Takahiko Sato
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      This interesting and important manuscript combines in vitro and in vivo experiments to investigate the reciprocal regulation between mitochondria-associated membranes and Notch signaling in skeletal muscle atrophy, with implications beyond the single subfield of muscle atrophy. The methods, data, and analyses are solid and broadly support the claims.

    Reviewed by eLife

    This article has 7 evaluationsAppears in 1 listLatest version Latest activity
  3. LRRC23 truncation impairs radial spoke 3 head assembly and sperm motility underlying male infertility

    This article has 12 authors:
    1. Jae Yeon Hwang
    2. Pengxin Chai
    3. Shoaib Nawaz
    4. Jungmin Choi
    5. Francesc Lopez-Giraldez
    6. Shabir Hussain
    7. Kaya Bilguvar
    8. Shrikant Mane
    9. Richard P Lifton
    10. Wasim Ahmad
    11. Kai Zhang
    12. Jean-Ju Chung
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      This study provides valuable findings on a causative relationship between LRRC23 mutations and male infertility due to asthenozoospermia. The evidence supporting the conclusions is solid. This work will be of interest to biomedical researchers who work on sperm biology and non-hormonal male contraceptive development.

    Reviewed by eLife

    This article has 7 evaluationsAppears in 1 listLatest version Latest activity
  4. The songbird lateral habenula projects to dopaminergic midbrain and is important for normal vocal development

    This article has 5 authors:
    1. Andrea Roeser
    2. Han Kheng Teoh
    3. Ruidong Chen
    4. Itai Cohen
    5. Jesse Goldberg
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      The authors provide the first investigation of the role of the lateral habenula in vocal learning in the songbird. This study provides important insights into the conserved connectivity of the lateral habenula with dopaminergic reinforcement circuits and presents a potential role of this circuit in zebra finch song learning. The results stem from a careful anatomical and functional mapping and from a rigorous behavior analysis that, together, implicate a previously undescribed analog between mammals and songbirds. Although many aspects of the manuscript - like the analysis of song behavior - are exceptional, the evidence linking behavior to selective lesions of the lateral habenula is, at this point, incomplete, leaving the interpretation of key results difficult.

    Reviewed by eLife

    This article has 3 evaluationsAppears in 1 listLatest version Latest activity
Newer Page 450 of 871 Older