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SUMOylation of Bonus, the Drosophila homolog of Transcription Intermediary Factor 1, safeguards germline identity by recruiting repressive chromatin complexes to silence tissue-specific genes

This article has 4 authors:
1. Baira Godneeva
2. Maria Ninova
3. Katalin Fejes-Toth
4. Alexei Aravin
This article has been curated by 1 group:
- Curated by eLife
  
  eLife assessment
  
  This important study advances our knowledge of Drosophila Bonus, the sole ortholog of the mammalian transcriptional regulator Tif1. Solid evidence, both in vivo and in vitro, shows how SUMOylation controls the function of the Bonus protein and what the impact of SUMOylation on the function of Bonus protein in the ovary is.
Reviewed by eLife

This article has 7 evaluationsAppears in 1 listLatest version Nov 24, 2023Latest activity Nov 10, 2023
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