eLife

Latest preprint reviews

1. CRISPR-Cas9 knockdown of ESR1 in preoptic GABA-kisspeptin neurons suppresses the preovulatory surge and estrous cycles in female mice

   This article has 6 authors:

   1. Jenny Clarkson
   2. Siew Hoong Yip
   3. Robert Porteous
   4. Alexia Kauff
   5. Alison K Heather
   6. Allan E Herbison

   This article has been curated by 1 group:

   • Curated by eLife

     eLife assessment

     This important study provides convincing evidence of the criticality of estradiol – estrogen receptor-mediated upregulation of kisspeptin within neurons of the preoptic area to generate an ovulation-inducing luteinizing hormone surge. The use of in vivo CRIPSR-Cas9 is novel in this system and provides a road map for future studies in reproductive neuroendocrinology. This paper will be of interest to reproductive neuroscientists and endocrinologists.

   Reviewed by eLife

2. We couldn't get details of this article at this time:
   10.1101/2023.07.15.549072

3. We couldn't get details of this article at this time:
   10.1101/2023.06.15.545141

4. We couldn't get details of this article at this time:
   10.1101/2023.05.02.539063

5. We couldn't get details of this article at this time:
   10.1101/2022.04.28.489889

6. We couldn't get details of this article at this time:
   10.1101/2021.10.01.462699

7. We couldn't get details of this article at this time:
   10.1101/2023.08.02.551694

8. We couldn't get details of this article at this time:
   10.1101/2023.07.25.550605

9. Pulsed ultrasound promotes secretion of anti-inflammatory extracellular vesicles from skeletal myotubes via elevation of intracellular calcium level

   This article has 10 authors:

   1. Atomu Yamaguchi
   2. Noriaki Maeshige
   3. Hikari Noguchi
   4. Jiawei Yan
   5. Xiaoqi Ma
   6. Mikiko Uemura
   7. Dongming Su
   8. Hiroyo Kondo
   9. Kristopher Sarosiek
   10. Hidemi Fujino

   This article has been curated by 1 group:

   • Curated by eLife

     eLife assessment

     This study illuminates the effects of ultrasound-induced extracellular vesicle interactions with macrophages. It provides solid data offering insights that will be potentially useful in exploring therapeutic approaches to inflammation modulation, by suggesting that ultrasound-treated myotube vesicles can suppress macrophage inflammatory responses.

   Reviewed by eLife

10. We couldn't get details of this article at this time:
    10.1101/2023.06.02.543249