eLife

Latest preprint reviews

1. The structure of Egalitarian in complex with the K10 mRNA localization signal reveals a modular binding surface required for function

   This article has 4 authors:

   1. Zebin Hong
   2. Li Jin
   3. Jonas Mühle
   4. Fulvia Bono

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This manuscript has convincing data that provides a high-resolution structure of the Egl-RNA complex. The findings are important to understand the formation, stability, and interactions of this complex. However, the manuscript could be improved by conducting a rigorous statistical analysis, a deeper understanding of apparent discrepancies in the stoichiometric Egl-to-RNA ratio, and exploring the specificity of this complex using a more diverse set of control RNAs.

   Reviewed by eLife

2. We couldn't get details of this article at this time:
   10.1101/2025.11.25.690391

3. We couldn't get details of this article at this time:
   10.1101/2025.09.30.679494

4. We couldn't get details of this article at this time:
   10.1101/2024.08.06.606834

5. We couldn't get details of this article at this time:
   10.64898/2026.02.15.706005

6. Reproducible and predictable reorganization of place fields driven by grid subfield rate changes

   This article has 7 authors:

   1. Christine M Lykken
   2. Benjamin R Kanter
   3. Jasmine Kaslow
   4. Oscar MT Chadney
   5. Kadjita Asumbisa
   6. Lucie AL Descamps
   7. Clifford G Kentros

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This study provides a valuable contribution to understanding grid-to-place transformations, offering new insights into the structure and reliability of these representations and extending prior work in a meaningful way. The evidence supporting the authors' conclusions is solid, based on careful analyses and well-executed experiments, although clarity and mechanistic interpretation would be strengthened by improving sample size reporting, expanding population-level analyses, and future studies including simultaneous entorhinal-hippocampal recordings. The work will be of interest to neuroscientists studying spatial coding and hippocampal-entorhinal circuit function.

   Reviewed by eLife

7. Wetness modulates the effects of grazing on net ecosystem productivity in global grasslands

   This article has 14 authors:

   1. Yueqiang Wu
   2. Le Qi
   3. Hao Li
   4. Jiguang Feng
   5. Peng Zhou
   6. Hangyu Li
   7. Xiaoyang Gao
   8. Zhijie Wang
   9. Shilin Cui
   10. Ping Yin
   11. Wenhong Ma
   12. Cunzhu Liang
   13. Zhiyong Li
   14. Biao Zhu

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This study uses convincing modeling methods and analyses of rich behavioral datasets to investigate the role of attention in value-based decision making; for instance, as when choosing between two snacks. The results are valuable, as they challenge existing theories that assume that paying attention to an available option biases the eventual choice toward that option. The results suggest that the correlation between attention and decision-making is formed largely after and not before the (internal) choice process has terminated, a finding that offers an intuitively appealing rethinking of how attention and decision-making processes interact during value-based choices.

   Reviewed by eLife

8. We couldn't get details of this article at this time:
   10.64898/2026.01.10.698805

9. A non-human primate model of Amyotrophic Lateral Sclerosis

   This article has 7 authors:

   1. Rachael HA Jones
   2. Luciano Saieva
   3. Fabien Balezeau
   4. Ian Schofield
   5. Caroline McCardle
   6. Mark R Baker
   7. Stuart N Baker

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This fundamental study provides a major contribution to our understanding of Amyotrophic Lateral Sclerosis (ALS) pathogenesis by utilizing a primate model that overcomes the historical limitations of rodent paradigms. By demonstrating the retrograde and trans-synaptic spread of pathological TDP-43 from the periphery to the spinal cord and motor cortex, the authors propose a new model for the disease spreading. The evidence supporting these findings is compelling, characterized by rigorous post-mortem histological observations. This work will be of profound interest to neuroscientists and translational researchers seeking to decode the mechanisms of systemic disease progression in ALS.

   Reviewed by eLife

10. Method of loci training yields unique prefrontal representations that support effective memory encoding

    This article has 7 authors:

    1. Jingyuan Ren
    2. Boris N Konrad
    3. Yannan Zhu
    4. Fan Li
    5. Michael Czisch
    6. Martin Dresler
    7. Isabella C Wagner

    This article has been curated by 1 group:

    • Curated by eLife

      eLife Assessment

      This study presents a useful array of analyses of the effects of training and/or instruction to use the method of loci during episodic encoding and retrieval. A major strength of the experiment is the impressive recruitment of memory athletes and the training of novice athletes to use the method of loci, long known to improve the precision of memory recall. That said, the sheer number of results and their organization should be addressed; streamlining the results and placing them, whenever possible, in a theoretical framework. As it stands, the presented work is incomplete with respect to the major conclusions that training itself leads to neural differentiation of prefrontal cortical neural patterns, and the authors need to temper these claims.

    Reviewed by eLife