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  1. Core PCP mutations affect short time mechanical properties but not tissue morphogenesis in the Drosophila pupal wing

    This article has 9 authors:
    1. Romina Piscitello-Gómez
    2. Franz S Gruber
    3. Abhijeet Krishna
    4. Charlie Duclut
    5. Carl D Modes
    6. Marko Popović
    7. Frank Jülicher
    8. Natalie A Dye
    9. Suzanne Eaton
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      This valuable study provides a combination of experiment and theory to investigate the role of a key signalling pathway as a patterning guide for local and global mechanical properties in a developing tissue. It poses solid evidence that local dynamical effects are not necessarily predictive of global tissue mechanics, although it does not offer an alternative mechanistic explanation. This multidisciplinary work will likely have an impact on the fields of tissue mechanics and developmental biology.

    Reviewed by eLife

    This article has 4 evaluationsAppears in 1 listLatest version Latest activity
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