eLife

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1. We couldn't get details of this article at this time:
   10.21203/rs.3.rs-1970365/v3

2. We couldn't get details of this article at this time:
   10.1101/2023.10.19.563042

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   10.1101/2023.10.18.562941

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   10.1101/2023.09.06.556513

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   10.1101/2023.08.16.553641

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   10.1101/2023.10.06.561292

7. WASP facilitates tumor mechanosensitivity in T lymphocytes

   This article has 10 authors:

   1. Srishti Mandal
   2. Mariane Melo
   3. Pavlo Gordiichuk
   4. Sayanti Acharya
   5. Yeh-Chuin Poh
   6. Na Li
   7. Aereas Aung
   8. Eric L. Dane
   9. Darrell J. Irvine
   10. Sudha Kumari

   This article has been curated by 1 group:

   • Curated by eLife

     eLife assessment

     This valuable study employs a diverse array of techniques encompassing cell biological manipulations, biophysical measurements, and mouse models to elucidate the impact of target cell stiffness on CD8+ cytotoxic T cell activation, with a particular focus on the actin nucleator protein WASP. The finding that WASP is essential for the stiffness-dependent phosphorylation of ZAP70 in CD8 T cells is convincing. However, the data regarding the role of WASP in mechanosensing within CD8 T cell-mediated anti-tumor immunity is incomplete and would benefit from a more rigorous study design. This work would be of interest to cell biologists and investigators studying mechanosensing within the immune system.

   Reviewed by eLife

8. We couldn't get details of this article at this time:
   10.1101/2023.09.26.559535

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   10.1101/2023.09.17.558100

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    10.1101/2023.06.05.543678