eLife

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1. We couldn't get details of this article at this time:
   10.1101/2023.09.21.558851

2. Knock-down of a regulatory barcode shifts macrophage polarization destination from M1 to M2 and increases pathogen burden upon S. aureus infection

   This article has 6 authors:

   1. Sathyabaarathi Ravichandran
   2. Bharat Bhatt
   3. Awantika Shah
   4. Debajyoti Das
   5. Kithiganahalli Narayanaswamy Balaji
   6. Nagasuma Chandra

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     The authors of this manuscript study the transcriptional regulators that allow macrophages to assume different functional phenotypes in response to immune stimuli. They generate a computational map of the gene regulatory networks involved in determining macrophage phenotypes and experimentally validate the role of putative regulatory factors in a myeloid cell line. This study represents a valuable approach to understanding how gene regulation impacts macrophage polarization and their conclusions are supported by solid computational and experimental evidence. The revision has clarified that the focus is the identification of the regulatory barcodes in a myeloid cell line. Future studies in primary cells and in vivo will be required to assess the roles of these regulators in a broader context.

   Reviewed by eLife

3. The title and authors for this article are not available from our external data provider yet:
   10.31219/osf.io/preprints/psyarxiv

4. We couldn't get details of this article at this time:
   10.1101/2023.09.18.558206

5. We couldn't get details of this article at this time:
   10.1101/2022.11.05.515308

6. We couldn't get details of this article at this time:
   10.1101/2021.11.16.468866

7. We couldn't get details of this article at this time:
   10.1101/2021.07.14.452426

8. We couldn't get details of this article at this time:
   10.1101/2023.10.18.562970

9. We couldn't get details of this article at this time:
   10.1101/2023.10.11.561882

10. MAFB drives differentiation by permitting WT1 binding to podocyte specific promoters

    This article has 11 authors:

    1. Filippo M. Massa
    2. Fariba Jian-Motamedi
    3. Marijus Šerys
    4. Amelie Tison
    5. Agnès Loubat
    6. Sandra Lacas-Gervais
    7. Luc Martin
    8. Hassiba Belahbib
    9. Sandrine Sarrazin
    10. Michael H. Sieweke
    11. Andreas Schedl

    This article has been curated by 1 group:

    • Curated by eLife

      eLife assessment

      This study presents valuable insights into the epigenetic landscape in adult kidney podocytes. A series of solid experiments demonstrate that genes that are regulated by a key kidney transcription factor, Mafb, are essential for H3K4me3 methylation and recruitment of Wt1 to Nphs1 and Nphs2. This new information provides insights into the potential relationship and coordination of transcription factors in regulating target genes in podocytes in glomerular diseases, although the conclusion that MafB is generally required for Wt1 to bind to podocyte-specific promoters is incomplete and should be extended beyond two or three genes.

    Reviewed by eLife