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  1. The seminal odorant binding protein Obp56g is required for mating plug formation and male fertility in Drosophila melanogaster

    This article has 7 authors:
    1. Nora C Brown
    2. Benjamin Gordon
    3. Caitlin E McDonough-Goldstein
    4. Snigdha Misra
    5. Geoffrey D Findlay
    6. Andrew G Clark
    7. Mariana Federica Wolfner
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      This important study describes an atypical role of the odorant binding protein Obp56g in mating plug formation in Drosophila melanogaster suggesting that Obps may play roles in reproduction in addition to their originally described roles in olfaction. Mutant males lacking Obp56g fail to induce the formation of a mating plug in the female reproductive tract-leading to ejaculate loss and reduced sperm storage. The evidence supporting the claims of the authors is solid and compelling. The work will be of interest to biologists studying Obps and seminal fluid protein function and their evolution.

    Reviewed by eLife

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