Latest preprint reviews

  1. Microglia facilitate and stabilize the response to general anesthesia via modulating the neuronal network in a brain region-specific manner

    This article has 15 authors:
    1. Yang He
    2. Taohui Liu
    3. Quansheng He
    4. Wei Ke
    5. Xiaoyu Li
    6. Jinjin Du
    7. Suixin Deng
    8. Zhenfeng Shu
    9. Jialin Wu
    10. Baozhi Yang
    11. Yuqing Wang
    12. Ying Mao
    13. Yanxia Rao
    14. Yousheng Shu
    15. Bo Peng
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      This study presents a valuable finding on the mechanisms underlying general anesthesia, with a focus on microglial regulation. The evidence supporting the claims of the authors is solid, although some of the novelty of these findings may be reduced based on the recent publication of a similar study. The work will be of interest to medical biologists working on mechanisms of anesthesia, microglia, and neuron-microglia interaction.

    Reviewed by eLife

    This article has 5 evaluationsAppears in 1 listLatest version Latest activity
  2. Genome-wide Functional Characterization of Escherichia coli Promoters and Sequence Elements Encoding Their Regulation

    This article has 9 authors:
    1. Guillaume Urtecho
    2. Kimberly D. Insigne
    3. Arielle D. Tripp
    4. Marcia S. Brinck
    5. Nathan B. Lubock
    6. Christopher Acree
    7. Hwangbeom Kim
    8. Tracey Chan
    9. Sriram Kosuri
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      Urtecho et al. use genome-integrated massively parallel reporter assays to catalog and characterize promoters throughout the Escherichia coli genome. The result is a state-of-the-art atlas of promoters, coupled with information on their regulation, that is readily accessible through the website http://ecolipromoterdb.com. This compelling work provides an important resource for researchers studying bacterial transcriptional regulation.

    Reviewed by eLife

    This article has 4 evaluationsAppears in 1 listLatest version Latest activity
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