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   10.1101/2023.10.11.561953

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   10.1101/2023.10.06.561186

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   10.1101/2023.07.27.550829

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   10.1101/2023.11.07.566024

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   10.1101/2023.11.13.566830

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   10.1101/2023.10.30.564746

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   10.1101/2023.10.24.563872

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   10.1101/2023.10.13.562268

9. Interaction of GAT1 with sodium ions: from efficient recruitment to stabilisation of substrate and conformation

   This article has 12 authors:

   1. Erika Lazzarin
   2. Ralph Gradisch
   3. Sophie MC Skopec
   4. Leticia Alves da Silva
   5. Chiara Sebastianelli-Schoditsch
   6. Dániel Szöllősi
   7. Julian Maier
   8. Sonja Sucic
   9. Marko Roblek
   10. Baruch I Kanner
   11. Harald H Sitte
   12. Thomas Stockner

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     The study elucidates a detailed molecular mechanism of the initial stages of transport in the medically relevant Na+-coupled GABA neurotransmitter transporter GAT1 and thus generates important new insights into this protein family. In particular, it presents convincing evidence for the presence of a "staging binding site" that locally concentrates Na+ ions to increase transport activity, whilst solid evidence for how Na+ binding influences larger scale dynamics.

   Reviewed by eLife

10. We couldn't get details of this article at this time:
    10.1101/2023.06.14.544876