eLife

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1. We couldn't get details of this article at this time:
   10.1101/2023.09.08.556854

2. Acyl-CoA thioesterase-2 facilitates β-oxidation in glycolytic skeletal muscle in a lipid supply dependent manner

   This article has 13 authors:

   1. Carmen Bekeova
   2. Ji In Han
   3. Heli Xu
   4. Evan Kerr
   5. Brittney Blackburne
   6. Shannon C. Lynch
   7. Clementina Mesaros
   8. Marta Murgia
   9. Rajanikanth Vadigepalli
   10. Joris Beld
   11. Roberta Leonardi
   12. Nathaniel W. Snyder
   13. Erin L. Seifert

   This article has been curated by 1 group:

   • Curated by eLife

     eLife assessment

     This study presents new data highlighting the importance of appropriate coenzyme A handling in the mitochondria for maintaining appropriate energy production capacity. Several findings regarding the role of a key metabolic enzyme in how skeletal muscle cells use different substrates for energy production are valuable and supported by solid evidence, but there are concerns whether the data support the conclusion that ACOT2 regulates mitochondrial matrix acyl-CoA levels in white skeletal muscle to facilitate fatty acid oxidation β-oxidation.

   Reviewed by eLife

3. We couldn't get details of this article at this time:
   10.1101/2023.10.06.561285

4. We couldn't get details of this article at this time:
   10.1101/2023.09.16.558050

5. We couldn't get details of this article at this time:
   10.1101/2023.10.23.563672

6. We couldn't get details of this article at this time:
   10.1101/2023.09.27.23296204

7. Gcn5 – mTORC1 – TFEB signalling axis mediated control of autophagy regulates Drosophila blood cell homeostasis

   This article has 5 authors:

   1. Arjun Aji Reeja
   2. Mincy Kunjumon
   3. Suraj Math
   4. Laxmi Kata
   5. Rohan Jayant Khadilkar

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This valuable study identifies Gcn5 as a regulator of blood cell development in the Drosophila lymph gland, with links to autophagy and nutrient-sensing mTORC1 signalling. The evidence is solid that altering Gcn5, autophagy genes and mTORC1 activity perturbs blood cell homeostasis, and the revised manuscript adds helpful genetic and quantitative analyses. However, the evidence for a clean linear Gcn5-mTORC1-TFEB/autophagy pathway is insufficient, because several cell-type-specific phenotypes remain difficult to reconcile and the pathway logic relies on different genetic tools, cell populations and pharmacological perturbations.

   Reviewed by eLife

8. We couldn't get details of this article at this time:
   10.1101/2023.07.02.547395

9. We couldn't get details of this article at this time:
   10.1101/2023.11.08.566169

10. A comprehensive neuroanatomical survey of the Drosophila Lobula Plate Tangential Neurons with predictions for their optic flow sensitivity

    This article has 14 authors:

    1. Arthur Zhao
    2. Aljoscha Nern
    3. Sanna Koskela
    4. Marisa Dreher
    5. Mert Erginkaya
    6. Connor W. Laughland
    7. Henrique Ludwigh
    8. Alex Thomson
    9. Judith Hoeller
    10. Ruchi Parekh
    11. Sandro Romani
    12. Davi D. Bock
    13. Eugenia Chiappe
    14. Michael B. Reiser

    This article has been curated by 1 group:

    • Curated by eLife

      eLife assessment

      This important study presents the first comprehensive catalog of the large neurons that compute optic flow in any insect. The morphological reconstructions from volume electron microscopy of the large arbors of these neurons, the Lobula Plate Tangential Neurons, were followed by the examination of their spatial arrangement to estimate their individual receptive fields and predict their optimal motion sensitivity. This compelling, rigorous data set, which includes the synaptic connectivity of the neurons under study with major target neurons in the fly brain, establishes a foundation for future studies on visual processing on the basis of a known connectome plus genetic driver lines to manipulate its constituent neurons. It will be of interest beyond insect vision to those studying sensory processing and neural circuit function.

    Reviewed by eLife