eLife

Latest preprint reviews

1. CEP44 is required for maintaining centriole duplication and spindle integrity

   This article has 9 authors:

   1. Donghui Zhang
   2. Wenlu Wei
   3. Xiaopeng Zou
   4. Hui Meng
   5. Fangyuan Li
   6. Minjun Yao
   7. Junling Teng
   8. Ning Huang
   9. Jianguo Chen

   This article has been curated by 1 group:

   • Curated by eLife

     eLife assessment

     This useful study investigates the role of the centrosomal protein CEP44 in centriole duplication and mitotic spindle formation. While the analysis of CEP44 mitotic phosphorylation and spindle recruitment is solid, the characterization of CEP44's role at centrioles is incomplete and would benefit from additional controls and analyses. Since the work links CEP44 reduced expression to poor survival in breast cancer patients, it is of interest not only to cell biologists but also to cancer researchers.

   Reviewed by eLife

2. We couldn't get details of this article at this time:
   10.1101/2023.11.01.565163

3. We couldn't get details of this article at this time:
   10.1101/2023.10.13.562287

4. We couldn't get details of this article at this time:
   10.1101/2023.05.15.540538

5. We couldn't get details of this article at this time:
   10.1101/2022.08.09.503299

6. The title and authors for this article are not available from our external data provider yet:
   10.48550/arxiv.2302.14157v2

7. Autoacetylation-mediated phase separation of TIP60 is critical for its functions

   This article has 3 authors:

   1. Shraddha Dubey
   2. Himanshu Gupta
   3. Ashish Gupta

   This article has been curated by 1 group:

   • Curated by eLife

     eLife assessment

     This is a valuable study on K187 acetylation of the nuclear protein, TIP60, required for its phase separation and function. The evidence supporting the primary conclusion is incomplete and warrants more scrutiny.

   Reviewed by eLife

8. We couldn't get details of this article at this time:
   10.1101/2023.07.19.549668

9. We couldn't get details of this article at this time:
   10.1101/2023.02.02.526767

10. Analyses of allele age and fitness impact reveal human beneficial alleles to be older than neutral controls

    This article has 5 authors:

    1. Alyssa M. Pivirotto
    2. Alexander Platt
    3. Ravi Patel
    4. Sudhir Kumar
    5. Jody Hey

    This article has been curated by 1 group:

    • Curated by eLife

      eLife assessment

      Drawing on a human population genomic data set, this valuable study seeks to show that potentially advantageous alleles are on average older than neutral alleles, invoking the action of balancing selection as the underlying explanation. Currently it is unfortunately unclear how robust the estimates of allele ages are, and the evidence for the authors' proposal is therefore at this stage incomplete. If confirmed, the conclusions would be of interest to population genomicists, especially those studying humans.

    Reviewed by eLife