Latest preprint reviews

  1. The recombination landscape of introgression in yeast

    This article has 3 authors:
    1. Enrique J. Schwarzkopf
    2. Nathan Brandt
    3. Caiti Smukowski Heil
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      This study aims to analyse the effect of polymorphism on meiotic recombination in subspecies of Saccharomyces. The detection of reciprocal and non-reciprocal events is based on sequencing the haploid products of meiosis, and frequencies are compared between strains having introgressed genomic segments and strains lacking such segments. Unfortunately, the method used are inadequate for quantifying the non-reciprocal events.

    Reviewed by eLife

    This article has 9 evaluationsAppears in 1 listLatest version Latest activity
  2. Machine Learning Based Modelling of Human and Insect Olfaction Screens Millions of compounds to Identify Pleasant Smelling Insect Repellents

    This article has 5 authors:
    1. Joel Kowalewski
    2. Sean M Boyle
    3. Ryan Arvidson
    4. Jadrian Ejercito
    5. Anandasankar Ray
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      This useful study uses a chemoinformatics pipeline to identify a list of candidate mosquito repellants that may be pleasant to smell and safe for humans. The strength of evidence and in particular the computational methodology are incomplete because it is insufficiently benchmarked against other leading models. At the high concentrations tested, there may also be off-target effects of the repellents on the mosquitoes that are not considered.

    Reviewed by eLife

    This article has 9 evaluationsAppears in 1 listLatest version Latest activity
  3. Learned response dynamics reflect stimulus timing and encode temporal expectation violations in superficial layers of mouse V1

    This article has 3 authors:
    1. Scott G Knudstrup
    2. Catalina Martinez
    3. Jeffrey P Gavornik
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      This paper presents useful results that extend our understanding of how the visual cortex encodes temporal structure, providing new information about sequence representations in the upper layers of the visual cortex. The evidence for prediction errors is solid, however, support for other claims regarding sparsification and simplification of activity following training is incomplete. The main concerns pertain to the confounds associated with restricted ordering within blocks that does not allow for separate plasticity mechanisms operating on different time scales.

    Reviewed by eLife

    This article has 9 evaluationsAppears in 1 listLatest version Latest activity
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