eLife

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1. Tead1 reciprocally regulates adult β-cell proliferation and function to maintain glucose homeostasis

   This article has 20 authors:

   1. Jeongkyung Lee
   2. Ruya Liu
   3. Byung S. Kim
   4. Yiqun Zhang
   5. Feng Li
   6. Rajaganapti Jagannathan
   7. Ping Yang
   8. Vinny Negi
   9. Joseph Danvers
   10. Eliana Melissa Perez-Garcia
   11. Pradip K. Saha
   12. Omaima Sabek
   13. Chad J. Creighton
   14. Cristian Coarfa
   15. Mark O. Huising
   16. Hung-Ping Shih
   17. Rita Bottino
   18. Ke Ma
   19. Mousumi Moulik
   20. Vijay K. Yechoor

   This article has been curated by 1 group:

   • Curated by eLife

     eLife assessment

     The Hippo signaling pathway plays a crucial role in controlling organ size, cell proliferation, and apoptosis, though its role in endocrine pancreas development has remained unclear. In this useful work, the authors study the function of the Tead1 transcription factor, a Hippo effector, specifically in pancreatic beta cells. They provide solid evidence, using multiple different conditional knockout models to reveal Tead1's regulatory functions in insulin secretion and beta cell proliferation. However, deeper exploration of their data and incorporating findings from existing literature on this topic would provide a clearer understanding of Tead1's role in β-cell function, within or beyond the Hippo pathway.

   Reviewed by eLife

2. We couldn't get details of this article at this time:
   10.21203/rs.3.rs-3155248/v2

3. We couldn't get details of this article at this time:
   10.1101/2024.01.15.575700

4. We couldn't get details of this article at this time:
   10.1101/2024.01.09.574925

5. We couldn't get details of this article at this time:
   10.1101/2024.01.02.573930

6. We couldn't get details of this article at this time:
   10.1101/2024.01.02.573853

7. We couldn't get details of this article at this time:
   10.1101/2023.06.07.543976

8. We couldn't get details of this article at this time:
   10.1101/2021.11.17.465477

9. We couldn't get details of this article at this time:
   10.1101/2021.10.04.462977

10. We couldn't get details of this article at this time:
    10.1101/2023.10.24.563805