Latest preprint reviews

  1. Explaining the counter-intuitive effectiveness of trophectoderm biopsy for PGT-A using computational modelling

    This article has 5 authors:
    1. Benjamin M Skinner
    2. Manuel Viotti
    3. International Registry of Mosaic Embryo Transfers (IRMET)
    4. Darren K Griffin
    5. Peter JI Ellis
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      This study presents a valuable computational model for elaborating on the interpretation of chromosomal mosaicism in preimplantation embryos. The evidence supporting the claims of the authors is incomplete due to the assumption that is possible to quantify the cells in the embryo, oversimplification of mitotic errors, and the inclusion of the self-correction premise. The work will be of interest to embryologists, and geneticists working on reproductive medicine.

    Reviewed by eLife

    This article has 5 evaluationsAppears in 1 listLatest version Latest activity
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