Latest preprint reviews

  1. Neuropilin-1 controls vascular permeability through juxtacrine regulation of endothelial adherens junctions

    This article has 5 authors:
    1. Sagnik Pal
    2. Yangyang Su
    3. Emmanuel Nwadozi
    4. Lena Claesson-Welsh
    5. Mark Richards
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      This study is focused on the question of how Nrp1 contributes to the regulation of vascular permeability and whether or why there are differences between different vascular beds. The scientific concept of this paper suggests a possible role of Nrp1 on perivascular cells as a participant in the regulation of vascular permeability. This concept is interesting and potentially useful. However, the methodology and quantitative analysis are currently inadequate to fully support the claims.

    Reviewed by eLife

    This article has 4 evaluationsAppears in 1 listLatest version Latest activity
  2. The French flag problem revisited: Creating robust and tunable axial patterns without global signaling

    This article has 3 authors:
    1. Stephan Kremser
    2. Gabriel Vercelli
    3. Ulrich Gerland
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      This important study uses cellular automata and evolution algorithms to offer an alternative to long-range signalling models of developmental patterning. The computational evidence that local rules suffice to produce a robust and global pattern is convincing. With some additional insights that connect the theoretical findings back to real biological examples, this work could be of interest to the broad community of developmental and systems biologists.

    Reviewed by eLife

    This article has 3 evaluationsAppears in 1 listLatest version Latest activity
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