eLife

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   10.1101/2024.05.21.595248

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   10.1101/2024.05.20.595003

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   10.1101/2024.05.15.594343

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   10.1101/2024.05.06.592666

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   10.1101/2024.04.11.589009

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   10.1101/2024.05.02.592210

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   10.1101/2024.04.03.587975

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   10.1101/2024.01.15.575740

9. Androgen deprivation triggers a cytokine signaling switch to induce immune suppression and prostate cancer recurrence

   This article has 8 authors:

   1. Kai Sha
   2. Renyuan Zhang
   3. Aerken Maolake
   4. Shalini Singh
   5. Gurkamal Chatta
   6. Kevin H Eng
   7. Kent L Nastiuk
   8. John J Krolewski

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This potentially valuable work aimed at a better understanding of the mechanisms of response and resistance to androgen deprivation therapy in prostate cancer using genetically engineered mouse models. A key observation relates to the timing of TNF blockage therapy and the concept of a "TNF switch." The solid data were collected using conventional approaches and the conclusions are mostly justified, particularly with the inclusion of more detailed statistics in the revision. The work will be of interest to the prostate cancer research community.

   Reviewed by eLife

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    10.1101/2020.06.25.172635