Latest preprint reviews

  1. Single-cell and spatial transcriptomic analyses reveal the dynamic transcript profiles of myocardial lymphangiogenesis post-myocardial infarction

    This article has 12 authors:
    1. Jiaqi He
    2. Dali Zhang
    3. Haixu Song
    4. Ziqi Liu
    5. Dan Liu
    6. Xiaolin Zhang
    7. Xiaojie Zhao
    8. Yan Zhang
    9. Jing Liu
    10. Jiaxin Xu
    11. Chenghui Yan
    12. Yaling Han
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      This study presents useful albeit preliminary findings on transcriptome changes in cardiac lymphatic cells after myocardial infarction in mice. Despite revision, the conclusions of the authors remain uncertain as sample sizes in general are very low, and even sometimes too low to allow for valid statistical comparisons. Accordingly, there are concerns regarding statistical robustness, raised by both the editors and the reviewers. While the single-cell transcriptomic data were analyzed using solid advanced methodology, too few cells were included in the scRNA-seq data set and the spatial transcriptomics analyses. Thus, this study rather represents more a collection of preliminary transcriptomic data than a full scientific report that would definitively advance the field.

    Reviewed by eLife

    This article has 13 evaluationsAppears in 1 listLatest version Latest activity
  2. Salmonids elicit an acute behavioral response to heterothermal environments

    This article has 7 authors:
    1. Robert Naudascher
    2. Stefano Brizzolara
    3. Jonasz Slomka
    4. Robert M Boes
    5. Markus Holzner
    6. Luiz GM Silva
    7. Roman Stocker
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      This valuable paper investigates how fish avoid thermal disturbances that occur on fast timescales. The authors use a creative experimental approach that quickly creates a vertical thermal interface, which they combine with careful behavioral analyses. The evidence supporting their results is solid, but there is a potential confounding factor between temperature and vertical positioning, and characterization of the thermal interface would greatly assist in interpreting the results.

    Reviewed by eLife

    This article has 8 evaluationsAppears in 1 listLatest version Latest activity
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