eLife

Latest preprint reviews

1. STAG3 promotes exit from pluripotency through post-transcriptional mRNA regulation in the cytoplasm

   This article has 10 authors:

   1. Sam Weeks
   2. Dubravka Pezic
   3. Martin Dodel
   4. Kunal Shah
   5. Amandeep Bhamra
   6. Stephen Henderson
   7. Silvia Surinova
   8. Tyson Sharp
   9. Faraz Mardakheh
   10. Suzana Hadjur

   This article has been curated by 1 group:

   • Curated by eLife

     eLife assessment

     This potentially valuable study reports new and unexpected roles of STAG3 in regulating exit from pluripotency in mouse embryonic stem cells (mESCs). However, the evidence for the proposed role of STAG3 in the post-transcriptional regulation of gene expression is viewed as yet incomplete. The work will be of interest to colleagues studying stem cells, early steps in differentiation, and gene regulation.

   Reviewed by eLife

2. We couldn't get details of this article at this time:
   10.1101/2024.05.04.592262

3. Sox9 marks limbal stem cells and is required for asymmetric cell fate switch in the corneal epithelium

   This article has 10 authors:

   1. Gabriella Rice
   2. Olivia Farrelly
   3. Sixia Huang
   4. Paola Kuri
   5. Ezra Curtis
   6. Lisa Ohman
   7. Ning Li
   8. Christopher Lengner
   9. Vivian Lee
   10. Panteleimon Rompolas

   This article has been curated by 1 group:

   • Curated by eLife

     eLife assessment

     This fundamental work advances our understanding of the regulation of corneal stem cell fate and differentiation, identifying Sox9 as a player in this process. The evidence supporting the conclusions is compelling, with rigorous genomic experiments and genetic mouse models that are state-of-the-art in the field. The work will be of broad interest to developmental, stem cell, and transcriptional biologists.

   Reviewed by eLife

4. Ripply1 and Gsc collectively suppress anterior endoderm differentiation from prechordal plate progenitors

   This article has 18 authors:

   1. Tao Cheng
   2. Xiang Liu
   3. Yang Dong
   4. Yi-Meng Tian
   5. Yan-Yi Xing
   6. Chen-Yi Chen
   7. Cong Liu
   8. Yun-Fei Li
   9. Ying Huang
   10. Ding-Hao Zhuo
   11. Xiao Xu
   12. Jing-Yun Luan
   13. Xin-Xin Fu
   14. Zi-Xin Jin
   15. Jing Mo
   16. Xiang Xu
   17. Hong-Qing Liang
   18. Peng-Fei Xu

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This study provides a useful analysis of the changes in chromatin organization and gene expression that occur during the differentiation of two cell types (anterior endoderm and prechordal plate) from a common progenitor in zebrafish, together with investigations into the molecular factors involved. Although the findings are consistent with previous work, the evidence presented appears to be incomplete and would benefit from more rigorous quantification of live imaging and Cre-Lox experiments, a stronger rationale and controls for experiments manipulating chromatin remodeling factors, and a strong justification for the explant model especially given differences between explant and whole embryo data. This work may be of interest to zebrafish developmental biologists investigating the mechanisms underlying specification.

   Reviewed by eLife, Review Commons

5. We couldn't get details of this article at this time:
   10.1101/2024.06.20.599315

6. We couldn't get details of this article at this time:
   10.1101/2024.07.11.603062

7. We couldn't get details of this article at this time:
   10.1101/2024.05.20.594480

8. We couldn't get details of this article at this time:
   10.1101/2024.04.05.588308

9. We couldn't get details of this article at this time:
   10.1101/2024.07.05.602232

10. Should I stay or should I go? Spatiotemporal dynamics of bacterial biofilms in confined flows

    This article has 6 authors:

    1. Massinissa Benbelkacem
    2. Gabriel Ramos
    3. Fatima El Garah
    4. Yara Abidine
    5. Christine Roques
    6. Yohan Davit

    This article has been curated by 1 group:

    • Curated by eLife

      eLife Assessment

      This important study combines microfluidic experiments with mathematical modeling to elucidate the reciprocal interplay between flow dynamics and biofilm growth and detachment. Using Pseudomonas aeruginosa as a model organism, the authors identify several key regimes and stages of biofilm development. Overall, the comparison between experimental observations of biofilm behavior under varying flow conditions and corresponding theoretical predictions forms a compelling understanding of the processes involved in biofilm dynamics. The results will be of interest to researchers studying biofilms and their technological and biological applications.

    Reviewed by eLife