eLife

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1. We couldn't get details of this article at this time:
   10.1101/2023.09.14.557555

2. We couldn't get details of this article at this time:
   10.1101/2021.10.05.463267

3. We couldn't get details of this article at this time:
   10.1101/2024.05.17.594656

4. We couldn't get details of this article at this time:
   10.1101/2024.07.12.603262

5. Hypersensitivity of the vimentin cytoskeleton to net-charge states and Coulomb repulsion

   This article has 5 authors:

   1. Bret A Unger
   2. Chun Ying Wu
   3. Alexander A Choi
   4. Changdong He
   5. Ke Xu

   This article has been curated by 1 group:

   • Curated by eLife

     eLife assessment

     This valuable study provides new insight into the disassembly of vimentin filaments and the dependence of this mechanism on net charge, albeit with incomplete evidence. In particular, the experimental replicates are limited (in most cases n=1), there is a lack of quantitative analysis to substantiate claims, inconsistency of the proposed mechanisms with previously published work, and lack of biochemical evidence supporting the observations in cells. Addressing these concerns would strengthen the manuscript and help support the proposed hypothesis on vimentin disassembly.

   Reviewed by eLife

6. We couldn't get details of this article at this time:
   10.1101/2024.04.24.590865

7. We couldn't get details of this article at this time:
   10.1101/2023.08.31.555760

8. We couldn't get details of this article at this time:
   10.1101/2024.07.09.598733

9. We couldn't get details of this article at this time:
   10.1101/2024.06.26.600804

10. Ocular biomarker profiling after complement factor I gene therapy in geographic atrophy secondary to age-related macular degeneration

    This article has 24 authors:

    1. Thomas M Hallam
    2. Emanuela Gardenal
    3. Fraser McBlane
    4. GaEun Cho
    5. Lucy Lee Ferraro
    6. Eva Pekle
    7. Darlene Lu
    8. Kate Carney
    9. Claire Wenden
    10. Hannah Beadsmoore
    11. Sergio Kaiser
    12. Lauren Drage
    13. Thomas Haye
    14. Iris Kassem
    15. Nalini Rangaswamy
    16. Ma’en Obeidat
    17. Cyndy Grosskreutz
    18. Magali Saint-Geniez
    19. David H Steel
    20. Robert E MacLaren
    21. Scott Ellis
    22. Claire L Harris
    23. Stephen Poor
    24. Amy V Jones

    This article has been curated by 1 group:

    • Curated by eLife

      eLife Assessment

      This important work advances our understanding of factors influencing efficacy assessments and biomarker viability for complement-directed gene therapy against age-related macular degeneration. The data presented is convincing and offers insights and teachings for the design of gene therapy and complement-targeted therapeutics in the eye and more broadly for future ocular biomarker studies.

    Reviewed by eLife