Latest preprint reviews

  1. Distinct gradients of cortical architecture capture visual representations and behavior across the lifespan

    This article has 7 authors:
    1. Xiayu Chen
    2. Xingyu Liu
    3. Patricia Maria Hoyos
    4. Edan Daniel Hertz
    5. Jewelia K Yao
    6. Zonglei Zhen
    7. Jesse Gomez
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      This valuable study draws on large-scale multimodal MRI measurements of human brain structure across the lifespan to offer a new perspective on visual cortex architecture. The data provide compelling evidence for two cortical architectural gradients that show distinct functional, cytoarchitectural, behavioural, and lifespan profiles. One gradient captures a broad early-to-higher-level visual cortical hierarchy in which cortical thickness tissue density covary; the other reflects more localised divergence from this relationship, notably predicting putative anterior temporal visual field representations that have not previously been described.

    Reviewed by eLife

    This article has 6 evaluationsAppears in 1 listLatest version Latest activity
  2. Prolonged Pain Reliably Slows Peak Alpha Frequency by Reducing Fast Alpha Power

    This article has 7 authors:
    1. Andrew J Furman
    2. Mariya Prokhorenko
    3. Michael L Keaser
    4. Jing Zhang
    5. Shuo Chen
    6. Ali Mazaheri
    7. David A Seminowicz
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      This study presents valuable findings on changes in neuronal alpha activity elicited by prolonged pain in healthy human participants. The evidence supporting the claims of the authors, however, is incomplete and would benefit from clarifications of analytical strategies, additional statistical analyses, and shaping of the interpretations. With the methodological and interpretative parts strengthened, the work will be of interest to neuroscientists investigating the brain mechanisms of pain to identify new approaches to pain treatment

    Reviewed by eLife

    This article has 4 evaluationsAppears in 1 listLatest version Latest activity
  3. An integrin centered complex coordinates ion transport and pH to regulate f-actin organization and cell migration in breast cancer

    This article has 12 authors:
    1. Chiara Capitani
    2. Jessica Iorio
    3. Elena Lastraioli
    4. Claudia Duranti
    5. Giacomo Bagni
    6. Ginevra Chioccioli Altadonna
    7. Rossella Colasurdo
    8. Giorgia Scarpellino
    9. Scott P. Fraser
    10. Andrea Becchetti
    11. Mustafa B. A. Djamgoz
    12. Annarosa Arcangeli
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      This study presents a valuable finding on the identification of a complex consisting of NHE1, hERG1, β1/integrin and NaV1.5 on the membrane of breast cancer cells. The evidence supporting the claims of the authors is somewhat incomplete. The inclusion of clarification of some experimental design and the amendment of cropping Western blot data would have strengthened the study. The work will be of interest to scientists working on breast cancer.

    Reviewed by eLife

    This article has 3 evaluationsAppears in 1 listLatest version Latest activity
  4. Dapagliflozin improves endothelial integrity and hemodynamics in endotoxin treated mice through an apolipoprotein M dependent pathway

    This article has 18 authors:
    1. Carla Valenzuela Ripoll
    2. Zhen Guo
    3. Tripti Kumari
    4. Kana N. Miyata
    5. Mualla Ozcan
    6. Ahmed Diab
    7. Amanda Girardi
    8. Li He
    9. Attila Kovacs
    10. Carla Weinheimer
    11. Jess Nigro
    12. Jan Oscarsson
    13. Russell Esterline
    14. Joel Schilling
    15. Mikhail Kosiborod
    16. Christina Christoffersen
    17. Jaehyung Cho
    18. Ali Javaheri
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      SGLT2 inhibitors (SGLT2i) have assumed important roles in reducing cardiovascular risk, particularly in those with diabetes. It has become appreciated that its protective effects are likely beyond their ability to lower blood sugar levels. This research presents a novel approach to studying the SGLT2i mechanism of action which is yet to be fully elucidated.

    Reviewed by eLife

    This article has 5 evaluationsAppears in 1 listLatest version Latest activity
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