eLife

Latest preprint reviews

1. We couldn't get details of this article at this time:
   10.1101/2022.04.19.488727

2. We couldn't get details of this article at this time:
   10.1101/2024.12.30.630733

3. We couldn't get details of this article at this time:
   10.1101/2024.01.11.575207

4. The title and authors for this article are not available from our external data provider yet:
   10.48550/arxiv.2307.05304v3

5. We couldn't get details of this article at this time:
   10.21203/rs.3.rs-3026480/v2

6. The resource elasticity of control

   This article has 3 authors:

   1. Levi Solomyak
   2. Aviv Emanuel
   3. Eran Eldar

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This study makes the valuable claim that people track, specifically, the elasticity of control (that is, the degree to which outcome depends on how many resources - such as money - are invested), and that control elasticity is impaired in certain types of psychopathologies. A novel task is introduced that provides solid evidence that this learning process occurs and that human behavior is sensitive to changes in the elasticity of control. Evidence that elasticity inference is distinct from more general learning mechanisms and is related to psychopathology remains incomplete.

   Reviewed by eLife

7. We couldn't get details of this article at this time:
   10.1101/2023.11.21.23298816

8. We couldn't get details of this article at this time:
   10.1101/2025.01.18.633745

9. Notch signaling maintains a progenitor-like subclass of hepatocellular carcinoma

   This article has 20 authors:

   1. Kerstin Seidel
   2. Robert Piskol
   3. Thi Thu Thao Nguyen
   4. Amy Shelton
   5. Charisa Cottonham
   6. Cecile C de la Cruz
   7. Joseph Castillo
   8. Jesse Garcia
   9. Udi Segal
   10. Mark Merchant
   11. Yeqing Angela Yang
   12. Jasmine Chen
   13. Musa Ahmed
   14. Alexis Scherl
   15. Rajesh Vij
   16. Lluc Mosteiro
   17. Yan Wu
   18. Zora Modrusan
   19. Ciara Metcalfe
   20. Chris Siebel

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     In this valuable study, Seidel et al. identify and characterize a novel subset of hepatocellular carcinoma patient-derived xenograft models defined by active Jagged 1-Notch2 signaling and a distinctive progenitor-like gene expression profile. Within the limitations of the PDX system they used, their methods are state-of-the-art, their data are strong and believable, and their conclusions are convincing. However, the ability to identify HCC patients that might respond is limited, and the mechanistic assessment downstream of JAG1/NOTCH2 is relatively descriptive. Some additional clarifications and experiments would strengthen the paper.

   Reviewed by eLife

10. Mitochondrial adenine base editing of mouse somatic tissues via adeno-associated viral delivery

    This article has 6 authors:

    1. Christian D Mutti
    2. Lindsey Van Haute
    3. Lucia Luengo-Gutierrez
    4. Keira Turner
    5. Pedro Silva-Pinheiro
    6. Michal Minczuk

    This article has been curated by 1 group:

    • Curated by eLife

      eLife Assessment

      The authors have demonstrated the use of adenine base editors delivered via adeno-associated viruses to introduce edits in the mitochondrial genome. The manuscript describes the methodology well, and the conclusions are convincingly supported by the results. The valuable results highlight the potential of these base editors to model mtDNA variations in somatic tissues in animal models.

    Reviewed by eLife