eLife

Latest preprint reviews

1. We couldn't get details of this article at this time:
   10.1101/2024.09.27.615483

2. Trial-level Representational Similarity Analysis

   This article has 7 authors:

   1. Shenyang Huang
   2. Cortney M Howard
   3. Paul C Bogdan
   4. Ricardo Morales-Torres
   5. Matthew Slayton
   6. Roberto Cabeza
   7. Simon W Davis

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This study proposes a potentially useful improvement on a popular fMRI method for quantifying representational similarity in brain measurements by focusing on representational strength at the single trial level and adding linear mixed effects modeling for group-level inference. The manuscript provides solid evidence of increased sensitivity with no loss of precision compared to more classic versions of the method. However, several assumptions are insufficiently motivated, and it is unclear to what extent the approach would generalize to other paradigms.

   Reviewed by eLife

3. We couldn't get details of this article at this time:
   10.1101/2025.03.12.642838

4. We couldn't get details of this article at this time:
   10.1101/2024.12.20.629829

5. We couldn't get details of this article at this time:
   10.1101/2024.11.14.623618

6. Distal Gene Expression Governed by Lamins and Nesprins via Chromatin Conformation Change

   This article has 4 authors:

   1. Haihui Zhang
   2. Zhengyang Lei
   3. Fatemeh Momen-Heravi
   4. Peiwu Qin

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This study provides valuable information on the impact of Lamin A/C knockdown on gene expression using RNA-Seq analysis, as well as on telomere dynamics through live cell imaging. However, the conclusions remain inadequately supported by the current data, and several of the major technical concerns raised in the first round have not yet been fully resolved.

   Reviewed by eLife

7. We couldn't get details of this article at this time:
   10.1101/2025.02.28.640832

8. The influence of heavy metal stress on the evolutionary transition of teosinte to maize

   This article has 3 authors:

   1. Jonathan Acosta-Bayona
   2. Miguel Vallebueno-Estrada
   3. Jean-Philippe Vielle-Calzada

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This study investigates whether heavy metal stress can induce maize-like phenotypic and molecular responses in teosinte and whether these responses overlap with genomic regions implicated in domestication. By combining copper and cadmium treatments with quantitative phenotyping, gene-expression analyses, and expanded assessments of nucleotide diversity across a key chromosome 5 interval, the authors provide an integrated view of how abiotic stress responses intersect with domestication-related traits. The significance of the findings is valuable, as the work offers meaningful insights for the subfield of maize evolution and stress biology by extending heavy-metal response analyses to teosinte and linking them to domestication-associated loci, although the evolutionary implications remain indirect. The strength of evidence is solid, with appropriately designed and quantitatively supported experiments that broadly support the claims, but do not yet establish a causal or historical role for heavy metal stress in domestication.

   Reviewed by eLife

9. We couldn't get details of this article at this time:
   10.1101/2025.04.13.648654

10. Calibration and validation strategy for electromechanical cardiac digital twins

    This article has 7 authors:

    1. Zhinuo Jenny Wang
    2. Maxx Holmes
    3. Ruben Doste
    4. Julia Camps
    5. Francesca Margara
    6. Mariano Vazquez
    7. Blanca Rodriguez

    This article has been curated by 1 group:

    • Curated by eLife

      eLife Assessment

      This study offers an important set of literature-based parameter ranges for calibrating cardiac electromechanical models. The key scientific claims are largely supported by convincing evidence and carefully-documented methodologies, but a few specific issues remain only partially supported, in particular relating to the locking-free formulation, reporting of adequate details regarding the electrophysiological model (Eikonal approach), and the fact that physiological accuracy is predominantly achieved in a single chamber (the LV).

    Reviewed by eLife