eLife

Latest preprint reviews

1. We couldn't get details of this article at this time:
   10.1101/2025.03.10.641934

2. We couldn't get details of this article at this time:
   10.1101/2020.10.26.354704

3. Inducible, virus-free direct lineage reprogramming enhances scalable generation of human inner ear hair cell-like cells

   This article has 11 authors:

   1. Robert N Rainey
   2. Sam D Houman
   3. Louise Menendez
   4. Ryan Chang
   5. Litao Tao
   6. Helena Bugacov
   7. Andrew P McMahon
   8. Radha Kalluri
   9. John S Oghalai
   10. Andrew K Groves
   11. Neil Segil

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     The findings of this important study substantially advance our understanding of the transcription factors that can induce hair cell-like cells from human pluripotent stem cells. The presented evidence supporting these findings is compelling, including rigorous characterization of the effects of hair cell induction using both single-cell RNA sequencing and electrophysiological assessments.

   Reviewed by eLife

4. We couldn't get details of this article at this time:
   10.1101/2024.11.01.621152

5. Passive muscle forces in Drosophila are large but insufficient to support a fly’s weight

   This article has 7 authors:

   1. Ninghan Wang
   2. Helene Babski
   3. Jonathan Elliot Perdomo
   4. Sarah Beth McMahan
   5. Arun Ramakrishnan
   6. Tirthabir Biswas
   7. Vikas Bhandawat

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This valuable study introduces a novel experimental and modeling framework to quantify passive joint torques in Drosophila, revealing that passive forces are insufficient to support body weight, contrary to prior assumptions based on larger insects. The approach is technically impressive, combining genetic silencing, kinematic tracking, and biomechanical modeling. However, the strength of evidence is incomplete, limited by concerns about the specificity of the genetic tools, simplifications in the mechanical model, and limited functional interpretation.

   Reviewed by eLife

6. We couldn't get details of this article at this time:
   10.1101/2025.02.26.640367

7. We couldn't get details of this article at this time:
   10.1101/2024.08.13.607832

8. We couldn't get details of this article at this time:
   10.1101/2025.05.16.654513

9. We couldn't get details of this article at this time:
   10.1101/2025.05.22.655589

10. Multiple pathways prevent bi-parental mitochondria transmission in C. elegans

    This article has 5 authors:

    1. Valentine Melin
    2. Justine Cailloce
    3. Fanny Husson
    4. Jorge Merlet
    5. Vincent Galy

    This article has been curated by 1 group:

    • Curated by eLife

      eLife Assessment

      This valuable work used molecular biology, cell biology, and genetic approaches to unravel individual genes and potential pathways that contribute to paternal mitochondrial inheritance using C. elegans as the model organism. Their microscopy method is cutting edge, with sufficient biological replicates, proper control, and appropriate statistics. These findings are convincing and are of general interest for understanding mitochondrial inheritance in C. elegans, which could have implications for understanding similar biological processes in other organisms.

    Reviewed by eLife