eLife

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1. We couldn't get details of this article at this time:
   10.1101/2025.01.14.632903

2. G1 and G2 ApolipoproteinL1 modulate macrophage inflammation and lipid accumulation through the polyamine pathway

   This article has 12 authors:

   1. Esther Liu
   2. Matthew Wright
   3. Andrew O Kearney
   4. Tiffany Caza
   5. Johnson Y Yang
   6. Valerie Garcia
   7. Amal O Dadi
   8. Shuta Ishibe
   9. Navdeep S Chandel
   10. Hanrui Zhang
   11. Edward B Thorp
   12. Jennie Lin

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     The authors study how apolipoprotein L1 variants impact inflammation and lipid accumulation in macrophages. The findings will be useful for researchers investigating macrophage metabolism and inflammation. The discovery that the polyamine spermidine in part mediates such effects is interesting, but the supporting evidence for a physiologically relevant role is currently incomplete due to the lack of relevant in vivo studies.

   Reviewed by eLife

3. We couldn't get details of this article at this time:
   10.1101/2024.10.27.620542

4. SoxB1 family members inhibit Wnt signaling to promote maturation and deposition of stable neuromasts by the zebrafish Posterior Lateral Line primordium

   This article has 7 authors:

   1. Greg Palardy
   2. Kyeong-won Yoo
   3. Sana Fatma
   4. Abhishek Mukherjee
   5. Chongmin Wang
   6. Priyanka Ravi
   7. Ajay B Chitnis

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This important study explores the regulation of collective cell migration and tissue patterning in the zebrafish posterior lateral line primordium by SoxB1 transcription factors. The authors provide evidence that SoxB1 genes interact with Wnt and Fgf signaling pathways to control neuromast deposition and spacing, a process central to sensory organ development. The work offers mechanistic insight into the self-organization of migrating tissues and adds to the understanding of how transcriptional networks integrate with signaling pathways during morphogenesis. However, the strength of the evidence supporting several key conclusions is incomplete due to insufficient validation of mutant and knockdown tools, lack of quantitative analysis, and unclear experimental design details; additional quantification and more rigorous verification of gene knockdown or loss-of-function tools are needed to support the proposed model.

   Reviewed by eLife

5. We couldn't get details of this article at this time:
   10.1101/2025.05.25.655978

6. We couldn't get details of this article at this time:
   10.1101/2025.05.08.652664

7. We couldn't get details of this article at this time:
   10.1101/2025.04.04.646800

8. Convergent Cellular Adaptation to Freeze-Thaw Stress via a Quiescence-like State in Yeast

   This article has 9 authors:

   1. Charuhansini Tvishamayi
   2. Farhan Ali
   3. Nandita Chaturvedi
   4. Nithila Madhu-Kumar
   5. Zeenat Rashida
   6. Chandan Muni Reddy
   7. Ankita Ray
   8. Stephan Herminghaus
   9. Shashi Thutupalli

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This study provides valuable insight into stress biology by showing that yeast populations can rapidly evolve a trehalose producing resting state that substantially improves survival and rapid regrowth after freeze-thaw. This finding is consistent with the role of trehalose metabolism as a biophysical adaptation that is broadly relevant to the community working on environmental resilience and dormancy. The evidence is convincing: the authors integrate experimental evolution, cell-level biophysical measurements, and modelling in a mutually reinforcing manner.

   Reviewed by eLife

9. We couldn't get details of this article at this time:
   10.1101/2024.04.29.591782

10. Striatal Crosstalk Between Dopamine and Serotonin Systems

    This article has 3 authors:

    1. Yu Liu
    2. Juan Enriquez Traba
    3. Christian Lüscher

    This article has been curated by 1 group:

    • Curated by eLife

      eLife Assessment

      This useful study employs optogenetics, genetically-encoded dopamine and serotonin sensors, and patch-clamp electrophysiology to investigate modulations of neurotransmitter release between striatal dopamine and serotonin neurons - a topic of interest to neuroscientists studying the basal ganglia. The results suggest that the dopamine and serotonin systems operate largely in parallel, with the activation of serotonin neurons resulting in a small, transient dopamine release. The authors suggest that this interaction occurs via glutamate release in the ventral tegmental area, findings that are closely related to previous work. Some conclusions are incomplete requiring larger samples-sizes and controls.

    Reviewed by eLife