1. SARS-CoV-2 Spike protein activates TMEM16F-mediated platelet pro-coagulant activity

    This article has 13 authors:
    1. Ambra Cappelletto
    2. Harriet E. Allan
    3. Marilena Crescente
    4. Edoardo Schneider
    5. Rossana Bussani
    6. Hashim Ali
    7. Ilaria Secco
    8. Simone Vodret
    9. Roberto Simeone
    10. Luca Mascaretti
    11. Serena Zacchigna
    12. Timothy D. Warner
    13. Mauro Giacca

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  2. Evaluation of SARS-CoV-2 antibody point of care devices in the laboratory and clinical setting

    This article has 14 authors:
    1. Kirsty McCance
    2. Helen Wise
    3. Jennifer Simpson
    4. Becky Batchelor
    5. Harriet Hale
    6. Lindsay McDonald
    7. Azul Zorzoli
    8. Elizabeth Furrie
    9. Charu Chopra
    10. Frauke Muecksch
    11. Theodora Hatziioannou
    12. Paul D. Bieniasz
    13. Kate Templeton
    14. Sara Jenks

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  3. Using patient biomarker time series to determine mortality risk in hospitalised COVID-19 patients: A comparative analysis across two New York hospitals

    This article has 5 authors:
    1. Ben Lambert
    2. Isaac J. Stopard
    3. Amir Momeni-Boroujeni
    4. Rachelle Mendoza
    5. Alejandro Zuretti

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  4. Extent, impact, and mitigation of batch effects in tumor biomarker studies using tissue microarrays

    This article has 13 authors:
    1. Konrad H Stopsack
    2. Svitlana Tyekucheva
    3. Molin Wang
    4. Travis A Gerke
    5. J Bailey Vaselkiv
    6. Kathryn L Penney
    7. Philip W Kantoff
    8. Stephen P Finn
    9. Michelangelo Fiorentino
    10. Massimo Loda
    11. Tamara L Lotan
    12. Giovanni Parmigiani
    13. Lorelei A Mucci
    This article has been curated by 1 group:
    • Curated by eLife

      Evaluation Summary:

      Tissue microarrays (TMA) have become a mainstay in clinical and basic research, for both discovery and validation of biomarkers. This manuscript provides relevant methodologic considerations for cancer researchers investigating tissue-biomarkers using TMAs. A comprehensive investigation was conducted using a combination of analytic approaches using empirical data and simulated data to support key findings and conclusions. The authors approach the possible sampling variation in a thoughtful way, not only quantifying the issue systematically, but working towards a solution.

      (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. The reviewers remained anonymous to the authors.)

    Reviewed by eLife

    This article has 4 evaluationsAppears in 1 listLatest version Latest activity
  5. SARS-CoV-2 wildlife surveillance in Ontario and Québec

    This article has 21 authors:
    1. JE Greenhorn
    2. JD Kotwa
    3. J Bowman
    4. L Bruce
    5. T Buchanan
    6. PA Buck
    7. CM Davy
    8. A Dibernardo
    9. L Flockhart
    10. M Gagnier
    11. A Hou
    12. CM Jardine
    13. S Lair
    14. LR Lindsay
    15. A Massé
    16. PK Muchaal
    17. LA Nituch
    18. A Sotto
    19. B Stevens
    20. L Yip
    21. S Mubareka

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  6. Acute SARS-CoV-2 infection in pregnancy is associated with placental ACE-2 shedding

    This article has 10 authors:
    1. Elizabeth S. Taglauer
    2. Elisha M. Wachman
    3. Lillian Juttukonda
    4. Timothy Klouda
    5. Jiwon Kim
    6. Qiong Wang
    7. Asuka Ishiyama
    8. David J. Hackam
    9. Ke Yuan
    10. Hongpeng Jia

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  7. A live attenuated virus-based intranasal COVID-19 vaccine provides rapid, prolonged, and broad protection against SARS-CoV-2

    This article has 36 authors:
    1. Junyu Chen
    2. Pui Wang
    3. Lunzhi Yuan
    4. Liang Zhang
    5. Limin Zhang
    6. Hui Zhao
    7. Congjie Chen
    8. Xijing Wang
    9. Jinle Han
    10. Yaode Chen
    11. Jizong Jia
    12. Zhen Lu
    13. Junping Hong
    14. Zicen Lu
    15. Qian Wang
    16. Rirong Chen
    17. Ruoyao Qi
    18. Jian Ma
    19. Min Zhou
    20. Huan Yu
    21. Chunlan Zhuang
    22. Xiaohui Liu
    23. Qiangyuan Han
    24. Guosong Wang
    25. Yingying Su
    26. Quan Yuan
    27. Tong Cheng
    28. Ting Wu
    29. Xiangzhong Ye
    30. Tianying Zhang
    31. Changgui Li
    32. Jun Zhang
    33. Huachen Zhu
    34. Yixin Chen
    35. Honglin Chen
    36. Ningshao Xia

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  8. Visceral Fat Inflammation and Fat Embolism are associated with Lung’s Lipidic Hyaline Membranes in COVID-19 patients

    This article has 16 authors:
    1. Georgia Colleluori
    2. Laura Graciotti
    3. Mauro Pesaresi
    4. Angelica Di Vincenzo
    5. Jessica Perugini
    6. Eleonora Di Mercurio
    7. Sara Caucci
    8. Patrizia Bagnarelli
    9. Cristina M. Zingaretti
    10. Enzo Nisoli
    11. Stefano Menzo
    12. Adriano Tagliabracci
    13. Annie Ladoux
    14. Christian Dani
    15. Antonio Giordano
    16. Saverio Cinti

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  9. Evaluation of Viral Loads in Patients With SARS-CoV-2 Delta Variant Infection: Higher Loads Do Not Translate Into Different Testing Scenarios

    This article has 5 authors:
    1. Juan Luis Gomez Marti
    2. Ashley Mays
    3. Melissa McCullough
    4. Alan Wells
    5. Tung Phan

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    This article has 1 evaluationAppears in 1 listLatest version Latest activity
  10. Single cell profiling in COVID-19 associated acute kidney injury reveals patterns of tubule injury and repair in human

    This article has 15 authors:
    1. David Legouis
    2. Anna Rinaldi
    3. Gregoire Arnoux
    4. Thomas Verissimo
    5. Jennifer Scotti-Gerber
    6. Anna Faivre
    7. Manuel Schibler
    8. Andrea Rinaldi
    9. Maarten Naesens
    10. Kari Koppitch
    11. Jerome Pugin
    12. Andrew P McMahon
    13. Solange Moll
    14. Sophie de Seigneux
    15. Pietro E Cippà

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