Pathology

The clinical impact of maternal COVID-19 on mothers, their infants, and placentas with an analysis of vertical transfer of maternal SARS-CoV-2-specific IgG antibodies

1. J.D. Ward
2. C. Cornaby
3. T. Kato
4. R.C. Gilmore
5. D. Bunch
6. M.B. Miller
7. R.C. Boucher
8. J.L. Schmitz
9. F.A. Askin
10. L.R. Scanga

Reviewed by ScreenIT

Comprehensive analysis of disease pathology in immunocompetent and immunocompromised hamster models of SARS-CoV-2 infection

1. Santhamani Ramasamy
2. Afsal Kolloli
3. Ranjeet Kumar
4. Seema Husain
5. Patricia Soteropoulos
6. Theresa L. Chang
7. Selvakumar Subbian

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Development of a One-Step Qualitative RT-PCR Assay to Detect the SARS-CoV-2 Omicron (B.1.1.529) Variant in Respiratory Specimens

1. Tung Phan
2. Stephanie Boes
3. Melissa McCullough
4. Jamie Gribschaw
5. Jane Marsh
6. Lee H. Harrison
7. Alan Wells

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Signals of Significantly Increased Vaccine Breakthrough, Decreased Hospitalization Rates, and Less Severe Disease in Patients with Coronavirus Disease 2019 Caused by the Omicron Variant of Severe Acute Respiratory Syndrome Coronavirus 2 in Houston, Texas

1. Paul A. Christensen
2. Randall J. Olsen
3. S. Wesley Long
4. Richard Snehal
5. James J. Davis
6. Matthew Ojeda Saavedra
7. Kristina Reppond
8. Madison N. Shyer
9. Jessica Cambric
10. Ryan Gadd
11. Rashi M. Thakur
12. Akanksha Batajoo
13. Regan Mangham
14. Sindy Pena
15. Trina Trinh
16. Jacob C. Kinskey
17. Guy Williams
18. Robert Olson
19. Jimmy Gollihar
20. James M. Musser

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Utilization of a SARS-CoV-2 Variant Assay for the Rapid Differentiation of Omicron and Delta

1. Nicholas Barasch
2. Jameel Iqbal
3. Marvin Coombs
4. Sofia Kazi
5. Jessica Wang-Rodriguez
6. Mark Holodniy
7. Michael Gelman

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Pre-clinical evaluation of antiviral activity of nitazoxanide against SARS-CoV-2

1. Jean-Sélim Driouich
2. Maxime Cochin
3. Franck Touret
4. Paul-Rémi Petit
5. Magali Gilles
6. Grégory Moureau
7. Karine Barthélémy
8. Caroline Laprie
9. Thanaporn Wattanakul
10. Palang Chotsiri
11. Richard M. Hoglund
12. Joel Tarning
13. Laurent Fraisse
14. Peter Sjö
15. Charles E. Mowbray
16. Fanny Escudié
17. Ivan Scandale
18. Eric Chatelain
19. Xavier de Lamballerie
20. Caroline Solas
21. Antoine Nougairède

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SARS-CoV-2 Spike protein activates TMEM16F-mediated platelet pro-coagulant activity

1. Ambra Cappelletto
2. Harriet E. Allan
3. Marilena Crescente
4. Edoardo Schneider
5. Rossana Bussani
6. Hashim Ali
7. Ilaria Secco
8. Simone Vodret
9. Roberto Simeone
10. Luca Mascaretti
11. Serena Zacchigna
12. Timothy D. Warner
13. Mauro Giacca

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Evaluation of SARS-CoV-2 antibody point of care devices in the laboratory and clinical setting

1. Kirsty McCance
2. Helen Wise
3. Jennifer Simpson
4. Becky Batchelor
5. Harriet Hale
6. Lindsay McDonald
7. Azul Zorzoli
8. Elizabeth Furrie
9. Charu Chopra
10. Frauke Muecksch
11. Theodora Hatziioannou
12. Paul D. Bieniasz
13. Kate Templeton
14. Sara Jenks

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Using patient biomarker time series to determine mortality risk in hospitalised COVID-19 patients: A comparative analysis across two New York hospitals

1. Ben Lambert
2. Isaac J. Stopard
3. Amir Momeni-Boroujeni
4. Rachelle Mendoza
5. Alejandro Zuretti

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Extent, impact, and mitigation of batch effects in tumor biomarker studies using tissue microarrays

1. Konrad H Stopsack
2. Svitlana Tyekucheva
3. Molin Wang
4. Travis A Gerke
5. J Bailey Vaselkiv
6. Kathryn L Penney
7. Philip W Kantoff
8. Stephen P Finn
9. Michelangelo Fiorentino
10. Massimo Loda
11. Tamara L Lotan
12. Giovanni Parmigiani
13. Lorelei A Mucci

• Curated by eLife

  Evaluation Summary:

  Tissue microarrays (TMA) have become a mainstay in clinical and basic research, for both discovery and validation of biomarkers. This manuscript provides relevant methodologic considerations for cancer researchers investigating tissue-biomarkers using TMAs. A comprehensive investigation was conducted using a combination of analytic approaches using empirical data and simulated data to support key findings and conclusions. The authors approach the possible sampling variation in a thoughtful way, not only quantifying the issue systematically, but working towards a solution.

  (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. The reviewers remained anonymous to the authors.)

Reviewed by eLife