1. How sleeping minds decide: state-specific reconfigurations of lexical decision-making

    This article has 8 authors:
    1. Tao Xia
    2. Chuan-Peng Hu
    3. Basak Türker
    4. Esteban Munoz Musat
    5. Lionel Naccache
    6. Isabelle Arnulf
    7. Delphine Oudiette
    8. Xiaoqing Hu

    Reviewed by preLights

    This article has 1 evaluationAppears in 1 listLatest version Latest activity
  2. Disentangling acute motor deficits and adaptive responses evoked by the loss of cerebellar output

    This article has 6 authors:
    1. Nirvik Sinha
    2. Sharon Israely
    3. Ora Ben Harosh
    4. Ran Harel
    5. Julius PA Dewald
    6. Yifat Prut
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      Using a unique cerebellar disruption approach in non-human primates, this study provides valuable new insight into how cerebellar inputs to the motor cortex contribute to reaching. The findings convincingly demonstrate that reaching movements following cerebellar disruption slow down because of both an acute deficit in producing muscle activity as well as a progressive decline in compensating for limb dynamics. This work will be of interest to neuroscientists and clinicians interested in cerebellar function and pathology.

    Reviewed by eLife

    This article has 15 evaluationsAppears in 1 listLatest version Latest activity
  3. Neural dynamics of visual working memory representation during sensory distraction

    This article has 4 authors:
    1. Jonas Karolis Degutis
    2. Simon Weber
    3. Joram Soch
    4. John-Dylan Haynes
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      This important study reports a reanalysis of one experiment of a previously-published report to characterize the dynamics of neural population codes during visual working memory in the presence of distracting information. This paper presents solid evidence that working memory representations are dynamic and distinct from sensory representations of intervening distractions. This research will be of interest to cognitive neuroscientists working on the neural bases of visual perception and memory.

    Reviewed by eLife

    This article has 10 evaluationsAppears in 1 listLatest version Latest activity
  4. Striatal cholinergic interneuron pause response requires Kv1 channels, is absent in dyskinetic mice, and is restored by dopamine D5 receptor inverse agonism

    This article has 6 authors:
    1. Cecilia Tubert
    2. Rodrigo Manuel Paz
    3. Agostina Mónica Stahl
    4. Kianny Miroslava Sanchez Armijos
    5. Lorena Rela
    6. Mario Gustavo Murer
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      The authors investigated the mechanisms underlying the pause in striatal cholinergic interneurons (SCINs) induced by thalamic input, identifying that Kv1 channels play a key role in this burst-dependent pause. The experimental evidence is convincing.
      The study provides important mechanistic insights into how burst activity in SCINs leads to a subsequent pause, highlighting the involvement of D1/D5 receptors.

    Reviewed by eLife

    This article has 15 evaluationsAppears in 1 listLatest version Latest activity
  5. Group identification drives brain integration for collective performance

    This article has 4 authors:
    1. Enhui Xie
    2. Shuyi Zha
    3. Yiyang Xu
    4. Xianchun Li
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      This timely and important study used functional near-infrared spectroscopy hyperscanning to examine the neural correlates of how group identification influences collective behavior. The work provides solid evidence to indicate that the synchronization of brain activity between different people underlies collective performance and that changes in brain activity patterns within individuals may, in turn, underlie this between-person synchrony, although the order in which different task stages were completed could not be counter-balanced. This study will be of interest to researchers investigating the neuroscience of social behaviour.

    Reviewed by eLife

    This article has 10 evaluationsAppears in 1 listLatest version Latest activity
  6. Differential roles of NaV1.2 and NaV1.6 in neocortical pyramidal cell excitability

    This article has 11 authors:
    1. Joshua D Garcia
    2. Chenyu Wang
    3. Ryan PD Alexander
    4. Emmie Banks
    5. Timothy Fenton
    6. Jean-Marc DeKeyser
    7. Tatiana V Abramova
    8. Alfred L George
    9. Roy Ben-Shalom
    10. David H Hackos
    11. Kevin J Bender
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      This manuscript presents a clever and powerful approach to examining differential roles of Nav1.2 and Nav1.6 channels in excitability of neocortical pyramidal neurons, by engineering mice in which a sulfonamide inhibitor of both channels has reduced affinity for one or the other channels. Overall, the results in the manuscript are compelling and give important information about differential roles of Nav1.6 and Nav1.2 channels. Activity-dependent inactivation of NaV1.6 was also found to attenuate seizure-like activity in cells, demonstrating the promise of activity-dependent NaV1.6-specific pharmacotherapy for epilepsy.

    Reviewed by eLife

    This article has 9 evaluationsAppears in 1 listLatest version Latest activity
  7. A neuromorphic model of active vision shows how spatiotemporal encoding in lobula neurons can aid pattern recognition in bees

    This article has 6 authors:
    1. HaDi MaBouDi
    2. Mark Roper
    3. Marie-Genevieve Guiraud
    4. Mikko Juusola
    5. Lars Chittka
    6. James A.R. Marshall
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      Inspired by bee's visual behavior, the goal of the manuscript is to develop a model of visual scanning, visual processing and learning to recognize visual patterns. In this model, pre-training with natural images leads to the formation of spatiotemporal receptive fields that can support associative learning. Due to an incomplete test of the necessity and sufficiency of the features included in the model, it cannot be concluded that the model is either the "minimal circuit" or the most biologically plausible circuit of this system. With a more in-depth analysis, the work has the potential of being important and very valuable to both experimental and computational neurobiologists.

    Reviewed by eLife

    This article has 5 evaluationsAppears in 1 listLatest version Latest activity
  8. A causal role of the NMDA receptor in recurrent processing during perceptual integration

    This article has 5 authors:
    1. Samuel Noorman
    2. Timo Stein
    3. Jasper Zantvoord
    4. Johannes Fahrenfort
    5. Simon van Gaal
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      This study presents a new, fundamental finding to the field interested in recurrent processing and its neuromodulatory underpinnings, finding unexpectedly that memantine (blocking NMDA-receptors) enhances the decoding of features thought to rely on NMDA-receptors. This interesting, compelling result identifies new directions for researchers studying consciousness, sensory processing, attention, and neurotransmitters.

    Reviewed by eLife

    This article has 9 evaluationsAppears in 1 listLatest version Latest activity
  9. Analyzing neural response to visual stimuli: Firing rates, frequency band dynamics, and synchrony in near and far flanker conditions

    This article has 3 authors:
    1. Manjeet Kunwar
    2. Nabin Bhusal
    3. Niraj Dhital

    Reviewed by PREreview

    This article has 1 evaluationAppears in 1 listLatest version Latest activity
  10. Homeostatic Synaptic Plasticity of Miniature Excitatory Postsynaptic Currents in Mouse Cortical Cultures Requires Neuronal Rab3A

    This article has 3 authors:
    1. Andrew G Koesters
    2. Mark M Rich
    3. Kathrin L Engisch
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      This valuable study presents findings on the role of the small GTPase Rab3A in homeostatic plasticity. While the study provides solid evidence for a requirement of Rab3A in homeostatic up-scaling in cultured mouse neurons, it does not provide a model of how Rab3A is involved in homeostatic plasticity. The work will be of interest to researchers in the field of synaptic transmission and synaptic plasticity.

    Reviewed by eLife

    This article has 20 evaluationsAppears in 1 listLatest version Latest activity
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