Neuroscience

Efficient coding explains neural response homeostasis and stimulus-specific adaptation

1. Edward James Young
2. Yashar Ahmadian

• Curated by eLife

  eLife Assessment

  This work derives a valuable general theory unifying theories of efficient information transmission in the brain with population homeostasis. The general theory provides an explanation for firing rate homeostasis at the level of neural clusters with firing rate heterogeneity within clusters. Applying this theory to the primary visual cortex, the authors present solid evidence that accounts for stimulus-specific and neuron-specific adaptation. Reviewers have provided additional suggestions for improving the readability of the manuscript, as well as discussing previous results on adapting coding as well as those aspects of experimental data that are not fully explained by the present theory.

Reviewed by eLife

Combinatorial protein barcodes enable self-correcting neuron tracing with nanoscale molecular context

1. Sung Yun Park
2. Arlo Sheridan
3. Bobae An
4. Erin Jarvis
5. Julia Lyudchik
6. William Patton
7. Jun Y. Axup
8. Stephanie W. Chan
9. Hugo G.J. Damstra
10. Daniel Leible
11. Kylie S. Leung
12. Clarence A. Magno
13. Aashir Meeran
14. Julia M. Michalska
15. Franz Rieger
16. Claire Wang
17. Michelle Wu
18. George M. Church
19. Jan Funke
20. Todd Huffman
21. Kathleen G.C. Leeper
22. Sven Truckenbrodt
23. Johan Winnubst
24. Joergen M.R. Kornfeld
25. Edward S. Boyden
26. Samuel G. Rodriques
27. Andrew C. Payne

Reviewed by Arcadia Science