Molecular Biology

  1. 1 H, 13 C and 15 N resonance assignment of the SARS-CoV-2 full-length nsp1 protein and its mutants reveals its unique secondary structure features in solution

    1. Tatiana Agback
    2. Francisco Dominguez
    3. Ilya Frolov
    4. Elena I. Frolova
    5. Peter Agback

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  2. The molecular basis of coupling between poly(A)-tail length and translational efficiency

    1. Kehui Xiang
    2. David P Bartel

    • Curated by eLife

      Evaluation Summary:

      This manuscript addresses a long-standing question, namely how does the poly(A) tail influence translational efficiency? It will therefore be of broad interest to readers from many areas of molecular biology including those interested in translation, mRNA stability, development and gene expression in general. The authors convincingly set out three criteria that must be met for coupling of poly(A) tail length with translation.

      (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #1 agreed to share their name with the authors.)

    Reviewed by eLife

    4 evaluationsAppears in 1 listLatest version Latest activity

  3. Natural variants in SARS-CoV-2 S protein pinpoint structural and functional hotspots: implications for prophylaxis and therapeutic strategies

    1. Suman Pokhrel
    2. Benjamin R. Kraemer
    3. Scott Burkholz
    4. Daria Mochly-Rosen

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  4. An insight into neurotoxic and toxicity of spike fragments SARS-CoV-2 by exposure environment: A threat to aquatic health?

    1. Ives Charlie-Silva
    2. Amanda P. C. Araújo
    3. Abraão T. B. Guimarães
    4. Flávio P Veras
    5. Helyson L. B. Braz
    6. Letícia G. de Pontes
    7. Roberta J. B. Jorge
    8. Marco A. A. Belo
    9. Bianca H V. Fernandes
    10. Rafael H. Nóbrega
    11. Giovane Galdino
    12. Antônio Condino-Neto
    13. Jorge Galindo-Villegas
    14. Glaucia M. Machado-Santelli
    15. Paulo R. S. Sanches
    16. Rafael M. Rezende
    17. Eduardo M. Cilli
    18. Guilherme Malafaia

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  5. Rapid High Throughput Whole Genome Sequencing of SARS-CoV-2 by using One-step RT-PCR Amplification with Integrated Microfluidic System and Next-Gen Sequencing

    1. Tao Li
    2. Hye Kyung Chung
    3. Papa K. Pireku
    4. Brett F. Beitzel
    5. Mark A. Sanborn
    6. Cynthia Y. Tang
    7. Richard Hammer
    8. Detlef Ritter
    9. XiuFeng Wan
    10. Irina Maljkovic Berry
    11. Jun Hang

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  6. The rocaglate CR-31-B (-) inhibits SARS-CoV-2 replication at non-cytotoxic, low nanomolar concentrations in vitro and ex vivo

    1. Christin Müller
    2. Wiebke Obermann
    3. Nadja Karl
    4. Hans-Guido Wendel
    5. Gaspar Taroncher-Oldenburg
    6. Stephan Pleschka
    7. Roland K. Hartmann
    8. Arnold Grünweller
    9. John Ziebuhr

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  7. The aging whole blood transcriptome reveals a potential role of FASLG in COVID-19

    1. Luiz Gustavo de Almeida Chuffa
    2. Jeferson dos Santos Souza
    3. Mariana Costa de Mello
    4. Mario de Oliveira Neto
    5. Robson Francisco Carvalho

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  8. Multivalency transforms SARS-CoV-2 antibodies into broad and ultrapotent neutralizers

    1. Edurne Rujas
    2. Iga Kucharska
    3. Yong Zi Tan
    4. Samir Benlekbir
    5. Hong Cui
    6. Tiantian Zhao
    7. Gregory A. Wasney
    8. Patrick Budylowski
    9. Furkan Guvenc
    10. Jocelyn C. Newton
    11. Taylor Sicard
    12. Anthony Semesi
    13. Krithika Muthuraman
    14. Amy Nouanesengsy
    15. Katherine Prieto
    16. Stephanie A. Bueler
    17. Sawsan Youssef
    18. Sindy Liao-Chan
    19. Jacob Glanville
    20. Natasha Christie-Holmes
    21. Samira Mubareka
    22. Scott D. Gray-Owen
    23. John L. Rubinstein
    24. Bebhinn Treanor
    25. Jean-Philippe Julien

    Reviewed by Rapid Reviews Infectious Diseases, ScreenIT

    3 evaluationsAppears in 2 listsLatest version Latest activity

  9. Evolution of the SARS-CoV-2 proteome in three dimensions (3D) during the first six months of the COVID-19 pandemic

    1. Joseph H. Lubin
    2. Christine Zardecki
    3. Elliott M. Dolan
    4. Changpeng Lu
    5. Zhuofan Shen
    6. Shuchismita Dutta
    7. John D. Westbrook
    8. Brian P. Hudson
    9. David S. Goodsell
    10. Jonathan K. Williams
    11. Maria Voigt
    12. Vidur Sarma
    13. Lingjun Xie
    14. Thejasvi Venkatachalam
    15. Steven Arnold
    16. Luz Helena Alfaro Alvarado
    17. Kevin Catalfano
    18. Aaliyah Khan
    19. Erika McCarthy
    20. Sophia Staggers
    21. Brea Tinsley
    22. Alan Trudeau
    23. Jitendra Singh
    24. Lindsey Whitmore
    25. Helen Zheng
    26. Matthew Benedek
    27. Jenna Currier
    28. Mark Dresel
    29. Ashish Duvvuru
    30. Britney Dyszel
    31. Emily Fingar
    32. Elizabeth M. Hennen
    33. Michael Kirsch
    34. Ali A. Khan
    35. Charlotte Labrie-Cleary
    36. Stephanie Laporte
    37. Evan Lenkeit
    38. Kailey Martin
    39. Marilyn Orellana
    40. Melanie Ortiz-Alvarez de la Campa
    41. Isaac Paredes
    42. Baleigh Wheeler
    43. Allison Rupert
    44. Andrew Sam
    45. Katherine See
    46. Santiago Soto Zapata
    47. Paul A. Craig
    48. Bonnie L. Hall
    49. Jennifer Jiang
    50. Julia R. Koeppe
    51. Stephen A. Mills
    52. Michael J. Pikaart
    53. Rebecca Roberts
    54. Yana Bromberg
    55. J. Steen Hoyer
    56. Siobain Duffy
    57. Jay Tischfield
    58. Francesc X. Ruiz
    59. Eddy Arnold
    60. Jean Baum
    61. Jesse Sandberg
    62. Grace Brannigan
    63. Sagar D. Khare
    64. Stephen K. Burley

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  10. Impact of South African 501.V2 Variant on SARS-CoV-2 Spike Infectivity and Neutralization: A Structure-based Computational Assessment

    1. Mary Hongying Cheng
    2. James M Krieger
    3. Burak Kaynak
    4. Moshe Arditi
    5. Ivet Bahar

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity
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