Microbiology

Vascular dysregulation following SARS-CoV-2 infection involves integrin signalling through a VE-Cadherin mediated pathway

1. Danielle Nader
2. Steve Kerrigan

Reviewed by ScreenIT

The SARS-CoV-2 Delta variant induces an antibody response largely focused on class 1 and 2 antibody epitopes

1. Allison J. Greaney
2. Rachel T. Eguia
3. Tyler N. Starr
4. Khadija Khan
5. Nicholas Franko
6. Jennifer K. Logue
7. Sandra M. Lord
8. Cate Speake
9. Helen Y. Chu
10. Alex Sigal
11. Jesse D. Bloom

Reviewed by ScreenIT

Immunization with recombinant accessory protein-deficient SARS-CoV-2 protects against lethal challenge and viral transmission

1. Chengjin Ye
2. Jun-Gyu Park
3. Kevin Chiem
4. Piyush Dravid
5. Anna Allué-Guardia
6. Andreu Garcia-Vilanova
7. Amit Kapoor
8. Mark R. Walter
9. James J. Kobie
10. Richard K. Plemper
11. Jordi B. Torrelles
12. Luis Martinez-Sobrido

Reviewed by ScreenIT

A broad and potent neutralization epitope in SARS-related coronaviruses

1. Meng Yuan
2. Xueyong Zhu
3. Wan-ting He
4. Panpan Zhou
5. Chengzi I. Kaku
6. Tazio Capozzola
7. Connie Y. Zhu
8. Xinye Yu
9. Hejun Liu
10. Wenli Yu
11. Yuanzi Hua
12. Henry Tien
13. Linghang Peng
14. Ge Song
15. Christopher A. Cottrell
16. William R. Schief
17. David Nemazee
18. Laura M. Walker
19. Raiees Andrabi
20. Dennis R. Burton
21. Ian A. Wilson

Reviewed by ScreenIT

Tracking SARS-CoV-2 Omicron diverse spike gene mutations identifies multiple inter-variant recombination events

1. Junxian Ou
2. Wendong Lan
3. Xiaowei Wu
4. Tie Zhao
5. Biyan Duan
6. Peipei Yang
7. Yi Ren
8. Lulu Quan
9. Wei Zhao
10. Donald Seto
11. James Chodosh
12. Zhen Luo
13. Jianguo Wu
14. Qiwei Zhang

Reviewed by ScreenIT

Development of a ferritin-based nanoparticle vaccine against the SARS-CoV-2 Omicron variant

1. Wanbo Tai
2. Benjie Chai
3. Shengyong Feng
4. Xinyu Zhuang
5. Jun Ma
6. Mujia Pang
7. Lin Pan
8. Zi Yang
9. Mingyao Tian
10. Gong Cheng

Reviewed by ScreenIT

Reconstitution of surface lipoprotein translocation through the Slam translocon

1. Minh Sang Huynh
2. Yogesh Hooda
3. Yuzi Raina Li
4. Maciej Jagielnicki
5. Christine Chieh-Lin Lai
6. Trevor F Moraes

• Curated by eLife

  Evaluation Summary:

  This work provides new insights into how surface-exposed lipoproteins of Gram-negative bacteria reach their destination in the outer membrane. Authors find that the outer membrane protein complex Slam serves as a translocon for the lipoproteins and the periplasmic chaperone Skp mediates their targeting to Slam. This work may contribute to the elucidation of host invasion mechanisms by pathogenic bacteria, in which surface lipoproteins play an important role.

  (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. The reviewers remained anonymous to the authors.)

Reviewed by eLife

Thiopurines inhibit coronavirus Spike protein processing and incorporation into progeny virions

1. Eric S. Pringle
2. Brett A. Duguay
3. Maxwell P. Bui-Marinos
4. Rory P. Mulloy
5. Shelby L. Landreth
6. Krishna Swaroop Desireddy
7. Stacia M. Dolliver
8. Shan Ying
9. Taylor Caddell
10. Trinity H. Tooley
11. Patrick D. Slaine
12. Stephen L. Bearne
13. Darryl Falzarano
14. Jennifer A. Corcoran
15. Denys A. Khaperskyy
16. Craig McCormick

Reviewed by ScreenIT

Dissecting the role of the human microbiome in COVID-19 via metagenome-assembled genomes

1. Shanlin Ke
2. Scott T. Weiss
3. Yang-Yu Liu

Reviewed by ScreenIT

Reorganization of F-actin nanostructures is required for the late phases of SARS-CoV-2 replication in pulmonary cells

1. Jitendriya Swain
2. Peggy Merida
3. Karla Rubio
4. David Bracquemond
5. Israel Aguilar-Ordoñez
6. Stefan Günther
7. Guillermo Barreto
8. Delphine Muriaux

Reviewed by Review Commons, ScreenIT