1. Secreted dengue virus NS1 from infection is predominantly dimeric and in complex with high-density lipoprotein

    This article has 16 authors:
    1. Bing Liang Alvin Chew
    2. AN Qi Ngoh
    3. Wint Wint Phoo
    4. Kitti Wing Ki Chan
    5. Zheng Ser
    6. Nikhil K Tulsian
    7. Shiao See Lim
    8. Mei Jie Grace Weng
    9. Satoru Watanabe
    10. Milly M Choy
    11. Jenny Low
    12. Eng Eong Ooi
    13. Christiane Ruedl
    14. Radoslaw M Sobota
    15. Subhash G Vasudevan
    16. Dahai Luo
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      This potentially useful study aims to advance our understanding of the structure of the native form of a viral toxin secreted from infected cells. While some of the findings confirm previous reports, the new claims in this study are unfortunately only inadequately supported by the methods and analyses used. More rigorous approaches are needed to justify the main conclusion that the structure of the viral toxin derived from infected cells in this study is distinct from previously reported structures of recombinantly expressed versions of the toxin.

    Reviewed by eLife

    This article has 7 evaluationsAppears in 1 listLatest version Latest activity
  2. Quantification of sporozoite expelling by Anopheles mosquitoes infected with laboratory and naturally circulating P. falciparum gametocytes

    This article has 17 authors:
    1. Chiara Andolina
    2. Wouter Graumans
    3. Moussa Guelbeogo
    4. Geert-Jan van Gemert
    5. Jordache Ramijth
    6. Soré Harouna
    7. Zongo Soumanaba
    8. Rianne Stoter
    9. Marga Vegte-Bolmer
    10. Martina Pangos
    11. Photini Sinnis
    12. Katharine Collins
    13. Sarah G Staedke
    14. Alfred B Tiono
    15. Chris Drakeley
    16. Kjerstin Lanke
    17. Teun Bousema
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      This important study combines experimental infections with laboratory and field Plasmodium falciparum isolates to quantify the force of human malaria parasite transmission. By using compelling methodological approaches, the authors establish clear positive correlations between mosquito infection levels (as determined by oocyst numbers), sporozoite loads in salivary glands, and sporozoites expelled during feeding. The link between heterogenous infection levels in the mosquitoes and malaria transmission would be of interest to vector biologists, parasitologists, immunologists, and mathematical modellers.

    Reviewed by eLife

    This article has 10 evaluationsAppears in 1 listLatest version Latest activity
  3. Detecting, mapping, and suppressing the spread of a decade-long Pseudomonas aeruginosa nosocomial outbreak with genomics

    This article has 24 authors:
    1. William Stribling
    2. Lindsey R. Hall
    3. Aubrey Powell
    4. Casey Harless
    5. Melissa J. Martin
    6. Brendan W. Corey
    7. Erik Snesrud
    8. Ana Ong
    9. Rosslyn Maybank
    10. Jason Stam
    11. Katie Bartlett
    12. Brendan T. Jones
    13. Lan N. Preston
    14. Katherine F. Lane
    15. Bernadette Thompson
    16. Lynn M. Young
    17. Yoon I. Kwak
    18. Alice E. Barsoumian
    19. Ana-Elizabeth Markelz
    20. John L. Kiley
    21. Robert J. Cybulski
    22. Jason W. Bennett
    23. Patrick T. Mc Gann
    24. Francois Lebreton
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      This important work presents an example of how genomic data can be used to improve understanding of an ongoing, long-term bacterial outbreak in a hospital with an application to multi-drug resistant Pseudomonas aeruginosa, and will be of interest to researchers concerned with the spread of drug-resistant bacteria in hospital settings. The convincing genomic analyses highlight the value of routine surveillance of patients and environmental sampling and show how such data can help in dating the origin of the outbreak and in characterising the epidemic lineages. These findings highlight the importance of understanding environmental factors contributing to the transmission of P. aeruginosa for guiding and tailoring infection control efforts; however, epidemiological information was limited and the sampling methodology was inconsistent, complicating interpretation of inferences about exact transmission routes.

    Reviewed by eLife

    This article has 4 evaluationsAppears in 1 listLatest version Latest activity
  4. A treasure trove of 1,034 actinomycete genomes

    This article has 13 authors:
    1. Tue Sparholt Jørgensen
    2. Omkar Mohite
    3. Eva B Sterndorff
    4. Maria Alvarez-Arevalo
    5. Kai Blin
    6. Thomas J Booth
    7. Pep Charusanti
    8. David Faurdal
    9. Troels Ø Hansen
    10. Matin Nuhamunada
    11. Anna-Sophie Mourched
    12. Bernhard Ø Palsson
    13. Tilmann Weber

    Reviewed by Arcadia Science

    This article has 13 evaluationsAppears in 1 listLatest version Latest activity
  5. Growing a Cystic Fibrosis-Relevant Polymicrobial Biofilm to Probe Community Phenotypes

    This article has 2 authors:
    1. Sarah Poirier
    2. Fabrice Jean-Pierre

    Reviewed by Arcadia Science

    This article has 1 evaluationAppears in 1 listLatest version Latest activity
  6. Pinpointing the microbiota of tardigrades: What is really there?

    This article has 6 authors:
    1. Bartłomiej Surmacz
    2. Daniel Stec
    3. Monika Prus‐Frankowska
    4. Mateusz Buczek
    5. Łukasz Michalczyk
    6. Piotr Łukasik

    Reviewed by Arcadia Science

    This article has 3 evaluationsAppears in 2 listsLatest version Latest activity
  7. The Toxoplasma monocarboxylate transporters are involved in the metabolism within the apicoplast and are linked to parasite survival

    This article has 13 authors:
    1. Hui Dong
    2. Jiong Yang
    3. Kai He
    4. Wen-Bin Zheng
    5. De-Hua Lai
    6. Jing Liu
    7. Hui-Yong Ding
    8. Rui-Bin Wu
    9. Kevin M Brown
    10. Geoff Hide
    11. Zhao-Rong Lun
    12. Xing-Quan Zhu
    13. Shaojun Long
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      This study identifies two new transporters in the apicoplast, a non-photosynthetic organelle of apicomplexan parasites. While this is important work, it only partially reveals how essential these transporters are, as it does not address the metabolic function of the transporters for the parasite. Although the evidence is still incomplete, the results should be of interest to parasitologists and eukaryotic cell biologists.

    Reviewed by eLife

    This article has 7 evaluationsAppears in 1 listLatest version Latest activity
  8. Cryptic proteins translated from deletion-containing viral genomes dramatically expand the influenza virus proteome

    This article has 15 authors:
    1. Jordan N Ranum
    2. Mitchell P Ledwith
    3. Fadi G Alnaji
    4. Meghan Diefenbacher
    5. Richard Orton
    6. Elizabeth Sloan
    7. Melissa Güereca
    8. Elizabeth M Feltman
    9. Katherine Smollett
    10. Ana da Silva Filipe
    11. Michaela Conley
    12. Alistair B Russell
    13. Christopher B Brooke
    14. Edward Hutchinson
    15. Andrew Mehle

    Reviewed by PREreview

    This article has 1 evaluationAppears in 1 listLatest version Latest activity
  9. Human pluripotent stem cell-derived hepatocyte-like cells for hepatitis D virus studies

    This article has 12 authors:
    1. Huanting Chi
    2. Bingqian Qu
    3. Angga Prawira
    4. Lars Maurer
    5. Jungen Hu
    6. Rebecca M. Fu
    7. Florian A. Lempp
    8. Zhenfeng Zhang
    9. Dirk Grimm
    10. Xianfang Wu
    11. Stephan Urban
    12. Viet Loan Dao Thi

    Reviewed by Review Commons

    This article has 4 evaluationsAppears in 1 listLatest version Latest activity
  10. An assessment of Nano-RECall: Interpretation of Oxford Nanopore sequence data for HIV-1 drug resistance testing

    This article has 8 authors:
    1. Kayla Eileen Delaney
    2. Trevor Ngobeni
    3. Conan K. Woods
    4. Carli Gordijn
    5. Mathilda Claassen
    6. Urvi Parikh
    7. P. Richard Harrigan
    8. Gert Uves van Zyl

    Reviewed by PREreview

    This article has 1 evaluationAppears in 2 listsLatest version Latest activity
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