Microbiology

  1. Identifying and targeting the Mg-Fe-PmrAB regulatory circuit reverses phosphate starvation-driven polymyxin resistance in Enterobacteriaceae

    1. Guangming Zhang
    2. Ziqing Deng
    3. Jiezhang Jiang
    4. Minji Wang
    5. Xiaoyuan Wang
    6. Xiaoyun Liu
    7. Aixin Yan

    • Curated by eLife

      eLife Assessment

      This study characterizes a potentially targetable mechanism by which phosphate scarcity drives polymyxin B resistance in Enterobacteriaceae. The findings are important. While some aspects of the approach are very strong, particularly the diversity of techniques, it is recommended to include genetic controls and antibiotic resistance experiments in order to strengthen the evidence, which is currently solid. The clarity and presentation of the findings could also be improved.

    Reviewed by eLife

    4 evaluationsAppears in 1 listLatest version Latest activity

  4. Simple Sequence Repeats Mediate Phase Variation of the Mucoid Phenotype in Hypervirulent Klebsiella pneumoniae

    1. Oliwia Stawarska
    2. Aarabhi Ravikrishnan Nair
    3. Ania W. Y. Man
    4. Luke R. Green
    5. Ozcan Gazioglu
    6. Francesco Flandi
    7. Margaret M. C. Lam
    8. Kathryn E. Holt
    9. Hasan Yesilkaya
    10. Marco R. Oggioni
    11. Jose A. Bengoechea
    12. Charlotte Odendall
    13. Alex J. McCarthy
    14. Joseph J. Wanford

    Reviewed by PREreview

    1 evaluationAppears in 1 listLatest version Latest activity

  7. A synthetic peptide mimic kills Candida albicans and synergistically prevents infection

    1. Sebastian Schaefer
    2. Raghav Vij
    3. Jakob L. Sprague
    4. Sophie Austermeier
    5. Hue Dinh
    6. Peter R. Judzewitsch
    7. Sven Müller-Loennies
    8. Taynara Lopes Silva
    9. Eric Seemann
    10. Britta Qualmann
    11. Christian Hertweck
    12. Kirstin Scherlach
    13. Thomas Gutsmann
    14. Amy K. Cain
    15. Nathaniel Corrigan
    16. Mark S. Gresnigt
    17. Cyrille Boyer
    18. Megan D. Lenardon
    19. Sascha Brunke

    Reviewed by Rapid Reviews Infectious Diseases

    6 evaluationsAppears in 1 listLatest version Latest activity

  8. A fast-acting inhibitor of blood-stage P. falciparum with mechanism distinct from artemisinin and chloroquine

    1. Stephanie Kabeche
    2. Thomas Meister
    3. Ellen Yeh

    Reviewed by Rapid Reviews Infectious Diseases

    5 evaluationsAppears in 1 listLatest version Latest activity

  9. Functional genomics screens reveal a role for TBC1D24 and SV2B in antibody-dependent enhancement of dengue virus infection

    1. Laura Belmont
    2. Maya Contreras
    3. Catiana H. Cartwright-Acar
    4. Caleb D. Marceau
    5. Aditi Agrawal
    6. Lisa M. Levoir
    7. Jay Lubow
    8. Leslie Goo

    Reviewed by Rapid Reviews Infectious Diseases

    9 evaluationsAppears in 1 listLatest version Latest activity

  10. Release of P-TEFb from the Super Elongation Complex promotes HIV-1 latency reversal

    1. William J. Cisneros
    2. Shimaa H. A. Soliman
    3. Miriam Walter
    4. Lacy M. Simons
    5. Daphne Cornish
    6. Simone De Fabritiis
    7. Ariel W. Halle
    8. Eun-Young Kim
    9. Steven M. Wolinsky
    10. Ramon Lorenzo-Redondo
    11. Ali Shilatifard
    12. Judd F. Hultquist

    Reviewed by Rapid Reviews Infectious Diseases

    6 evaluationsAppears in 1 listLatest version Latest activity
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