Microbiology

  1. Contribution of single mutations to selected SARS-CoV-2 emerging variants spike antigenicity

    1. Shang Yu Gong
    2. Debashree Chatterjee
    3. Jonathan Richard
    4. Jérémie Prévost
    5. Alexandra Tauzin
    6. Romain Gasser
    7. Yuxia Bo
    8. Dani Vézina
    9. Guillaume Goyette
    10. Gabrielle Gendron-Lepage
    11. Halima Medjahed
    12. Michel Roger
    13. Marceline Côté
    14. Andrés Finzi

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  2. Within-host evolutionary dynamics of seasonal and pandemic human influenza A viruses in young children

    1. Alvin X Han
    2. Zandra C Felix Garza
    3. Matthijs RA Welkers
    4. René M Vigeveno
    5. Nhu Duong Tran
    6. Thi Quynh Mai Le
    7. Thai Pham Quang
    8. Dinh Thoang Dang
    9. Thi Ngoc Anh Tran
    10. Manh Tuan Ha
    11. Thanh Hung Nguyen
    12. Quoc Thinh Le
    13. Thanh Hai Le
    14. Thi Bich Ngoc Hoang
    15. Kulkanya Chokephaibulkit
    16. Pilaipan Puthavathana
    17. Van Vinh Chau Nguyen
    18. My Ngoc Nghiem
    19. Van Kinh Nguyen
    20. Tuyet Trinh Dao
    21. Tinh Hien Tran
    22. Heiman FL Wertheim
    23. Peter W Horby
    24. Annette Fox
    25. H Rogier van Doorn
    26. Dirk Eggink
    27. Menno D de Jong
    28. Colin A Russell

    • Curated by eLife

      Evaluation Summary:

      This work offers an in-depth exploration of within-host influenza evolution that helps untangle the process by which global trends arise from host-level dynamics. The manuscript will be of interest to virologists and evolutionary biologists alike, and the dataset provides a unique opportunity to explore evolutionary dynamics late in acute infections of both endemic and emerging viruses. Technical concerns relating to data interpretation and modeling assumptions suggest that some results might change after further investigation.

      (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. The reviewers remained anonymous to the authors.)

    Reviewed by eLife

    5 evaluationsAppears in 1 listLatest version Latest activity

  3. SARS-CoV-2 B.1.351 (beta) variant shows enhanced infectivity in K18-hACE2 transgenic mice and expanded tropism to wildtype mice compared to B.1 variant

    1. Ferran Tarrés-Freixas
    2. Benjamin Trinité
    3. Anna Pons-Grífols
    4. Miguel Romero-Durana
    5. Eva Riveira-Muñoz
    6. Carlos Ávila-Nieto
    7. Mónica Pérez
    8. Edurne Garcia-Vidal
    9. Daniel Pérez-Zsolt
    10. Jordana Muñoz-Basagoiti
    11. Dàlia Raïch-Regué
    12. Nuria Izquierdo-Useros
    13. Ignacio Blanco
    14. Marc Noguera-Julián
    15. Victor Guallar
    16. Rosalba Lepore
    17. Alfonso Valencia
    18. Júlia Vergara-Alert
    19. Bonaventura Clotet
    20. Ester Ballana
    21. Jorge Carrillo
    22. Joaquim Segalés
    23. Julià Blanco

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  4. Structural basis and mode of action for two broadly neutralizing antibodies against SARS-CoV-2 emerging variants of concern

    1. Wenwei Li
    2. Yaozong Chen
    3. Jérémie Prévost
    4. Irfan Ullah
    5. Maolin Lu
    6. Shang Yu Gong
    7. Alexandra Tauzin
    8. Romain Gasser
    9. Dani Vézina
    10. Sai Priya Anand
    11. Guillaume Goyette
    12. Debashree Chaterjee
    13. Shilei Ding
    14. William D. Tolbert
    15. Michael W. Grunst
    16. Yuxia Bo
    17. Shijian Zhang
    18. Jonathan Richard
    19. Fei Zhou
    20. Rick K. Huang
    21. Lothar Esser
    22. Allison Zeher
    23. Marceline Côté
    24. Priti Kumar
    25. Joseph Sodroski
    26. Di Xia
    27. Pradeep D. Uchil
    28. Marzena Pazgier
    29. Andrés Finzi
    30. Walther Mothes

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  5. PGFinder, a novel analysis pipeline for the consistent, reproducible, and high-resolution structural analysis of bacterial peptidoglycans

    1. Ankur V Patel
    2. Robert D Turner
    3. Aline Rifflet
    4. Adelina E Acosta-Martin
    5. Andrew Nichols
    6. Milena M Awad
    7. Dena Lyras
    8. Ivo Gomperts Boneca
    9. Marshall Bern
    10. Mark O Collins
    11. Stéphane Mesnage

    • Curated by eLife

      Evaluation Summary:

      This manuscript presents the development and validation of a new tool for the characterization of peptidoglycan (PG), the essential cell wall polymer of bacteria. PG is a single large macromolecule that protects almost all bacterial cells. The newly developed open access tool will greatly facilitate comparative quantitative analyses and the determination of compositional diversity of PG, which might ultimately contribute to the development of new antibacterials that target this essential cell wall component.

      (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #2 and Reviewer #3 agreed to share their names with the authors.)

    Reviewed by eLife

    4 evaluationsAppears in 1 listLatest version Latest activity

  6. The SARS-CoV-2 Lambda variant exhibits enhanced infectivity and immune resistance

    1. Izumi Kimura
    2. Yusuke Kosugi
    3. Jiaqi Wu
    4. Jiri Zahradnik
    5. Daichi Yamasoba
    6. Erika P. Butlertanaka
    7. Yuri L. Tanaka
    8. Keiya Uriu
    9. Yafei Liu
    10. Nanami Morizako
    11. Kotaro Shirakawa
    12. Yasuhiro Kazuma
    13. Ryosuke Nomura
    14. Yoshihito Horisawa
    15. Kenzo Tokunaga
    16. Takamasa Ueno
    17. Akifumi Takaori-Kondo
    18. Gideon Schreiber
    19. Hisashi Arase
    20. Chihiro Motozono
    21. Akatsuki Saito
    22. So Nakagawa
    23. Kei Sato

    Reviewed by Rapid Reviews Infectious Diseases, ScreenIT

    3 evaluationsAppears in 2 listsLatest version Latest activity

  7. A method for the generation of pseudotyped virus particles bearing SARS coronavirus spike protein in high yields

    1. Yoichiro Fujioka
    2. Sayaka Kashiwagi
    3. Aiko Yoshida
    4. Aya O. Satoh
    5. Mari Fujioka
    6. Maho Amano
    7. Yohei Yamauchi
    8. Yusuke Ohba

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  8. SARS-CoV-2 in the Republic of Guinea: Fragment and Whole-Genome Sequencing, Phylogenetic Analysis

    1. A.A. Kritsky
    2. Ya.M. Krasnov
    3. M. Keita
    4. S. Keita
    5. A.V. Fedorov
    6. A.P. Shevtsova
    7. N.P. Guseva
    8. E.V. Kazorina
    9. E.A. Sosedova
    10. A.D. Katyshev
    11. E.A. Naryshkina
    12. E.V. Kolomoets
    13. S.A. Shcherbakova
    14. A.Yu. Popova
    15. V.V. Kutyrev

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  9. Increased aerosol transmission for B.1.1.7 (alpha variant) over lineage A variant of SARS-CoV-2

    1. Julia R. Port
    2. Claude Kwe Yinda
    3. Victoria A. Avanzato
    4. Jonathan E. Schulz
    5. Myndi G. Holbrook
    6. Neeltje van Doremalen
    7. Carl Shaia
    8. Robert J. Fischer
    9. Vincent J. Munster

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  10. Highly Efficient SARS-CoV-2 Infection of Human Cardiomyocytes: Spike Protein-Mediated Cell Fusion and Its Inhibition

    1. Chanakha K. Navaratnarajah
    2. David R. Pease
    3. Peter J. Halfmann
    4. Biruhalem Taye
    5. Alison Barkhymer
    6. Kyle G. Howell
    7. Jon E. Charlesworth
    8. Trace A. Christensen
    9. Yoshihiro Kawaoka
    10. Roberto Cattaneo
    11. Jay W. Schneider

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity
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