Microbiology

  1. SARS-CoV-2 neutralising antibodies in Dogs and Cats in the United Kingdom

    1. Shirley L. Smith
    2. Enyia. R. Anderson
    3. Cintia Cansado-Utrilla
    4. Tessa Prince
    5. Sean Farrell
    6. Bethaney Brant
    7. Stephen Smyth
    8. Peter-John M. Noble
    9. Gina L. Pinchbeck
    10. Nikki Marshall
    11. Larry Roberts
    12. Grant L. Hughes
    13. Alan D. Radford
    14. Edward I. Patterson

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  2. Effect of Prophylactic Use of Intranasal Oil Formulations in the Hamster Model of COVID-19

    1. Zaigham Abbas Rizvi
    2. Manas Ranjan Tripathy
    3. Nishant Sharma
    4. Sandeep Goswami
    5. N Srikanth
    6. J. L. N. Sastry
    7. Shailendra Mani
    8. Milan Surjit
    9. Amit Awasthi
    10. Madhu Dikshit

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  3. No evidence of SARS-CoV-2 infection in Neotropical Primates sampled during COVID-19 pandemic in Minas Gerais and Rio Grande do Sul, Brazil

    1. Filipe Vieira Santos de Abreu
    2. Mariana Viana Macedo
    3. Alex Junio Jardim da Silva
    4. Cirilo Henrique de Oliveira
    5. Vinícius de Oliveira Ottone
    6. Marco Antônio Barreto de Almeida
    7. Edmilson dos Santos
    8. Jader da Cruz Cardoso
    9. Aline Scarpellini Campos
    10. Claudia Maria Dornelles da Silva
    11. Amanda Gonzales da Silva
    12. Miguel de Souza Andrade
    13. Valéria Magro Octaviano Bernis
    14. Walter Octaviano Bernis Filho
    15. Giliane de Souza Trindade
    16. George Rego Albuquerque
    17. Anaiá da Paixão Sevá
    18. Bergmann Morais Ribeiro
    19. Danilo Simonini Teixeira
    20. Fabrício Souza Campos
    21. Ana Cláudia Franco
    22. Paulo Michel Roehe
    23. Danilo Bretas de Oliveira

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  4. Pyrimidine biosynthesis inhibitors synergize with nucleoside analogs to block SARS-CoV-2 infection

    1. David C. Schultz
    2. Robert M. Johnson
    3. Kasirajan Ayyanathan
    4. Jesse Miller
    5. Kanupriya Whig
    6. Brinda Kamalia
    7. Mark Dittmar
    8. Stuart Weston
    9. Holly L. Hammond
    10. Carly Dillen
    11. Lauren Castellana
    12. Jae Seung Lee
    13. Minghua Li
    14. Emily Lee
    15. Samuel Constant
    16. Marc Ferrer
    17. Christoph A. Thaiss
    18. Matthew B. Frieman
    19. Sara Cherry

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  5. A Bifluorescent-Based Assay for the Identification of Neutralizing Antibodies against SARS-CoV-2 Variants of Concern In Vitro and In Vivo

    1. Kevin Chiem
    2. Desarey Morales Vasquez
    3. Jesus A. Silvas
    4. Jun-Gyu Park
    5. Michael S. Piepenbrink
    6. Julien Sourimant
    7. Michelle J. Lin
    8. Alexander L. Greninger
    9. Richard K. Plemper
    10. Jordi B. Torrelles
    11. Mark R. Walter
    12. Juan C. de la Torre
    13. James K. Kobie
    14. Chengjin Ye
    15. Luis Martinez-Sobrido

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  6. KAHRP dynamically relocalizes to remodeled actin junctions and associates with knob spirals in Plasmodium falciparum ‐infected erythrocytes

    1. Cecilia P. Sanchez
    2. Pintu Patra
    3. Shih‐Ying Scott Chang
    4. Christos Karathanasis
    5. Lukas Hanebutte
    6. Nicole Kilian
    7. Marek Cyrklaff
    8. Mike Heilemann
    9. Ulrich S. Schwarz
    10. Mikhail Kudryashev
    11. Michael Lanzer

    Reviewed by Review Commons

    4 evaluationsAppears in 1 listLatest version Latest activity

  7. Genetic depletion studies inform receptor usage by virulent hantaviruses in human endothelial cells

    1. Maria Eugenia Dieterle
    2. Carles Solà-Riera
    3. Chunyan Ye
    4. Samuel M Goodfellow
    5. Eva Mittler
    6. Ezgi Kasikci
    7. Steven B Bradfute
    8. Jonas Klingström
    9. Rohit K Jangra
    10. Kartik Chandran

    • Curated by eLife

      Evaluation Summary:

      This is a well-performed study that defines the role of purported host cell receptors in the entry of hantaviruses into human endothelial cells. This is an important study as it applies CRISPR-mediated deletion studies for candidate receptors in the same endothelial cell line (TIME).

      (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #2 agreed to share their name with the authors.)

    Reviewed by eLife

    4 evaluationsAppears in 1 listLatest version Latest activity

  8. Enhanced fusogenicity and pathogenicity of SARS-CoV-2 Delta P681R mutation

    1. Akatsuki Saito
    2. Takashi Irie
    3. Rigel Suzuki
    4. Tadashi Maemura
    5. Hesham Nasser
    6. Keiya Uriu
    7. Yusuke Kosugi
    8. Kotaro Shirakawa
    9. Kenji Sadamasu
    10. Izumi Kimura
    11. Jumpei Ito
    12. Jiaqi Wu
    13. Kiyoko Iwatsuki-Horimoto
    14. Mutsumi Ito
    15. Seiya Yamayoshi
    16. Samantha Loeber
    17. Masumi Tsuda
    18. Lei Wang
    19. Seiya Ozono
    20. Erika P. Butlertanaka
    21. Yuri L. Tanaka
    22. Ryo Shimizu
    23. Kenta Shimizu
    24. Kumiko Yoshimatsu
    25. Ryoko Kawabata
    26. Takemasa Sakaguchi
    27. Kenzo Tokunaga
    28. Isao Yoshida
    29. Hiroyuki Asakura
    30. Mami Nagashima
    31. Yasuhiro Kazuma
    32. Ryosuke Nomura
    33. Yoshihito Horisawa
    34. Kazuhisa Yoshimura
    35. Akifumi Takaori-Kondo
    36. Masaki Imai
    37. The Genotype to Phenotype Japan (G2P-Japan) Consortium
    38. Mika Chiba
    39. Hirotake Furihata
    40. Haruyo Hasebe
    41. Kazuko Kitazato
    42. Haruko Kubo
    43. Naoko Misawa
    44. Nanami Morizako
    45. Kohei Noda
    46. Akiko Oide
    47. Mai Suganami
    48. Miyoko Takahashi
    49. Kana Tsushima
    50. Miyabishara Yokoyama
    51. Yue Yuan
    52. Shinya Tanaka
    53. So Nakagawa
    54. Terumasa Ikeda
    55. Takasuke Fukuhara
    56. Yoshihiro Kawaoka
    57. Kei Sato

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  9. Structure of Mycobacterium tuberculosis cytochrome bcc in complex with Q203 and TB47, two anti-TB drug candidates

    1. Shan Zhou
    2. Weiwei Wang
    3. Xiaoting Zhou
    4. Yuying Zhang
    5. Yuezheng Lai
    6. Yanting Tang
    7. Jinxu Xu
    8. Dongmei Li
    9. Jianping Lin
    10. Xiaolin Yang
    11. Ting Ran
    12. Hongming Chen
    13. Luke W Guddat
    14. Quan Wang
    15. Yan Gao
    16. Zihe Rao
    17. Hongri Gong

    • Curated by eLife

      Evaluation Summary:

      The authors have determined the atomic resolution cryo-EM structures of M. tuberculosis cytochrome bcc at 2.7 Å resolution and in complex with anti-tuberculous drugs Q203 at 2.7 Å and TB47 at 2.9 Å resolution. The Q203 compound is a drug candidate otherwise known as Telacebec with promising results in phase 2 clinical trials. The complex structure could pave the way for rational-based drug design.

      (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #1 agreed to share their name with the authors.)

    Reviewed by eLife

    5 evaluationsAppears in 1 listLatest version Latest activity

  10. Western diet increases COVID-19 disease severity in the Syrian hamster

    1. Julia R. Port
    2. Danielle R. Adney
    3. Benjamin Schwarz
    4. Jonathan E. Schulz
    5. Daniel E. Sturdevant
    6. Brian J. Smith
    7. Victoria A. Avanzato
    8. Myndi G. Holbrook
    9. Jyothi N. Purushotham
    10. Kaitlin A. Stromberg
    11. Ian Leighton
    12. Catharine M. Bosio
    13. Carl Shaia
    14. Vincent J. Munster

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity
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